New in Expasy: BindCraft

Posted 11 June 2026

BindCraft is an automated pipeline for de novo protein binder design. Interested in running this pipeline? You'll find everything you need on GitHub.

BindCraft has successfully been used to design binders against a diverse set of challenging targets, including cell-surface receptors, common allergens, de novo designed proteins and multi-domain nucleases, such as CRISPR–Cas9. Read about it in this Nature paper.

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