ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MQVDPVVYQL QRAVSQDPIA VKDAEGHLNN WKKEPGFFGK LYSIFLDKQN DMSLRWIAII 

        70         80         90        100        110        120 
QLRNSIDIIW RKNTKMSLLP EERDFIRCNA LLGSIKSENL LSIQNALVVS RIARLDYPTE 

       130        140        150        160        170        180 
WPSLFHDLLG KLQQSLGTGD YDVALRLLIT LHHIIKAMAG NRLLRSRQIF YKLAPELLTI 

       190        200        210        220        230        240 
LQPILHSSLS SWMMILESSK EIKDSTLLSY MQISRYTLKA CRRLVVFGFQ NPSESEFSER 

       250        260        270        280        290        300 
MLAFCAVHQR KLLSMLGTML QSSRSPIVVG ECLEMAFAHA FLFNKPFFDF SFYSPCLTKF 

       310        320        330        340        350        360 
PATIDYISLH YDFLGQISSH LSSYKEKFEE SSKNFEKLVI MSLRVFILVI QEFCNTKSSH 

       370        380        390        400        410        420 
PETAQVLYNS FLVDNRINNL LDLLITKLLI LKEEDFEEWT DSPQQWVLEQ STQDVEFNVR 

       430        440        450        460        470        480 
PCAEKLLKCF FDAYGDIIVS PFKDMIYSVF ECPKTLTQAV QQDTLISSFG VGYTQLKSIF 

       490        500        510        520        530        540 
PFAKWLQEAA VPNMASINDI GISRVYRRRI AIFLSQWIED SSSEQLLEVI YKLYCSFLNL 

       550        560        570        580        590        600 
TDPCNDAVVI LTTIDAFKTV LDDWNFSENS FLSIKENLFV HVLSLFKAFE SVDARTSILS 

       610        620        630        640        650        660 
LLGTLLARAG EHVAPMESTI ASLLSQLWDG WKKEPLLRAR VLAVMHQFVN AIKAKSFEFS 

       670        680        690        700        710        720 
TFLYTVIEYC VNPESPEHVI FEADAMELWS TFLMYIQKLP ETFTLLIPHL LYHLSQATST 

       730        740        750        760        770        780 
LPFVLMIVSS YQLLDNTVLM KDYSFTIFEK LNDLLDDVKN ETLQALCKTV CLLIETTPMD 

       790        800        810        820        830        840 
MIYESLLNSS LLSRLLLSIA TNDKHPQVLI EYLLVVSRIS LREPELILKV CQTKNINIAM 

       850        860        870        880        890        900 
LIGNWILLND HINHSKDRKL NTLALSSLLR TNHPDVLAVL DSIMNLWFSV LSEVEEDANG 

       910        920        930        940        950        960 
DATIYYKNDD YSAVGFYLDE TSEEMTRRKQ LLLKDPVHSV NSRSFFISVF MFCRDANGGM 

       970        980 
ENFQNQYLST VNPALLEQFQ SML 

References and documentation are available.

Number of amino acids: 983

Molecular weight: 112934.87

Theoretical pI: 5.48

Amino acid composition: 
Ala (A)  52	  5.3%
Arg (R)  38	  3.9%
Asn (N)  47	  4.8%
Asp (D)  52	  5.3%
Cys (C)  16	  1.6%
Gln (Q)  42	  4.3%
Glu (E)  60	  6.1%
Gly (G)  24	  2.4%
His (H)  21	  2.1%
Ile (I)  69	  7.0%
Leu (L) 143	 14.5%
Lys (K)  51	  5.2%
Met (M)  28	  2.8%
Phe (F)  59	  6.0%
Pro (P)  34	  3.5%
Ser (S)  95	  9.7%
Thr (T)  47	  4.8%
Trp (W)  15	  1.5%
Tyr (Y)  31	  3.2%
Val (V)  59	  6.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 112
Total number of positively charged residues (Arg + Lys): 89

Atomic composition:

Carbon      C	      5143
Hydrogen    H	      8044
Nitrogen    N	      1294
Oxygen      O	      1470
Sulfur      S	        44

Formula: C5143H8044N1294O1470S44
Total number of atoms: 15995

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   129690
Abs 0.1% (=1 g/l)   1.148, assuming all pairs of Cys residues form cystines


Ext. coefficient   128690
Abs 0.1% (=1 g/l)   1.140, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 47.72
This classifies the protein as unstable.



Aliphatic index: 106.81

Grand average of hydropathicity (GRAVY): 0.088