ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MCFGVLLSGH YYVMVHLLWK LYYIIGRGLG LLTLLMWKEP EIESPTPKTV TSISWYLLEE 

        70         80         90        100        110        120 
LCCLFRFIYS IQNRERKCKN GPSPNKRGSA SGCSRRGGGR GSGYKTLYRD LCENKPTPEL 

       130 
WTLQAPELNL 

References and documentation are available.

Number of amino acids: 130

Molecular weight: 14909.45

Theoretical pI: 9.22

Amino acid composition: 
Ala (A)   2	  1.5%
Arg (R)   9	  6.9%
Asn (N)   5	  3.8%
Asp (D)   1	  0.8%
Cys (C)   6	  4.6%
Gln (Q)   2	  1.5%
Glu (E)   9	  6.9%
Gly (G)  13	 10.0%
His (H)   2	  1.5%
Ile (I)   6	  4.6%
Leu (L)  20	 15.4%
Lys (K)   8	  6.2%
Met (M)   3	  2.3%
Phe (F)   3	  2.3%
Pro (P)   8	  6.2%
Ser (S)  10	  7.7%
Thr (T)   7	  5.4%
Trp (W)   4	  3.1%
Tyr (Y)   8	  6.2%
Val (V)   4	  3.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 10
Total number of positively charged residues (Arg + Lys): 17

Atomic composition:

Carbon      C	       675
Hydrogen    H	      1056
Nitrogen    N	       180
Oxygen      O	       183
Sulfur      S	         9

Formula: C675H1056N180O183S9
Total number of atoms: 2103

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    34295
Abs 0.1% (=1 g/l)   2.300, assuming all pairs of Cys residues form cystines


Ext. coefficient    33920
Abs 0.1% (=1 g/l)   2.275, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 52.07
This classifies the protein as unstable.



Aliphatic index: 88.46

Grand average of hydropathicity (GRAVY): -0.231