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ExPASy: SIB Bioinformatics Resource Portal - Resources
Categories: genomics, (sequence alignment, similarity search), systems biology - Software type(s): CLI, GUI, website - tool
Phylogibbs is an algorithm for discovering regulatory sites in a collection of DNA sequences, including multiple alignments of orthologous sequences from related organisms.The algorithm uses a Gibbs sampling strategy, takes the phylogenetic relationships of the input sequences rigorously into account, and assigns realistic posterior probabilities to reported sites using a novel annealing+tracking strategy.