[1]
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NUCLEOTIDE SEQUENCE [MRNA] OF 7-592.
TISSUE=Hippocampus;
DOI=10.1111/j.1432-1033.1993.tb18179.x; PubMed=8375396 [NCBI, ExPASy, EBI, Israel, Japan]
Kochs G.,
Hummel R.,
Meyer D.,
Hug H.,
Marme D.,
Sarre T.F.;
"Activation and substrate specificity of the human protein kinase C alpha and zeta isoenzymes.";
Eur. J. Biochem. 216:597-606(1993).
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[2]
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NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Frontal cortex;
DOI=10.1016/0378-1119(93)90213-M; PubMed=8224878 [NCBI, ExPASy, EBI, Israel, Japan]
Barbee J.L.,
Loomis C.R.,
Deutscher S.L.,
Burns D.J.;
"The cDNA sequence encoding human protein kinase C-zeta.";
Gene 132:305-306(1993).
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[3]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Kalnine N.,
Chen X.,
Rolfs A.,
Halleck A.,
Hines L.,
Eisenstein S.,
Koundinya M.,
Raphael J.,
Moreira D.,
Kelley T.,
LaBaer J.,
Lin Y.,
Phelan M.,
Farmer A.;
"Cloning of human full-length CDSs in BD Creator(TM) system donor vector.";
Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
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[4]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nature04727; PubMed=16710414 [NCBI, ExPASy, EBI, Israel, Japan]
Gregory S.G.,
Barlow K.F.,
McLay K.E.,
Kaul R.,
Swarbreck D.,
Dunham A.,
Scott C.E.,
Howe K.L.,
Woodfine K.,
Spencer C.C.A.,
Jones M.C.,
Gillson C.,
Searle S.,
Zhou Y.,
Kokocinski F.,
McDonald L.,
Evans R.,
Phillips K.,
Atkinson A., ![]()
Cooper R.,
Jones C.,
Hall R.E.,
Andrews T.D.,
Lloyd C.,
Ainscough R.,
Almeida J.P.,
Ambrose K.D.,
Anderson F.,
Andrew R.W.,
Ashwell R.I.S.,
Aubin K.,
Babbage A.K.,
Bagguley C.L.,
Bailey J.,
Beasley H.,
Bethel G.,
Bird C.P.,
Bray-Allen S.,
Brown J.Y.,
Brown A.J.,
Buckley D.,
Burton J.,
Bye J.,
Carder C.,
Chapman J.C.,
Clark S.Y.,
Clarke G.,
Clee C.,
Cobley V.,
Collier R.E.,
Corby N.,
Coville G.J.,
Davies J.,
Deadman R.,
Dunn M.,
Earthrowl M.,
Ellington A.G.,
Errington H.,
Frankish A.,
Frankland J.,
French L.,
Garner P.,
Garnett J.,
Gay L.,
Ghori M.R.J.,
Gibson R.,
Gilby L.M.,
Gillett W.,
Glithero R.J.,
Grafham D.V.,
Griffiths C.,
Griffiths-Jones S.,
Grocock R.,
Hammond S.,
Harrison E.S.I.,
Hart E.,
Haugen E.,
Heath P.D.,
Holmes S.,
Holt K.,
Howden P.J.,
Hunt A.R.,
Hunt S.E.,
Hunter G.,
Isherwood J.,
James R.,
Johnson C.,
Johnson D.,
Joy A.,
Kay M.,
Kershaw J.K.,
Kibukawa M.,
Kimberley A.M.,
King A.,
Knights A.J.,
Lad H.,
Laird G.,
Lawlor S.,
Leongamornlert D.A.,
Lloyd D.M.,
Loveland J.,
Lovell J.,
Lush M.J.,
Lyne R.,
Martin S.,
Mashreghi-Mohammadi M.,
Matthews L.,
Matthews N.S.W.,
McLaren S.,
Milne S.,
Mistry S.,
Moore M.J.F.,
Nickerson T.,
O'Dell C.N.,
Oliver K.,
Palmeiri A.,
Palmer S.A.,
Parker A.,
Patel D.,
Pearce A.V.,
Peck A.I.,
Pelan S.,
Phelps K.,
Phillimore B.J.,
Plumb R.,
Rajan J.,
Raymond C.,
Rouse G.,
Saenphimmachak C.,
Sehra H.K.,
Sheridan E.,
Shownkeen R.,
Sims S.,
Skuce C.D.,
Smith M.,
Steward C.,
Subramanian S.,
Sycamore N.,
Tracey A.,
Tromans A.,
Van Helmond Z.,
Wall M.,
Wallis J.M.,
White S.,
Whitehead S.L.,
Wilkinson J.E.,
Willey D.L.,
Williams H.,
Wilming L.,
Wray P.W.,
Wu Z.,
Coulson A.,
Vaudin M.,
Sulston J.E.,
Durbin R.M.,
Hubbard T.,
Wooster R.,
Dunham I.,
Carter N.P.,
McVean G.,
Ross M.T.,
Harrow J.,
Olson M.V.,
Beck S.,
Rogers J.,
Bentley D.R.;
"The DNA sequence and biological annotation of human chromosome 1.";
Nature 441:315-321(2006).
