• • • Transcriptomics
  • • Evolution biology

  • • Database
  • • Software tool

  Bgee

  Gene expression expertise
• • • Proteins & Proteomes
  • • Systems Biology

  • • Database
  • • Software tool

  STRING

  Protein-protein interaction networks and enrichment analysis
• • • Proteins & Proteomes
  • • Lipidomics

  • • Database

  SwissLipids

  Knowledge resource for lipids
• • • Systems Biology

  • • Database

  Cellosaurus

  Knowledge resource on cell lines
• • • Genomics
  • • Population genetics

  • • Software tool

  V-pipe

  Viral genomic variant detection pipeline
• • • Genomics
  • • Evolution biology

  • • Software tool

  Nextstrain

  Real-time tracking of pathogen evolution
• • • Metagenomics
  • • Population genetics

  • • Database
  • • Software tool

  mOTUs

  Microbial taxonomic and population genomic profiler
• • • Proteins & Proteomes

  • • Database

  UniProtKB/Swiss-Prot

  Protein knowledgebase
• • • Proteins & Proteomes
  • • Metabolomics

  • • Database

  Rhea

  Expert-curated database of biochemical reactions
• • • Genes & Genomes
  • • Evolution & Phylogeny

  • • Database
  • • Software tool

  SwissOrthology

  One-stop shop for orthologs
• • • Medicinal chemistry

  • • Database
  • • Software tool

  SwissDrugDesign

  Widening access to computer-aided drug design
• • • Transcriptomics
  • • Evolution & Phylogeny
  • • Systems Biology

  • • Database
  • • Software tool

  SwissRegulon Portal

  Tools and data for regulatory genomics
• • • Proteins & Proteomes
  • • Structural Biology

  • • Database
  • • Software tool

  SWISS-MODEL

  Protein structure homology-modelling
• • • Transcriptomics

  • • Database
  • • Software tool

  ASAP

  Web-based, cooperative portal for single-cell data analyses
• • • Genes & Genomes

  • • Database
  • • Software tool

  SPSP | Swiss Pathogen Surveillance Platform

  Public Swiss pathogen NGS data
• • • Proteins & Proteomes
  • • Glycomics

  • • Database
  • • Software tool

  Glyco@Expasy

  Zooming in on web-based glycoinformatics resources
• • • Genes & Genomes
  • • Evolution biology

  • • Software tool

  BEAST2

  Statistical framework for pathogen genome evolution analysis

Other Resources of SIB Groups

• • • Proteins & Proteomes

  • • Database

  UniProtKB

  Protein sequence database
• • • Genomics
  • • Evolution biology

  • • Database

  Selectome

  Database of positive selection
• • • Proteins & Proteomes

  • • Database

  PROSITE

  Protein family and domain database
• • • Proteins & Proteomes
  • • Structural Biology

  • • Database

  SWISS-MODEL Repository

  Protein structure homology models
• • • Proteins & Proteomes
  • • Medicinal chemistry

  • • Software tool

  SwissDock

  Docking of small ligands into protein active sites
• • • Proteins & Proteomes

  • • Database

  ENZYME

  Enzyme nomenclature database
• • • Proteins & Proteomes

  • • Database
  • • Software tool

  HAMAP

  UniProtKB family classification and annotation
• • • Genes & Genomes
  • • Proteins & Proteomes
  • • Structural Biology

  • • Database

  ViralZone

  Knowledgebase on virus biology and viral proteins
• • • Proteins & Proteomes

  • • Database
  • • Software tool

  neXtProt

  Human protein knowledgebase
• • • Evolution & Phylogeny

  • • Database

  OrthoDB

  Ortholog evolutionary and functional annotations
• • • Evolution & Phylogeny

  • • Database
  • • Software tool

  OMA

  Orthology inference among complete genomes
• • • Proteins & Proteomes
  • • Metabolomics

  • • Database
  • • Software tool

  MetaNetX

  Metabolic network repository & analysis
• • • Proteins & Proteomes

  • • Database

  VenomZone

  Portal to venom protein UniProtKB entries
• • • Population genetics

  • • Software tool

  Arlequin

  An integrated software for population genetics data analysis
• • • Proteins & Proteomes
  • • Glycomics

  • • Database

  UniLectin

  Structural and functional classification of lectins
• • • Structural Biology
  • • Glycomics

  • • Database

  UniCarb-DB

  Glycan structures and associated mass spectrometry data
• • • Genomics

  • • Database
  • • Software tool

  EPD

  Eukaryotic Promoter Database
• • • Proteins & Proteomes
  • • Structural analysis

