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UniProtKB/Swiss-Prot entry Q9YAI1

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NADE_AERPE
Primary accession number Q9YAI1
Secondary accession numbers None
Integrated into Swiss-Prot on December 1, 2000
Sequence was last modified on July 10, 2007 (Sequence version 3)
Annotations were last modified on    November 25, 2008 (Entry version 48)
Name and origin of the protein
Protein name Probable NH(3)-dependent NAD(+) synthetase
Synonym EC 6.3.1.5
Gene name
Name: nadE
OrderedLocusNames: APE_1958.1
From
Aeropyrum pernix [TaxID: 56636] [HAMAP proteome]
Taxonomy Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales; Desulfurococcaceae; Aeropyrum.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K1;
DOI=10.1093/dnares/6.2.83; PubMed=10382966 [NCBI, ExPASy, EBI, Israel, Japan]
Kawarabayasi Y., Hino Y., Horikawa H., Yamazaki S., Haikawa Y., Jin-no K., Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A., Fukui S., Nagai Y., Nishijima K., Nakazawa H., Takamiya M., Masuda S., Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Kubota K., Nakamura Y., Nomura N., Sako Y., Kikuchi H.;
"Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1.";
DNA Res. 6:83-101(1999).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000002; BAA80968.2; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR H72497; H72497.
RefSeq NP_148287.2; -.
3D structure databases
HSSP P08164; 1IH8. [HSSP ENTRY / PDB]
ModBase Q9YAI1.
Ontologies
GO
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0003952; Molecular function: NAD+ synthase (glutamine-hydrolyzing) activity (inferred from electronic annotation from InterPro).
GO:0008795; Molecular function: NAD+ synthase activity (inferred from electronic annotation from EC).
GO:0009435; Biological process: NAD biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00193; -; 1.
PBIL [Tree]
InterPro IPR003694; NAD_synthase.
Graphical view of domain structure.
Pfam PF02540; NAD_synthase; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00552; nadE; 1.
ProtoNet Q9YAI1.
Genome annotation databases
GeneID 1446370; -.
GenomeReviews BA000002_GR; APE_1958.1.
KEGG ape:APE_1958.1; -.
NMPDR fig|272557.1.peg.1395; -.
Phylogenomic databases
HOGENOM Q9YAI1; -.
Genome annotation databases
CMR Q9YAI1; APE_1958.1.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Complete proteome; Ligase; NAD; Nucleotide-binding.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
CHAIN   1   286  286     Probable NH(3)-dependent NAD(+) synthetase. PRO_0000152220
NP_BIND   43    50  8     ATP (By similarity). 
ACT_SITE   45    45        By similarity. 
Sequence information
Length: 286 AA [This is the length of the unprocessed precursor] Molecular weight: 31771 Da [This is the MW of the unprocessed precursor] CRC64: 0AAC3C82688B1CE0 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAVNYKVSLD DVVDIDYNGV RQAITQFLRK YLEASGASGY VLGVSGGVDS SLALALAVDA 

        70         80         90        100        110        120 
VGSGRVTALI MPDREVTPER DVEDALRLVR SFGVEHAVID ISPIVMVYIS ALPIFEDEEK 

       130        140        150        160        170        180 
DRVPVGNLRA RIRANILYYY ANKLGKLVLG TGDRSEYLIG YFTKYGDAAC DVAPLTVLYK 

       190        200        210        220        230        240 
SQVRRLAELI GVPRDIAYKP SSPRLWKGHE AEAELGLSYN EIDVILYSRF DLKIPWEEIP 

       250        260        270        280 
RATGLERAKV ERVRLLHEAS SHKRSPPASP DLGEIKKHYK QHAGKK
Q9YAI1 in FASTA format

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