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[5]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Colon, and Ovary;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[6]
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INTERACTION WITH SQSTM1, AND SUBCELLULAR LOCATION.
PubMed=9566925 [NCBI, ExPASy, EBI, Israel, Japan]
Sanchez P.,
De Carcer G.,
Sandoval I.V.,
Moscat J.,
Diaz-Meco M.T.;
"Localization of atypical protein kinase C isoforms into lysosome-targeted endosomes through interaction with p62.";
Mol. Cell. Biol. 18:3069-3080(1998).
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[7]
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PHOSPHORYLATION AT THR-410 BY PDPK1.
DOI=10.1016/S0960-9822(98)70444-0; PubMed=9768361 [NCBI, ExPASy, EBI, Israel, Japan]
Chou M.M.,
Hou W.,
Johnson J.,
Graham L.K.,
Lee M.H.,
Chen C.S.,
Newton A.C.,
Schaffhausen B.S.,
Toker A.;
"Regulation of protein kinase C zeta by PI 3-kinase and PDK-1.";
Curr. Biol. 8:1069-1077(1998).
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[8]
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INTERACTION WITH SQSTM1 AND IKBKB.
DOI=10.1093/emboj/18.11.3044; PubMed=10356400 [NCBI, ExPASy, EBI, Israel, Japan]
Sanz L.,
Sanchez P.,
Lallena M.-J.,
Diaz-Meco M.T.,
Moscat J.;
"The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation.";
EMBO J. 18:3044-3053(1999).
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[9]
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INTERACTION WITH PARD6A; PARD6B AND PARD6G.
TISSUE=Neuroblastoma;
DOI=10.1046/j.1365-2443.2001.00404.x; PubMed=11260256 [NCBI, ExPASy, EBI, Israel, Japan]
Noda Y.,
Takeya R.,
Ohno S.,
Naito S.,
Ito T.,
Sumimoto H.;
"Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C.";
Genes Cells 6:107-119(2001).
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[10]
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INTERACTION WITH SQSTM1 AND PAWR.
DOI=10.1016/S0014-5793(01)03224-0; PubMed=11755531 [NCBI, ExPASy, EBI, Israel, Japan]
Chang S.,
Kim J.H.,
Shin J.;
"p62 forms a ternary complex with PKCzeta and PAR-4 and antagonizes PAR-4-induced PKCzeta inhibition.";
FEBS Lett. 510:57-61(2002).
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[11]
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INTERACTION WITH PARD3.
DOI=10.1016/S0378-1119(02)00681-9; PubMed=12234671 [NCBI, ExPASy, EBI, Israel, Japan]
Gao L.,
Macara I.G.,
Joberty G.;
"Multiple splice variants of Par3 and of a novel related gene, Par3L, produce proteins with different binding properties.";
Gene 294:99-107(2002).
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[12]
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INTERACTION WITH ADAP1.
DOI=10.1016/S0006-291X(03)01187-2; PubMed=12893243 [NCBI, ExPASy, EBI, Israel, Japan]
Zemlickova E.,
Dubois T.,
Kerai P.,
Clokie S.,
Cronshaw A.D.,
Wakefield R.I.D.,
Johannes F.-J.,
Aitken A.;
"Centaurin-alpha(1) associates with and is phosphorylated by isoforms of protein kinase C.";
Biochem. Biophys. Res. Commun. 307:459-465(2003).
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[13]
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INTERACTION WITH SQSTM1 AND PARD6B, DOMAIN, AND MUTAGENESIS OF LYS-19; ASP-62 AND ASP-66.
DOI=10.1016/S1097-2765(03)00246-6; PubMed=12887891 [NCBI, ExPASy, EBI, Israel, Japan]
Wilson M.I.,
Gill D.J.,
Perisic O.,
Quinn M.T.,
Williams R.L.;
"PB1 domain-mediated heterodimerization in NADPH oxidase and signaling complexes of atypical protein kinase C with Par6 and p62.";
Mol. Cell 12:39-50(2003).