  • • Software tool

  SwissTargetPrediction

  Target prediction for bioactive small molecules
• • • Medicinal chemistry

  • • Software tool

  SwissSimilarity

  Ligand-based virtual screening
• • • Proteins & Proteomes
  • • Structural analysis

  • • Database

  SwissSidechain

  Database of non-natural amino acid side chains
• • • Transcriptomics

  • • Software tool

  TagScan

  Genome-wide sequence tag scanner
• • • Transcriptomics
  • • Systems Biology

  • • Database

  SwissRegulon

  Database of genome-wide annotations of regulatory sites
• • • Structural analysis

  • • Software tool

  SwissParam

  Topology and parameters for small molecules
• • • Proteins & Proteomes
  • • Structural analysis

  • • Database

  SwissBioIsostere

  Database of molecular replacements for ligand design
• • • Medicinal chemistry

  • • Software tool

  SwissADME

  Pharmacokinetics properties and druglikeness
• • • Glycomics

  • • Software tool

  SugarSketcher

  Fast, intuitive, SNFG-compliant glycan structure drawing
• • • Proteins & Proteomes
  • • Glycomics

  • • Database

  SugarBind

  Pathogen Sugar-Binding Database
• • • Genomics

  • • Software tool

  SSA

  Analysis of nucleic acid sequence motifs
• • • Genomics

  • • Database
  • • Software tool

  SNP2TFBS

  Regulatory SNPs affecting TF binding site affinity
• • • Transcriptomics

  • • Software tool

  SIBsim4

  Align expressed RNA sequences on a DNA template
• • • Genomics

  • • Software tool

  ShoRAH

  Analysis of NGS data
• • • Genes & Genomes
  • • Evolution & Phylogeny

  • • Software tool

  REALPHY

  Inference of phylogenetic trees from genome data
• • • Transcriptomics

  • • Software tool

  QuasR

  Quantification and analysis of Short Reads
• • • Proteins & Proteomes
  • • Structural analysis

  • • Software tool

  QMEAN

  Protein model quality estimation
• • • Genes & Genomes
  • • Systems Biology

  • • Database

  Progenetix

  Genomic profiles of cancer samples with focus on CNV
• • • Proteins & Proteomes

  • • Software tool

  pftools

  Build, calibrate, and search biological sequences
• • • Proteins & Proteomes

  • • Database
  • • Software tool

  PaxDb

  Protein abundance across several organisms
• • • Structural analysis

  • • Software tool

  OpenStructure

  Molecular modelling and visualisation environment
• • • Genomics
  • • Systems Biology

  • • Database

  arrayMAP

  Curated array data repository for cancer genomics
• • • Proteins & Proteomes

  • • Software tool

  MSight

  Mass Spectrometry Imager
• • • Transcriptomics

  • • Software tool

  miRmap

  Prediction of microRNA target repression strength
• • • Genomics

  • • Software tool

  MADAP

  Clustering tool of genomic sites
• • • Genomics

  • • Software tool

  IScan

  Insertion sequence identification in whole genomes
• • • Genomics
  • • Systems Biology

  • • Database
  • • Software tool

  iPtgxDBs

  Platform for integrated proteogenomics databases
• • • Proteins & Proteomes

  • • Software tool

  MELANIE

  2-D PAGE analysis
• • • Glycomics

  • • Software tool

  Glynsight

  Visualise and compare glycan expression profiles
• • • Glycomics

  • • Software tool

  Glydin'

  Network representation of known glycan determinants
• • • Proteins & Proteomes
  • • Glycomics

  • • Software tool

  GlycoSiteAlign

  Multiple alignment of sequences around glycosylation sites
• • • Proteins & Proteomes
  • • Glycomics

  • • Database

  GlyConnect

  Integrated data platform to study glycosylation
• • • Genes & Genomes
  • • Evolution biology

  • • Software tool

  GenomeHistory

  Gene duplicate identification
• • • Transcriptomics

  • • Software tool

  FetchGWI / tagger

  Short sequence mapping
• • • Genomics
  • • Population genetics

  • • Software tool

  fastsimcoal

  Fast sequential Markov coalescent simulation of genomic data
• • • Genomics

  • • Software tool

  FastEpistasis

  Tool for quantitative trait epistasis
• • • Transcriptomics
  • • Evolution biology

  • • Software tool

  BUSCO

  From QC to gene prediction and phylogenomics
• • • Transcriptomics
  • • Proteins & Proteomes

