BindCraft is an automated pipeline for de novo protein binder design. Interested in running this pipeline? You'll find everything you need on GitHub.
BindCraft has successfully been used to design binders against a diverse set of challenging targets, including cell-surface receptors, common allergens, de novo designed proteins and multi-domain nucleases, such as CRISPR–Cas9. Read about it in this Nature paper.
Interested in the population genetics of complex polygenic traits during adaptation? STUN is a flexible and user-friendly software package for simulating the polygenic adaptation of recombining haploid populations using either new mutations or standing genetic variation.
A new version of the OMA Browser is out! This 32nd release covers 2,983 genomes. For the specifics of the new and updated genomes, refer to this OMA Blog entry.
Glittr.org lists Git repositories with educational materials for the computational life sciences. The latest update improves its interoperability. [Read more]
You may encounter problems accessing Expasy on Tuesday July 14th from 18 h to 20h (CEST) due to maintenance work.
The diversity and coverage of Cellosaurus has been expanded through the integration of new patient-derived and commercially available cell line collections in version 56. Check out this latest release!