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  • CAZy  •  CAZy is a dedicated family classification system correlating structure and molecular mechanism of carbohydrate-active enzymes. It describes the families of structurally-related catalytic and carbohydrate-binding modules (or functional domains) of enzymes that degrade, modify, or create glycosidic bonds.  [less]
  • CSDB  •  CSDB covers information on structures and taxonomy of natural carbohydrates published in the literature and mostly resolved by nuclear magnetic resonance (NMR). CSDB is composed of two parts: Bacterial & Archeal (BCSDB) and Plant & Fungal (PFCSDB). The databases can be queried together or separately with multiple criteria. Supporting tools for NMR data analysis and prediction as well as statistical analysis of glycomes in taxa are included  [less]
  • Glyco3D  •  A single entry portal to access three-dimensional features of (1) carbohydrate and carbohydrate polymers in different physical and biological conditions, a nd (2) carbohydrate-binding proteins crystallised with their carbohydrate ligands (lectins, monoclonal antibodies, glycosyltransferases). Most data is structural data arising from diffraction experiments, but three-dimensional models resulting from theoretical calculations are also included. 3D structures can be viewed across the website. [less]
  • GlyConnect  •  GlyConnect is a platform integrating several sources of information to characterise the molecular actors of glycosylation, mainly glycoproteins and N- and O-linked glycans. The purpose of GlyConnect is to bring out in a single resource the relationships between glycans, the proteins that carries them, the enzymes that synthesise or degrade them and the proteins that bind them. GlyConnect also integrates tools otherwise accessible individually in the glycomics collection of ExPASy.  [less]
  • Glycopedia  •  GlycoPedia collects e-chapters on basic, intermediary and advanced topics of glycoscience. It also compiles various sources and suggests relevant readings to the scientific community. [less]
  • GlycoStore  •  GlycoStore is a curated chromatographic, electrophoretic and mass-spectrometry composition database of N-, O-, glycosphingolipid (GSL) glycans and free oligosaccharides associated with a range of glycoproteins, glycolipids and biotherapeutics. The database is built on publicly available experimental data sets from GlycoBase (NIBRT, Ireland), Bioprocessing Technology Institute (BTI) A*STAR, Macquarie University and Ludger Ltd. [less]
  • GlyTouCan  •  GlyTouCan is the international glycan structure repository. It is an uncurated registry for glycan structures that assigns globally unique accession numbers to any glycan independent of the level of information provided by the experimental method used to identify the structure(s). [less]
  • MatrixDB  •  MatrixDB is a curated database of interactions between extracellular matrix proteins, proteoglycans and polysaccharides. It mainly focuses on protein-glycosaminoglycan (GAG) interactions, as GAGs are complex and abundant polysaccharides in the ECM and at the cell surface, where they play key roles in adhesion and signaling.  [less]
  • SugarBind  •  SugarBind covers knowledge of glycan binding of human pathogen lectins and adhesins. Information is collected by experts from articles published in peer-reviewed scientific journals. The data were compiled through an exhaustive search of literature published over the past 30 years by glycobiologists, microbiologists, and medical histologists.  [less]
  • UniCarb-DB  •  UniCarb-DB stores data and information on glycan structures and associated fragment data characterised by LC-MS/MS strategies. It is annotated with high-quality datasets. [less]
  • UniCarbKB  •  UniCarbKB is a curated and annotated glycan database which curates information from the scientific literature on glycoprotein derived glycan structures. It includes data previously available from GlycoSuiteDB. [less]
  • UniLectin  •  UniLectin is a platform integrating information regarding non-enzymatic carbohydrate-binding proteins usually referred to as lectins with the prospect of building and refining a structural and functional classification of these proteins. It includes the reference Lectin3D a database of 3D structures curated from the PDB.  [less]


  • DrawGlycan  •  DrawGlycan-SNFG uses IUPAC-condensed string inputs to generate glycan and glycopeptide drawings. Bond fragmentation in either glycans or glycopeptides as well as other glycan descriptors can be included.  [less]
  • EpitopeXtractor  •  Glycan structures submitted to EpitopeXtractor are compared to the complete collection of glycan determinants stored in the Glydin' network ( The tool extracts all matching substructures and displays them as SNFG cartoons (Symbol Nomenclature for Glycans (SNFG) described here with the option of mapping the results on the Glydin' network.  [less]
  • GLYCAM-Web  •  The tools at GLYCAM-Web automate the prediction of 3D structures of glycans, glycosaminoglycans, and glycoproteins, and provide all files necessary for the user to perform molecular dynamics simulations of these systems with the AMBER software package. Additional tools facilitate the prediction of the specificity of glycan binding proteins, such as lectins and antibodies, and provide theoretical 3D structures for these complexes.  [less]