  • • Software tool

  Translate

  Convert a nucleotide sequence to a protein sequence
• • • Proteins & Proteomes

  • • Software tool

  Sulfinator

  Predict tyrosine sulfation sites in protein sequences
• • • Proteins & Proteomes

  • • Software tool

  SIM

  Alignment of two protein sequences or within a sequence
• • • Proteins & Proteomes

  • • Software tool

  RandSeq

  Random protein sequence generator
• • • Proteins & Proteomes

  • • Software tool

  ProtScale

  Profile produced by amino acids scales on protein sequences
• • • Proteins & Proteomes

  • • Database

  ABCD

  Database of chemically defined antibodies
• • • Proteins & Proteomes

  • • Software tool

  ProtParam

  Computation of physico chemical parameters of a protein
• • • Proteins & Proteomes

  • • Software tool

  PRATT

  Conserved patterns in a set of protein sequences
• • • Proteins & Proteomes

  • • Software tool

  PeptideMass

  Theoretical protein cleavage by a given enzyme
• • • Proteins & Proteomes

  • • Software tool

  PeptideCutter

  Potential cleavage sites in a protein
• • • Proteins & Proteomes
  • • AI and machine learning

  • • Software tool

  Myristoylator

  N-terminal myristoylation of proteins by neural networks
• • • Proteins & Proteomes

  • • Software tool

  MALDIPepQuant

  Quantify MALDI peptides from Phenyx output
• • • Proteins & Proteomes

  • • Software tool

  HAMAP-Scan

  Scanning of protein sequences against HAMAP families
• • • Proteins & Proteomes
  • • Glycomics

  • • Software tool

  GlycoMod

  Possible oligosaccharide structures on proteins from masses
• • • Proteins & Proteomes

  • • Software tool

  FindPept

  Unspecific protein cleavage from experimental masses
• • • Proteins & Proteomes

  • • Software tool

  FindMod

  Potential PTMs and single amino acid substitutions
• • • Proteins & Proteomes

  • • Software tool

  Decrease redundancy

  Redundancy reduction in a set of sequences
• • • Proteins & Proteomes

  • • Software tool

  Compute pI/MW

  Isoelectric point and molecular weight from protein sequence
• • • Proteins & Proteomes

  • • Software tool

  UniProt ClustalO

  Align two or more protein sequences
• • • Proteins & Proteomes

  • • Software tool

  UniProt BLAST

  BLAST sequence similarity search on the UniProt web site
• • • Genomics

  • • Database
  • • Software tool

  ChIP-Seq

  ChIP-Seq data analysis tools
• • • Proteins & Proteomes
  • • Structural analysis

  • • Database

  Click2Drug

  Directory of computational drug design tools
• • • Transcriptomics
  • • Systems Biology

  • • Software tool

  CRUNCH

  Automated pipeline for ChIP-seq data analysis
• • • Proteins & Proteomes

  • • Software tool

  Dotlet

  Regions of close similarity in 2 sequences
• • • Systems Biology

  • • Software tool

  CLASTR

  Cellosaurus STR similarity search tool
• • • Proteins & Proteomes
  • • Structural analysis

  • • Software tool

  SWISS-MODEL Workspace

  Fully automated protein structure homology-modeling server
• • • Proteins & Proteomes
  • • Systems Biology

  • • Database

  TCS

  Predict interaction specificity in bacterial signalling
• • • Genomics
  • • Evolution biology

  • • Software tool

  CT-CBN

  Estimate conjunctive Bayesian networks
• • • Transcriptomics
  • • Systems Biology

  • • Software tool

  ISA

  Finding modules in gene expression data
• • • Transcriptomics
  • • Systems Biology

  • • Software tool

  ExpressionView

  Biclusters identified in gene expression data
• • • Transcriptomics
  • • Systems Biology

  • • Software tool

  ISMARA

  Webservice for gene expression and epigenetic data analysis
• • • Genomics
  • • Systems Biology

  • • Software tool

  Phylogibbs

  Regulatory sites in a collection of DNA sequences
• • • Proteins & Proteomes

  • • Software tool

  ScanProsite

  Protein sequences against PROSITE
• • • Genomics
  • • Population genetics

  • • Software tool

  V-pipe SARS-CoV-2

  V-pipe pipeline for SARS-CoV-2 sequencing data
• • • Genomics

  • • Database

  TASmania

  Toxin-antitoxin database
• • • Genomics

  • • Software tool

  TASer

  Search tool associated to TASmania
• • • Evolution & Phylogeny

  • • Database

  OMA SPARQL endpoint

  SPARQL access to the OMA Orthology database
• • • Transcriptomics
  • • Evolution biology

