[1]
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NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), CHARACTERIZATION, GLYCOSYLATION, TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
TISSUE=Pancreatic islet;
PubMed=10078553 [NCBI, ExPASy, EBI, Israel, Japan]
Arden S.D.,
Zahn T.,
Steegers S.,
Webb S.,
Bergman B.,
O'Brien R.M.,
Hutton J.C.;
"Molecular cloning of a pancreatic islet-specific glucose-6-phosphatase catalytic subunit-related protein.";
Diabetes 48:531-542(1999).
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[2]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=10078554 [NCBI, ExPASy, EBI, Israel, Japan]
Ebert D.H.,
Bischof L.J.,
Streeper R.S.,
Chapman S.C.,
Svitek C.A.,
Goldman J.K.,
Mathews C.E.,
Leiter E.H.,
Hutton J.C.,
O'Brien R.M.;
"Structure and promoter activity of an islet-specific glucose-6-phosphatase catalytic subunit-related gene.";
Diabetes 48:543-551(1999).
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[3]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
STRAIN=C57BL/6J;
TISSUE=Pancreas;
DOI=10.1126/science.1112014; PubMed=16141072 [NCBI, ExPASy, EBI, Israel, Japan]
Carninci P.,
Kasukawa T.,
Katayama S.,
Gough J.,
Frith M.C.,
Maeda N.,
Oyama R.,
Ravasi T.,
Lenhard B.,
Wells C.,
Kodzius R.,
Shimokawa K.,
Bajic V.B.,
Brenner S.E.,
Batalov S.,
Forrest A.R.,
Zavolan M.,
Davis M.J.,
Wilming L.G., ![]()
Aidinis V.,
Allen J.E.,
Ambesi-Impiombato A.,
Apweiler R.,
Aturaliya R.N.,
Bailey T.L.,
Bansal M.,
Baxter L.,
Beisel K.W.,
Bersano T.,
Bono H.,
Chalk A.M.,
Chiu K.P.,
Choudhary V.,
Christoffels A.,
Clutterbuck D.R.,
Crowe M.L.,
Dalla E.,
Dalrymple B.P.,
de Bono B.,
Della Gatta G.,
di Bernardo D.,
Down T.,
Engstrom P.,
Fagiolini M.,
Faulkner G.,
Fletcher C.F.,
Fukushima T.,
Furuno M.,
Futaki S.,
Gariboldi M.,
Georgii-Hemming P.,
Gingeras T.R.,
Gojobori T.,
Green R.E.,
Gustincich S.,
Harbers M.,
Hayashi Y.,
Hensch T.K.,
Hirokawa N.,
Hill D.,
Huminiecki L.,
Iacono M.,
Ikeo K.,
Iwama A.,
Ishikawa T.,
Jakt M.,
Kanapin A.,
Katoh M.,
Kawasawa Y.,
Kelso J.,
Kitamura H.,
Kitano H.,
Kollias G.,
Krishnan S.P.,
Kruger A.,
Kummerfeld S.K.,
Kurochkin I.V.,
Lareau L.F.,
Lazarevic D.,
Lipovich L.,
Liu J.,
Liuni S.,
McWilliam S.,
Madan Babu M.,
Madera M.,
Marchionni L.,
Matsuda H.,
Matsuzawa S.,
Miki H.,
Mignone F.,
Miyake S.,
Morris K.,
Mottagui-Tabar S.,
Mulder N.,
Nakano N.,
Nakauchi H.,
Ng P.,
Nilsson R.,
Nishiguchi S.,
Nishikawa S.,
Nori F.,
Ohara O.,
Okazaki Y.,
Orlando V.,
Pang K.C.,
Pavan W.J.,
Pavesi G.,
Pesole G.,
Petrovsky N.,
Piazza S.,
Reed J.,
Reid J.F.,
Ring B.Z.,
Ringwald M.,
Rost B.,
Ruan Y.,
Salzberg S.L.,
Sandelin A.,
Schneider C.,
Schoenbach C.,
Sekiguchi K.,
Semple C.A.,
Seno S.,
Sessa L.,
Sheng Y.,
Shibata Y.,
Shimada H.,
Shimada K.,
Silva D.,
Sinclair B.,
Sperling S.,
Stupka E.,
Sugiura K.,
Sultana R.,
Takenaka Y.,
Taki K.,
Tammoja K.,
Tan S.L.,
Tang S.,
Taylor M.S.,
Tegner J.,
Teichmann S.A.,
Ueda H.R.,
van Nimwegen E.,
Verardo R.,
Wei C.L.,
Yagi K.,
Yamanishi H.,
Zabarovsky E.,
Zhu S.,
Zimmer A.,
Hide W.,
Bult C.,
Grimmond S.M.,
Teasdale R.D.,
Liu E.T.,
Brusic V.,
Quackenbush J.,
Wahlestedt C.,
Mattick J.S.,
Hume D.A.,
Kai C.,
Sasaki D.,
Tomaru Y.,
Fukuda S.,
Kanamori-Katayama M.,
Suzuki M.,
Aoki J.,
Arakawa T.,
Iida J.,
Imamura K.,
Itoh M.,
Kato T.,
Kawaji H.,
Kawagashira N.,
Kawashima T.,
Kojima M.,
Kondo S.,
Konno H.,
Nakano K.,
Ninomiya N.,
Nishio T.,
Okada M.,
Plessy C.,
Shibata K.,
Shiraki T.,
Suzuki S.,
Tagami M.,
Waki K.,
Watahiki A.,
Okamura-Oho Y.,
Suzuki H.,
Kawai J.,
Hayashizaki Y.;
"The transcriptional landscape of the mammalian genome.";
Science 309:1559-1563(2005).
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[4]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=C57BL/6J;
The mouse genome sequencing consortium;
Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
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[5]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[6]
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TISSUE SPECIFICITY.
DOI=10.1016/S0006-291X(03)01242-7; PubMed=12878201 [NCBI, ExPASy, EBI, Israel, Japan]
Goh B.-H.,
Efendic S.,
Khan A.,
Portwood N.;
"Evidence for the expression of both the hydrolase and translocase components of hepatic glucose-6-phosphatase in murine pancreatic islets.";
Biochem. Biophys. Res. Commun. 307:935-941(2003).
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[7]
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IDENTIFICATION BY MASS SPECTROMETRY, AND IDENTIFICATION AS AN AUTOANTIGEN.
DOI=10.1073/pnas.0932778100; PubMed=12815107 [NCBI, ExPASy, EBI, Israel, Japan]
Lieberman S.M.,
Evans A.M.,
Han B.,
Takaki T.,
Vinnitskaya Y.,
Caldwell J.A.,
Serreze D.V.,
Shabanowitz J.,
Hunt D.F.,
Nathenson S.G.,
Santamaria P.,
DiLorenzo T.P.;
"Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.";
Proc. Natl. Acad. Sci. U.S.A. 100:8384-8388(2003).
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[8]
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CATALYTIC ACTIVITY, INDUCTION, AND TISSUE SPECIFICITY.
DOI=10.1074/jbc.M307756200; PubMed=14722102 [NCBI, ExPASy, EBI, Israel, Japan]
Petrolonis A.J.,
Yang Q.,
Tummino P.J.,
Fish S.M.,
Prack A.E.,
Jain S.,
Parsons T.F.,
Li P.,
Dales N.A.,
Ge L.,
Langston S.P.,
Schuller A.G.P.,
An W.F.,
Tartaglia L.A.,
Chen H.,
Hong S.-B.;
"Enzymatic characterization of the pancreatic islet-specific glucose-6-phosphatase-related protein (IGRP).";
J. Biol. Chem. 279:13976-13983(2004).
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[9]
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IDENTIFICATION AS AN AUTOANTIGEN.
PubMed=15843527 [NCBI, ExPASy, EBI, Israel, Japan]
Mukherjee R.,
Wagar D.,
Stephens T.A.,
Lee-Chan E.,
Singh B.;
"Identification of CD4+ T cell-specific epitopes of islet-specific glucose-6-phosphatase catalytic subunit-related protein: a novel beta cell autoantigen in type 1 diabetes.";
J. Immunol. 174:5306-5315(2005).
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[10]
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KNOCKOUT.
DOI=10.1007/s00125-006-0564-1; PubMed=17265032 [NCBI, ExPASy, EBI, Israel, Japan]
Wang Y.,
Martin C.C.,
Oeser J.K.,
Sarkar S.,
McGuinness O.P.,
Hutton J.C.,
O'Brien R.M.;
"Deletion of the gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen results in a mild metabolic phenotype.";
Diabetologia 50:774-778(2007).
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