HAMAP rule MF_00679
General rule information
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| Accession | MF_00679 |
| Dates | 16-JUL-2003 (Created)
1-JUN-2023 (Last updated, Version 23) |
| Name | HscA |
| Scope(s) |
Bacteria |
| Template(s) | P0A6Z1 (HSCA_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_00679 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | HSCA |
| case <OC:Enterobacterales> | |
| Protein name | RecName: Full=Chaperone protein HscA; AltName: Full=Hsc66; |
| else | |
| Protein name | RecName: Full=Chaperone protein HscA homolog; |
| end case | |
| Gene name | Name=hscA; |
Comments
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| case <OC:Enterobacterales> | |
| FUNCTION | Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. |
| else | |
| FUNCTION | Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. |
| end case | |
| SIMILARITY | Belongs to the heat shock protein 70 family. |
Keywords
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Gene Ontology
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| GO:0016887; Molecular function:ATP hydrolysis activity |
| GO:0006457; Biological process:protein folding |
Cross-references
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| Pfam | PF00012; HSP70; 1; |
| PRINTS | PR00301; HEATSHOCK70; 1; |
| PROSITE | PS00297; HSP70_1; 1; |
| PROSITE | PS00329; HSP70_2; 1; |
| PROSITE | PS01036; HSP70_3; 1; |
| NCBIfam | TIGR01991; HscA; 1; |
Features
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Additional information
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| Size range | 586-622 amino acids |
| Related rules |
MF_00332 |
| Fusion | Nter: None Cter: None |
| Comments | Divergent YERPE and YERPS with insert not shown in alignment or taken in size range |