HAMAP family: MF

General rule information

Accession	MF_01133
Dates	25-SEP-2003 (Created) 7-JUN-2008 (Last updated, Version 20)

Data class

Protein

Predictors

HAMAP; MF_01133; [distribution of match scores in UniProtKB];[seed alignment for MF_01133]

Propagated annotation

Identifier, protein and gene names

Identifier

RBL

Protein name

RecName:

Full=Ribulose bisphosphate carboxylase;
Short=RuBisCO;
EC=4.1.1.39;

Gene name

rbcL

Comments

CATALYTIC ACTIVITY: 2 3-phospho-D-glycerate + 2 H(+) = D-ribulose 1,5-bisphosphate + CO(2) + H(2)O.

CATALYTIC ACTIVITY: 3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O(2).

case <FTGroup:1>

COFACTOR: Binds 1 magnesium ion per subunit (By similarity).

end case

SUBUNIT: Homodimer (By similarity).

MISCELLANEOUS: The basic functional RuBisCO is composed of a large chain homodimer in a "head-to-tail" conformation. In contrast to form I RuBisCO, the form III RuBisCO are composed solely of large subunits (By similarity).

SIMILARITY: Belongs to the RuBisCO large chain family. Type III subfamily.

Cross-references

Pfam	PF00016; RuBisCO_large; 1; PF02788; RuBisCO_large_N; 1;

Keywords

Carbon dioxide fixation, Lyase, Monooxygenase, Oxidoreductase.

case <FTGroup:1>

Magnesium, Metal-binding.

end case

Gene Ontology

case <FTGroup:1>

GO:0000287; Molecular function: magnesium ion binding.

end case

GO:0016984; Molecular function: ribulose-bisphosphate carboxylase activity.

Features

`From: RBL_PYRKO (O93627)`
`Key`	`From`	`To`	`Description`	`Condition`	`FTGroup`
`ACT_SITE`	`163`	`163`	`Proton acceptor (By similarity)`	`K`
`ACT_SITE`	`281`	`281`	`Proton acceptor (By similarity)`	`H`

`METAL`	`189`	`189`	`Magnesium (via carbamate group) (By similarity)`	`K`	`1`
`METAL`	`191`	`191`	`Magnesium (By similarity)`	`D`	`1`
`METAL`	`192`	`192`	`Magnesium (By similarity)`	`E`	`1`

`BINDING`	`111`	`111`	`Substrate; in homodimeric partner (By similarity)`	`N`
`BINDING`	`165`	`165`	`Substrate (By similarity)`	`K`
`BINDING`	`282`	`282`	`Substrate (By similarity)`	`R`
`BINDING`	`314`	`314`	`Substrate (By similarity)`	`H`
`BINDING`	`367`	`367`	`Substrate (By similarity)`	`S`
`SITE`	`322`	`322`	`Transition state stabilizer (By similarity)`	`K`
`MOD_RES`	`189`	`189`	`N6-carboxylysine (By similarity)`	`K`

Additional information

Size range:	420-444 amino acids
Related UniRules:	MF_01338 (RBL); MF_01339 (RBL2)
Template:	O93627 (RBL_PYRKO); Q58632 (RBL_METJA); O28635 (RBL_ARCFU): [Recover all]
Scope:	Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None

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