  • • Database

  Bgee SPARQL endpoint

  SPARQL access to the Bgee gene expression database
• • • Evolution & Phylogeny

  • • Database

  OrthoDB SPARQL endpoint

  SPARQL access to the OrthoDB catalog of orthologs
• • • Metagenomics

  • • Software tool

  LEMMI

  Continuous benchmarking of methods for metagenomics
• • • Proteins & Proteomes

  • • Database

  HAMAP SPARQL endpoint

  SPARQL access to the HAMAP annotation rules
• • • Proteins & Proteomes

  • • Database

  UniProt SPARQL endpoint

  SPARQL access to UniProt and related data
• • • Evolution & Phylogeny

  • • Software tool

  OrthoLoger

  Accurate and scalable inference of groups of orthologs
• • • Proteins & Proteomes

  • • Software tool

  rawrr

  R package for fast reading Thermo Fisher Scientific MS data
• • • Transcriptomics

  • • Database

  PolyAsite

  Database of curated RNA polyadenylation sites
• • • Proteins & Proteomes
  • • Metabolomics

  • • Database

  Rhea SPARQL endpoint

  SPARQL access to the Rhea knowledgebase
• • • AI and machine learning

  • • Database
  • • Software tool

  SIBiLS

  Personalized information retrieval from the literature
• • • Proteins & Proteomes
  • • Glycomics

  • • Database

  GAG-DB

  3D structures of glycosaminoglycans
• • • Evolution & Phylogeny

  • • Software tool

  raxmlGUI

  raxmlGUI 2.0 is a graphical user interface to RAxML
• • • Glycomics

  • • Software tool

  GlyConnect Compozitor

  Contextualises glycan composition sets
• • • Glycomics

  • • Software tool

  HMO-Glycologue

  Simulator of Human Milk Oligosaccharide synthesis
• • • AI and machine learning

  • • Software tool

  Variomes

  Search engine to support the curation of genomic variants
• • • Metagenomics

  • • Software tool

  mVIRs

  Prediction tool for inducible, bacteria-infecting viruses
• • • Systems Biology

  • • Software tool

  OMAMO

  OMAMO allows the user to find the best simple model organism
• • • Evolution & Phylogeny

  • • Software tool

  Phylo.io

  A tool for visualising and comparing phylogenetic trees
• • • Evolution & Phylogeny

  • • Database

  SwissTree

  A collection of gold standard gene phylogenies
• • • Genomics
  • • Evolution & Phylogeny

  • • Software tool

  Nextclade

  Clade assignment and quality control for viral genomes
• • • Proteins & Proteomes
  • • Lipidomics

  • • Database

  SwissLipids SPARQL endpoint

  SPARQL access to the SwissLipids knowledgebase
• • • Proteins & Proteomes
  • • Metabolomics

  • • Database

  MetaNetX SPARQL endpoint

  SPARQL access to MetaNetX
• • • Systems Biology

  • • Database

  SwissBioPics

  Subcellular location visualization
• • • Proteins & Proteomes
  • • AI and machine learning

  • • Database

  MHC Motif Atlas

  MHC Motif Atlas
• • • Structural Biology

  • • Database

  ModelArchive

  Repository of predicted macromolecular structure models
• • • Proteins & Proteomes
  • • Structural Biology

  • • Database
  • • Software tool

  CAMEO

  Weekly automated benchmarking of protein structure modelling
• • • Evolution biology
  • • Systems Biology
  • • AI and machine learning

  • • Software tool

  CAPTAIN

  Decision-support tool for conservation area prioritization
• • • Transcriptomics

  • • Database

  Glittr

  Git repositories with bioinformatics training material
• • • Genes & Genomes
  • • Systems Biology

  • • Database

  cancercelllines.org

  Genomic variants in human cancer cell lines
• • • Genes & Genomes
  • • Systems Biology

  • • Software tool

  CREMA

  Cis-Regulatory Element Motif Activities
• • • Transcriptomics
  • • Systems Biology

  • • Software tool

  DWT-online

  Dinucleotide Weight Tensor toolbox and visualisation service
• • • Systems Biology

  • • Database

  Cellosaurus SPARQL endpoint

  SPARQL access to Cellosaurus
• • • Genomics
  • • Evolution biology

  • • Software tool

  GenSpectrum

  Real-time pathogen genomic sequence analysis
• • • Proteins & Proteomes
  • • Systems Biology

  • • Database

  Protein Universe Atlas

  Interactive, annotated similarity network of all proteins
• • • Proteins & Proteomes

  • • Software tool

  OMArk

  OMArk determines the quality and completeness of gene sets
• • • AI and machine learning