  • GlycanAnalyzer  •  Exoglycosidase cleavage of monosaccharides results in signature peak shifts, in both UPLC and MS1. Manual interpretation of exoglycosidase data is complex and time consuming. GlycanAnalyzer is a web application that pattern matches N-glycan peak shifts following exoglycosidase digestion and automates structure assignments. GlycanAnalyzer significantly improves assignment accuracy over other auto-assignment methods on tests with a monoclonal antibody.  [less]
  • GlycanMass  •  Calculate the mass of an oligosaccharide structure. [less]
  • GlycoDigest  •  GlycoDigest is a tool that simulates the action of these exoglycosidases on released oligosaccharides. It assists glycobiologists in designing enzyme mixtures that can be used to guide the precise determination of glycan structures. [less]
  • GlycoDomain Viewer  •  The GlycoDomain Viewer is a tool for the visualisation of glycosylation sites in the context of the protein and conserved domains. It contains O-glycoproteomic data from the Clausen lab, and predictions of GalNAc-type glycosylation for the human proteome. [less]
  • GlycoMod  •  Predict possible oligosaccharide structures that occur on proteins from their experimentally determined masses. The program can be used for free or derivatized oligosaccharides and for glycopeptides. [less]
  • GlyConnect  •  GlyConnect is a platform integrating several sources of information to characterise the molecular actors of glycosylation, mainly glycoproteins and N- and O-linked glycans. The purpose of GlyConnect is to bring out in a single resource the relationships between glycans, the proteins that carries them, the enzymes that synthesise or degrade them and the proteins that bind them. GlyConnect also integrates tools otherwise accessible individually in the glycomics collection of ExPASy.  [less]
  • GlycoSiteAlign  •  GlycoSiteAlign selectively aligns amino acid sequences surrounding glycosylation sites (by default, 20 positions on each side of the glycosylated residue) depending on structural properties of the glycan attached to the site. These properties are either general (e.g., "fucosylated") or specific, such as precise composition, and are proposed in a drop-down list.  [less]
  • Glydin'  •  Glydin' compiles and maps information relative to glycoepitopes (glycan determinants) as published in the literature or reported in databases. The output is an interactive network of structurally related glycan sub-structures. [less]
  • Glynsight  •  Glynsight is a web interface to upload, visualize and interactively compare glycan expression profiles. The tool can process N- or O-linked glycan expression data. [less]
  • GlyS3  •  GlyS3 matches any substructure such as glycan determinants to a large collection of structures recorded in Glyconnect or SugarBind. [less]
  • MzJava  •  MzJava is an open-source Java library for the analysis of mass spectrometry data. It provides algorithms and data structures for processing mass spectra and their associated biological molecules, such as small molecules, glycans, proteins, and peptides with post-translational modifications. MzJava includes methods to perform mass calculation, protein digestion, peptide and glycan fragmentation, MS/MS signal processing, and scoring for spectra-spectra and peptide/glycan-spectra matches.  [less]
  • NetCGlyc  •  Neural network predictions of C-mannosylation sites in mammalian proteins.  [less]
  • NetNGlyc  •  NetNGlyc predicts N-Glycosylation sites in human proteins using artificial neural networks that examine the sequence context of Asn-Xaa-Ser/Thr sequons.  [less]
  • NetOGlyc  •  Neural network predictions of mucin type GalNAc O-glycosylation sites in mammalian proteins. [less]
  • O-Glycologue  •  Built from a model of the de novo biosynthesis of O-linked glycans, O-Glycologue is a method for generating networks of reactions based on the activities of a set of 26 human glycosyltransferase and sulfotransferase enzymes. The effects of enzyme knock-outs on the network can be predicted, and also the enzymes required to produce a given O-glycan.  [less]
  • PepSweetener  •  PepSweetener supports the manual annotation of MS data for intact glycopeptides. It displays an interactive map of all theoretical glycopeptides that match the molecular masses of queried precursor ions. Ion matching can be performed in two modes: simple when the search space spans the combination of all tryptic peptides including N-glycosites in the human proteome, and advanced when the search space is custom-built by specifying peptides and glycans. [less]
  • SugarSketcher  •  SugarSketcher was designed to provide users with a simple and efficient interface for drawing glycan molecules with the logos defined in the Symbol Nomenclature for Glycans (SNFG) . The tool operates in a quick mode in which the top menu shows a limited set of logos or in a normal mode in which the top menu is comprehensive. In either cases, a structure can be drawn from scratch or from a core structure. Structures are exportable as .svg images or in the GlycoCT format.  [less]
  • Swiss Mass Abacus  •  Swiss Mass Abacus is a calculator of peptide and glycopeptide masses. It is purposefully kept as simple as a basic calculator executing arithmetic operations. [less]
  • YinOYang  •  The YinOYang WWW server produces neural network predictions for O-beta-GlcNAc attachment sites in eukaryotic protein sequences. This server can also use NetPhos, to mark possible phosphorylated sites and hence identify "Yin-Yang" sites.  [less]
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