New in Expasy: TEA (and STEAM)

Posted 17 June 2026
New in Expasy: TEA (and STEAM)

Interested in carrying out highly sensitive and efficient large-scale protein homology searches? STEAM, Search with TEA against Many, performs a fast search against large datasets of proteins translated to TEA (The Embedded Alphabet).

The preprint Rewriting protein alphabets with language models introduces a novel approach using contrastive learning to convert protein language model embeddings into a new 20-letter alphabet, TEA, enabling highly efficient large-scale protein homology searches.

Share this article

Latest News

New Cellosaurus release

Posted 30 June 2026
New Cellosaurus release

The diversity and coverage of Cellosaurus has been expanded through the integration of new patient-derived and commercially available cell line collections in version 56. Check out this latest release!

New in Expasy: FastOMA

Posted 01 June 2026
New in Expasy: FastOMA

Do you need to infer orthology relationships? Try FastOMA - it can be used on 2000 eukaryotic proteomes in a day. FastOMA maintains the high accuracy and resolution of the well-established Orthologous Matrix (OMA) approach in benchmarks.