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[14]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-223, AND MASS SPECTROMETRY.
TISSUE=Epithelium;
DOI=10.1016/j.cell.2006.09.026; PubMed=17081983 [NCBI, ExPASy, EBI, Israel, Japan]
Olsen J.V.,
Blagoev B.,
Gnad F.,
Macek B.,
Kumar C.,
Mortensen P.,
Mann M.;
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.";
Cell 127:635-648(2006).
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[15]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-410, AND MASS SPECTROMETRY.
DOI=10.1016/j.molcel.2008.07.007; PubMed=18691976 [NCBI, ExPASy, EBI, Israel, Japan]
Daub H.,
Olsen J.V.,
Bairlein M.,
Gnad F.,
Oppermann F.S.,
Korner R.,
Greff Z.,
Keri G.,
Stemmann O.,
Mann M.;
"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.";
Mol. Cell 31:438-448(2008).
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[16]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-560, AND MASS SPECTROMETRY.
DOI=10.1073/pnas.0805139105; PubMed=18669648 [NCBI, ExPASy, EBI, Israel, Japan]
Dephoure N.,
Zhou C.,
Villen J.,
Beausoleil S.A.,
Bakalarski C.E.,
Elledge S.J.,
Gygi S.P.;
"A quantitative atlas of mitotic phosphorylation.";
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
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[17]
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IDENTIFICATION [LARGE SCALE ANALYSIS], AND MASS SPECTROMETRY.
Colinge J.,
Superti-Furga G.,
Bennett K.L.;
Submitted (OCT-2008) to UniProtKB.
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[18]
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VARIANT [LARGE SCALE ANALYSIS] PHE-514.
DOI=10.1126/science.1133427; PubMed=16959974 [NCBI, ExPASy, EBI, Israel, Japan]
Sjoeblom T.,
Jones S.,
Wood L.D.,
Parsons D.W.,
Lin J.,
Barber T.D.,
Mandelker D.,
Leary R.J.,
Ptak J.,
Silliman N.,
Szabo S.,
Buckhaults P.,
Farrell C.,
Meeh P.,
Markowitz S.D.,
Willis J.,
Dawson D.,
Willson J.K.V.,
Gazdar A.F., ![]()
Hartigan J.,
Wu L.,
Liu C.,
Parmigiani G.,
Park B.H.,
Bachman K.E.,
Papadopoulos N.,
Vogelstein B.,
Kinzler K.W.,
Velculescu V.E.;
"The consensus coding sequences of human breast and colorectal cancers.";
Science 314:268-274(2006).
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[19]
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VARIANTS [LARGE SCALE ANALYSIS] HIS-84 AND CYS-519.
DOI=10.1038/nature05610; PubMed=17344846 [NCBI, ExPASy, EBI, Israel, Japan]
Greenman C.,
Stephens P.,
Smith R.,
Dalgliesh G.L.,
Hunter C.,
Bignell G.,
Davies H.,
Teague J.,
Butler A.,
Stevens C.,
Edkins S.,
O'Meara S.,
Vastrik I.,
Schmidt E.E.,
Avis T.,
Barthorpe S.,
Bhamra G.,
Buck G.,
Choudhury B., ![]()
Clements J.,
Cole J.,
Dicks E.,
Forbes S.,
Gray K.,
Halliday K.,
Harrison R.,
Hills K.,
Hinton J.,
Jenkinson A.,
Jones D.,
Menzies A.,
Mironenko T.,
Perry J.,
Raine K.,
Richardson D.,
Shepherd R.,
Small A.,
Tofts C.,
Varian J.,
Webb T.,
West S.,
Widaa S.,
Yates A.,
Cahill D.P.,
Louis D.N.,
Goldstraw P.,
Nicholson A.G.,
Brasseur F.,
Looijenga L.,
Weber B.L.,
Chiew Y.-E.,
DeFazio A.,
Greaves M.F.,
Green A.R.,
Campbell P.,
Birney E.,
Easton D.F.,
Chenevix-Trench G.,
Tan M.-H.,
Khoo S.K.,
Teh B.T.,
Yuen S.T.,
Leung S.Y.,
Wooster R.,
Futreal P.A.,
Stratton M.R.;
"Patterns of somatic mutation in human cancer genomes.";
Nature 446:153-158(2007).
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