  • • Database

  SIBiLS SPARQL endpoint

  SPARQL access to SIBiLS, the SIB Literature Services
• • • AI and machine learning

  • • Software tool

  BiotXplorer

  Biotic interactions from scientific publications
• • • AI and machine learning

  • • Software tool

  Biodiversity PMC

  Search a large collection of scientific publications
• • • Proteins & Proteomes
  • • AI and machine learning

  • • Database

  EnzChemRED

  Enzyme Chemistry Relation Extraction Dataset
• • • Glycomics

  • • Software tool

  GlycoQL

  Match a glycan substructure to a database of full structures
• • • Genomics

  • • Database

  Pathoplexus

  Human viral pathogen genomic data sharing platform
• • • Transcriptomics
  • • Systems Biology

  • • Software tool

  Cellstates

  Infering clusters of cells in scRNA-seq data
• • • Transcriptomics
  • • Systems Biology

  • • Software tool

  Sanity

  Single-cell RNA-Seq normalization method
• • • Proteins & Proteomes
  • • Glycomics

  • • Database

  MatrixDB

  Extracellular proteins and polysaccharides interactions
• • • Proteins & Proteomes

  • • Software tool

  prolfqua

  R package for protein differential expression analysis
• • • Metagenomics

  • • Database
  • • Software tool

  Microbe Atlas

  Explore the microbiome of the world
• • • Proteins & Proteomes
  • • Evolution & Phylogeny

  • • Software tool

  OMAmer

  Alignment-free protein subfamily assignment
• • • Transcriptomics
  • • Systems Biology

  • • Software tool

  Bonsai

  Analysis of single cell RNA-seq data
• • • Structural Biology
  • • Systems Biology

  • • Software tool

  SimuCell3D

  Tissue simulation in 3D
• • • Structural Biology
  • • Systems Biology

  • • Software tool

  PolyHoop

  Cell and tissue dynamics simulation in 2D
• • • Proteins & Proteomes
  • • AI and machine learning

  • • Database
  • • Software tool

  MixTCRpred

  Predictor of TCR-epitope interactions
• • • Evolution biology
  • • Systems Biology

  • • Database

  MoultDB

  Integrative resource on moulting in arthropods
• • • Metagenomics

  • • Software tool

  MAGFlow/BIgMAG

  Metagenome metrics and taxonomical annotation visualization
• • • Transcriptomics

  • • Database
  • • Software tool

  Fly Cell Atlas

  Single-cell transcriptomes of the entire adult Drosophila
• • • Transcriptomics

  • • Database
  • • Software tool

  Human Cell Atlas

  Mapping the human body at the cellular level
• • • Proteins & Proteomes

  • • Software tool

  MyDomains

  Protein domains image creator
• • • Metagenomics

  • • Database

  BeeBiome

  Bee-associated microbes/viruses
• • • Genomics

  • • Software tool

  Loculus

  Infrastructure for managing pathogen genomic data
• • • Transcriptomics
  • • Proteins & Proteomes
  • • Systems Biology

  • • Software tool

  NOODAI

  Multi-omics data analysis and integration
• • • Genes & Genomes
  • • Proteins & Proteomes

  • • Software tool

  MetaGraph

  Petabase-scale sequence search
• • • Proteins & Proteomes
  • • Evolution & Phylogeny

  • • Database
  • • Software tool

  Orthology Benchmarking

  Quest for Orthologs benchmarking service
• • • Systems Biology

  • • Database

  SPHN Metadata Catalog

  Central access point for FAIR health datasets in Switzerland
• • • Systems Biology

  • • Database

  SPHN SPARQL endpoint

  SPARQL access to the SPHN data
• • • Metagenomics
  • • Systems Biology

  • • Database

  HuMSub Catalog

  Human gut microbiota subspecies catalog
• • • Evolution & Phylogeny
  • • Structural Biology

  • • Software tool

  Foldtree

  Phylogenetic tree from predicted protein structures
• • • Evolution & Phylogeny

  • • Software tool

  FastOMA

  Orthology inference at scale
• • • Drug design

  • • Software tool

  BindCraft

  Design of functional protein binders
• • • Genomics
  • • Evolution & Phylogeny

  • • Software tool

  RECOPHY

  Recombination pattern analysis based on phylogeny
• • • Proteins & Proteomes
  • • Evolution & Phylogeny

  • • Software tool

  TEA

  The Embedded Alphabet for proteins
• • • Population genetics

  • • Software tool

  STUN

  Simulation on TUnable fitNess landscapes