HAMAP rule MF_01853
General rule information
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Accession | MF_01853 |
Dates | 18-DEC-2008 (Created)
1-JUN-2023 (Last updated, Version 10) |
Name | PelO |
Scope(s) |
Archaea |
Template(s) | Q9HJ74 (PELO_THEAC); P96026 (PELO_SACS2); [ Recover all ] |
Triggered by |
HAMAP; MF_01853 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | PELO |
Protein name | RecName: Full=Protein pelota homolog; EC=3.1.-.-; |
Gene name | Name=pelA; |
Comments
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FUNCTION | May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. |
COFACTOR | Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240; |
SUBUNIT | Monomer. |
SUBCELLULAR LOCATION | Cytoplasm. |
DOMAIN | The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity. |
SIMILARITY | Belongs to the eukaryotic release factor 1 family. Pelota subfamily. |
Keywords
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Gene Ontology
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GO:0004519; Molecular function:endonuclease activity |
GO:0046872; Molecular function:metal ion binding |
GO:0005737; Cellular component:cytoplasm |
Cross-references
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Pfam | PF03463; eRF1_1; 1; |
Pfam | PF03464; eRF1_2; 1; |
Pfam | PF03465; eRF1_3; 1; |
NCBIfam | TIGR00111; Pelota; 1; |
Features
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Additional information
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Size range | 328-360 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |