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UniProtKB/Swiss-Prot entry Q9ZDF6


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MAO2_RICPR
Primary accession number Q9ZDF6
Secondary accession numbers None
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on May 1, 1999 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 46)
Name and origin of the protein
Protein name Probable NADP-dependent malic enzyme
Synonyms NADP-ME
EC 1.1.1.40
Gene name
OrderedLocusNames: RP373
From
Rickettsia prowazekii [TaxID: 782] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales; Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Madrid E;
DOI=10.1038/24094; PubMed=9823893 [NCBI, ExPASy, EBI, Israel, Japan]
Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T., Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H., Kurland C.G.;
"The genome sequence of Rickettsia prowazekii and the origin of mitochondria.";
Nature 396:133-140(1998).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AJ235271; CAA14832.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR F71694; F71694.
RefSeq NP_220756.1; -.
3D structure databases
ModBase Q9ZDF6.
Enzyme and pathway databases
BioCyc RPRO272947:RP373-MON; -.
Family and domain databases
InterPro IPR015884; Malic_enzyme_CS.
IPR012301; Malic_N.
IPR012302; Malic_NAD_bd.
IPR012188; ME_PTA.
IPR002505; PTA_PTB.
Graphical view of domain structure.
Pfam PF00390; malic; 1.
PF03949; Malic_M; 1.
PF01515; PTA_PTB; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF036684; ME_PTA; 1.
PROSITE PS00331; MALIC_ENZYMES; 1.
BLOCKS Q9ZDF6.
Genome annotation databases
GeneID 883450; -.
GenomeReviews AJ235269_GR; RP373.
KEGG rpr:RP373; -.
Phylogenomic databases
HOGENOM Q9ZDF6; -.
Genome annotation databases
CMR Q9ZDF6; RP373.
Other
ProtoNet Q9ZDF6.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Metal-binding; Multifunctional enzyme; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   767  767     Probable NADP-dependent malic enzyme. PRO_0000160247
REGION   1   430  430     Malic enzyme. 
REGION   431   767  337     Phosphate acetyltransferase. 
ACT_SITE   97    97        Proton acceptor (By similarity). 
METAL   139   139        Divalent metal cation (By similarity). 
METAL   140   140        Divalent metal cation (By similarity). 
BINDING   165   165        NAD (By similarity). 
BINDING   290   290        NAD (By similarity). 
Sequence information
Length: 767 AA [This is the length of the unprocessed precursor] Molecular weight: 84253 Da [This is the MW of the unprocessed precursor] CRC64: 6782D33C85E30A5E [This is a checksum on the sequence]
        10         20         30         40         50         60 
MDEMNKINYT EALEYHEKDK PGKIAITTTK SLVTQQDLSL AYSPGVAAPC LEISKNLEAV 

        70         80         90        100        110        120 
YKYTSRSNLV AVISNGTAVL GLGNLGAAAS KPVMEGKAVL FKKFADIDAI DLEVNTEDPI 

       130        140        150        160        170        180 
EFINAVKYLG YSFGGINLED IKAPECFLIE EKLKSLMDIP VFHDDQHGTA IITAAGLINA 

       190        200        210        220        230        240 
AYLTNRTLKD LKIVINGAGA AAIACIDLLI ALGVDKSKII LCDTKGVIYK GRTSGMNKWK 

       250        260        270        280        290        300 
ERYASDTKIR TLTESLNNAD VFIGLSVKGA VTKDMISKMA HKPIIFAMAN PDPEITPEDI 

       310        320        330        340        350        360 
KFVRDDAIIA TGRSDYNNQV NNVMGFPYIF RGALDVRAST INTEMKIAAA RAIADLARRP 

       370        380        390        400        410        420 
VPEEVYKAYS GRKMVFGNEY IIPVPFDPRL ITVVATAVAV AAIESGVARV KDFSIDKYKQ 

       430        440        450        460        470        480 
QLGSRLNPTA NYMNFLAEKI HNVPLKRIVF AEGEEEEVIS AALMMRDEKY GNPIIIGRVE 

       490        500        510        520        530        540 
RIEVTLKKIG KDISLAGIQI MNAALSDRLE QYTDYLYKRL QRKGYLYRDC AKLVKTDKNI 

       550        560        570        580        590        600 
FAACMVACGD GDALLTGVTK SYIDSLEDII KVISPKQNRR ILGYSIMIAK DHNIIIADNC 

       610        620        630        640        650        660 
ITEYPNSLEL AQIATQTAEI AKNMGITPRV ALIAFSTFGN SSQEKTVRIR EAVNILDNFS 

       670        680        690        700        710        720 
KDKKKLNGIK VDFEYDGEMS VKVALDHDLR KLYQFCRLSG SANVLIMPGL NSAAISTELL 

       730        740        750        760 
QKFSSNSFIG PITNGFAKPV QILPTTATAN EILKIATFAC VEAIKEV 

Q9ZDF6 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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