HAMAP rule MF_01674
General rule information
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| Accession | MF_01674 |
| Dates | 7-OCT-2008 (Created)
1-JUN-2023 (Last updated, Version 13) |
| Name | Sep_tRNA_synth |
| Scope(s) |
Archaea |
| Template(s) | Q59054 (SEPS_METJA); O30126 (SEPS_ARCFU); [ Recover all ] |
| Triggered by |
HAMAP; MF_01674 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | SEPS |
| Protein name | RecName: Full=O-phosphoserine--tRNA(Cys) ligase; Short=O-phosphoserine--tRNA ligase; EC=6.1.1.27; AltName: Full=Non-canonical O-phosphoseryl-tRNA(Cys) synthetase; AltName: Full=O-phosphoseryl-tRNA(Cys) synthetase; Short=SepRS; |
| Gene name | Name=sepS; |
Comments
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| FUNCTION | Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys). |
| CATALYTIC ACTIVITY | Reaction=ATP + O-phospho-L-serine + tRNA(Cys) = AMP + diphosphate + O- phospho-L-seryl-tRNA(Cys); Xref=Rhea:RHEA:25678, Rhea:RHEA-COMP:9661, Rhea:RHEA-COMP:9719, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57524, ChEBI:CHEBI:78442, ChEBI:CHEBI:78551, ChEBI:CHEBI:456215; EC=6.1.1.27; |
| SUBUNIT | Homotetramer. Interacts with SepCysS. |
| SIMILARITY | Belongs to the class-II aminoacyl-tRNA synthetase family. O-phosphoseryl-tRNA(Cys) synthetase subfamily. |
Keywords
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Gene Ontology
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| GO:0004812; Molecular function:aminoacyl-tRNA ligase activity |
| GO:0005524; Molecular function:ATP binding |
| GO:0043039; Biological process:tRNA aminoacylation |
Cross-references
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Features
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| From: SEPS_ARCFU (O30126) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 186 | 188 | /ligand="substrate" | H-M-T | ||||||||
| BINDING | 231 | 233 | /ligand="substrate" | S-A-S | ||||||||
| BINDING | 273 | 274 | /ligand="substrate" | Y-Y | ||||||||
| BINDING | 325 | 325 | /ligand="substrate" | N | ||||||||
Additional information
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| Size range | 526-562 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |