Species code:	TREPA
Taxonomy:	Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Treponema (TaxID: 160) [NEWT/ NCBI]
Description:	Treponema pallidum (Spirochete), is a helical to sinusoidal bacterium with 2 membranes, a thin peptidoglycan layer and flagella that lie in the periplasmic space. It is the causative agent of syphilis. Even if the primary infection is localized, bacteria rapidly disseminate and cause manifestations in the cardiovascular and nervous systems. It is an obligate human parasite.
Properties:	Presence of flagella: Yes Interaction: Animal pathogen in Mammalia Number of membranes: 2 Number of inteins:0
Statistics:	Number of TREPA entries in the UniProt Knowledgebase: 1028 (614 in UniProtKB/Swiss-Prot + 414 in UniProtKB/TrEMBL)

Genome structure:	Chromosome EMBL accession number AE000520 (circular; 1,138,011 bp) (download entry) (download Genome Reviews).
Reference(s):	[1] MEDLINE=98332770; PubMed=9665876; [ NCBI , EBI , Israel , Japan ] Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G., Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A., Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D., Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R., McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A., Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O., Venter J.C. ; "Complete genome sequence of Treponema pallidum, the syphilis spirochete."; Science 281:375-388(1998).
Web links:	CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Treponema&GLspecies=pallidum&GLstrain=Nichols Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid243276%5Borgn%5D GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Tpal_NICHOLS Karyn's Genomes: http://www.ebi.ac.uk/2can/genomes/bacteria/Treponema_pallidum.html NMPDR: http://www.nmpdr.org/FIG/seedviewer.cgi?pattern=243276.1;page=SearchResult PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p5_Tre_palli TIGR CMR: http://cmr.tigr.org/tigr-scripts/CMR/GenomePage.cgi?database=gtp  EBI Proteome Analysis page

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