ExPASy Proteomics Server

Accession	MF_00151
Dates	1-JUN-2001 (Created) 25-NOV-2009 (Last updated, Version 21)

Data class

Protein

Predictors

HAMAP; MF_00151; [distribution of match scores in UniProtKB];[seed alignment for MF_00151]

Names

PPAT_bact

Identifier

COAD

Protein name

RecName: Full=Phosphopantetheine adenylyltransferase; EC=2.7.7.3; AltName: Full=Pantetheine-phosphate adenylyltransferase; Short=PPAT; AltName: Full=Dephospho-CoA pyrophosphorylase;

Gene name

coaD

FUNCTION: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity).

CATALYTIC ACTIVITY: ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA.

PATHWAY: Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.

SUBUNIT: Homohexamer (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the bacterial coaD family.

Pfam	PF01467; CTP_transf_2; 1;
PRINTS	PR01020; LPSBIOSNTHSS; 1;
TIGRFAMs	TIGR01510; coaD_prev_kdtB; 1; TIGR00125; cyt_tran_rel; 1;

ATP-binding, Coenzyme A biosynthesis, Cytoplasm, Nucleotide-binding, Nucleotidyltransferase, Transferase.

GO:0004595; Molecular function: pantetheine-phosphate adenylyltransferase activity.
GO:0015937; Biological process: coenzyme A biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Size range:	140-191 amino acids
Related UniRules:	None
Template:	P0A6I6 (COAD_ECOLI)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	Possible wrong start in ZYMMO