ExPASy Proteomics Server

Accession	MF_01958
Dates	22-MAY-2006 (Created) 25-NOV-2009 (Last updated, Version 8)

Data class

Protein

Predictors

HAMAP; MF_01958; [distribution of match scores in UniProtKB];[seed alignment for MF_01958]

Names

Acetyl_esterase

Identifier

AES

Protein name

RecName: Full=Acetyl esterase; EC=3.1.1.-;

Gene name

aes

FUNCTION: Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates malT activity by antagonizing maltotriose binding. Inhibits melA galactosidase activity (By similarity).

SUBUNIT: Homodimer. Interacts with malT and melA (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the 'GDXG' lipolytic enzyme family.

PROSITE	PS01173; LIPASE_GDXG_HIS; 1; PS01174; LIPASE_GDXG_SER; 1;
Pfam	PF07859; Abhydrolase_3; 1;

Cytoplasm, Hydrolase, Serine esterase.

GO:0004091; Molecular function: carboxylesterase activity.
GO:0005737; Cellular component: cytoplasm.

From: AES_ECOLI (P23872)
Key		From		To		Description		Condition		FTGroup
ACT_SITE		165		165		By similarity		S
ACT_SITE		262		262		By similarity		D
ACT_SITE		292		292		By similarity		H

Size range:	272-323 amino acids
Related UniRules:	None
Template:	P23872 (AES_ECOLI)
Scope:	Bacteria; Enterobacteriales
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None