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Showing 11 records out of 11 total

Categories: proteomics, (function analysis), systems biology - Software type(s): website - tool
Digitized version of the Roche Applied Science "Biochemical Pathways" wall chart. The map, linked to relevant ENZYME database entries, can be browsed online, and keyword searches are available.
Categories: proteomics, (function analysis) - Software type(s): website - database
ENZYME is a repository of information relative to the nomenclature of enzymes. It is primarily based on the recommendations of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB) and it describes each type of characterized enzyme for which an EC (Enzyme Commission) number has been provided.
Categories: proteomics, glycomics - Software type(s): website - tool
GlycoDigest is a tool that simulates the action of these exoglycosidases on released oligosaccharides. It assists glycobiologists in designing enzyme mixtures that can be used to guide the precise determination of glycan structures.
Categories: proteomics, (function analysis), systems biology - Software type(s): website, databases files - database/tool
MetaNetX.org allows to access, analyse and manipulate genome-scale metabolic networks as well as biochemical pathways. It consistently integrates data from various public resources and makes the data accessible in a standardized format using a common namespace. Models can be interactively compared, analysed (e.g. detection of dead-end metabolites/reactions, flux balance analysis or simulation of reaction/gene knockouts), manipulated and exported. Users can upload their own metabolic models.
Categories: proteomics, (function analysis) - Software type(s): website - tool
PeptideCutter predicts potential substrate cleavage sites, cleaved by proteases or chemicals in a given protein sequence. The tool returns the query sequence with the possible cleavage sites mapped on it and/or a table of cleavage site positions.
Categories: proteomics, (function analysis) - Software type(s): website - tool
The PoPS project is a set of computational tools for investigating protease specificity. The main PoPS program allows users to model and profile protease specificity and predict substrate cleavage. Other tools are available to search for substrates within proteomes (protein databases for organisms), and create simple matrix models of specificity from experimental data.
Categories: proteomics, (function analysis), systems biology - Software type(s): website - database
Rhea is a comprehensive and non-redundant resource of expert curated biochemical reactions described using species from ChEBI (Chemical Entities of Biological Interest). Rhea has been designed for the functional annotation of enzymes and the description, analysis and reconciliation of genome-scale metabolic networks. Rhea reactions are extensively curated with links to source literature and are mapped to other resources such as SwissLipids, MetaNetX, Reactome, BioCyc, KEGG and UniPathway.
Categories: proteomics, (function analysis), systems biology - Software type(s): website - database
SwissLipids is a comprehensive reference database that links mass spectrometry-based lipid identifications to curated knowledge of lipid structures, metabolic reactions, enzymes and interacting proteins. It features approximately 500,000 lipid structures from more than 115 lipid classes and over 3,000 enzymatic reactions and 800 proteins.
Categories: proteomics, (function analysis) - Software type(s): website - database
UniPathway is a curated resource of metabolic pathways for the UniProtKB/Swiss-Prot knowledgebase.
Categories: proteomics, (protein sequences and identification, function analysis, similarity search/alignment) - Software type(s): website - database
The UniProt Knowledgebase (UniProtKB) is produced by the UniProt consortium and is the central hub for the collection of functional information on proteins with accurate, consistent and rich annotation. It consists of: UniProtKB/Swiss-Prot (manually-annotated records and curator-evaluated computational analysis) and UniProtKB/TrEMBL (computationally analyzed records awaiting manual annotation).
Categories: proteomics, (protein sequences and identification, function analysis, protein modifications, protein interactions) - Software type(s): website - database
UniProtKB/Swiss-Prot is the manually annotated component of UniProtKB (produced by the UniProt consortium). It contains manually-annotated (reviewed) records with information extracted from the literature and curator-evaluated computational analysis.