HAMAP logo

HAMAP rule MF_00284

Send feedback

General rule information [?]

Accession MF_00284
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 31)
Name Phe_tRNA_synth_beta2
Scope(s) Bacteria
Archaea
Template(s) O26864 (SYFB_METTH); A5K464 (SYFB_PLAVS); [ Recover all ]
Triggered by HAMAP; MF_00284 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier SYFB
Protein name RecName: Full=Phenylalanine--tRNA ligase beta subunit;
                 EC=6.1.1.20;
AltName: Full=Phenylalanyl-tRNA synthetase beta subunit;
                 Short=PheRS;
Gene name Name=pheT;

Comments [?]

CATALYTIC ACTIVITY Reaction=ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe); Xref=Rhea:RHEA:19413, Rhea:RHEA-COMP:9668, Rhea:RHEA-COMP:9699, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:58095, ChEBI:CHEBI:78442, ChEBI:CHEBI:78531, ChEBI:CHEBI:456215; EC=6.1.1.20;
COFACTOR Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
SUBUNITTetramer of two alpha and two beta subunits.
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

Keywords [?]


Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0004826; Molecular function:phenylalanine-tRNA ligase activity
GO:0006432; Biological process:phenylalanyl-tRNA aminoacylation
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF03483; B3_4; 1;
Pfam PF03484; B5; 1;
NCBIfam TIGR00471; PheT_arch; 1;
PROSITE PS51483; B5; 1;

Features [?]

From: SYFB_METTH (O26864)
Key From To Description Tag Condition FTGroup
BINDING 326 326 /ligand="Mg(2+)"
/ligand_id="ChEBI:CHEBI:18420"
/ligand_note="shared with alpha subunit"
[DEN]
BINDING 332 332 /ligand="Mg(2+)"
/ligand_id="ChEBI:CHEBI:18420"
/ligand_note="shared with alpha subunit"
[DE]
BINDING 335 335 /ligand="Mg(2+)"
/ligand_id="ChEBI:CHEBI:18420"
/ligand_note="shared with alpha subunit"
[DE]
BINDING 336 336 /ligand="Mg(2+)"
/ligand_id="ChEBI:CHEBI:18420"
/ligand_note="shared with alpha subunit"
[DEN]

Additional information [?]

Size range 515-604 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments Generally found in archaea, but also present in BORBU and TREPA.



View rule in raw text format (no links)