ID   Q9V4B8_DROME            Unreviewed;       917 AA.
AC   Q9V4B8;
DT   01-MAY-2000, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 3.
DT   02-SEP-2008, entry version 66.
DE   SubName: Full=CG31999-PA (RE68558p);
GN   Name=CG10323; ORFNames=CG31999, Dmel_CG31999;
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   MEDLINE=22426069; PubMed=12537572;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q.,
RA   Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M.,
RA   Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a
RT   systematic review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   MEDLINE=20196006; PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X.,
RA   Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D.,
RA   Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G.,
RA   Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D.,
RA   Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M.,
RA   Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S.,
RA   Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P.,
RA   Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I.,
RA   Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P.,
RA   de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M.,
RA   Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P.,
RA   Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W.,
RA   Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K.,
RA   Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J.,
RA   Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C.,
RA   Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A.,
RA   Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z.,
RA   Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X.,
RA   Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D.,
RA   Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A.,
RA   Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L.,
RA   Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M.,
RA   Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G.,
RA   Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H.,
RA   Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E.,
RA   Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X.,
RA   Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J.,
RA   Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A.,
RA   Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L.,
RA   Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X.,
RA   Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [3]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Berkeley;
RA   Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J.,
RA   Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E.,
RA   George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G.,
RA   Miranda A., Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S.,
RA   Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M.,
RA   Celniker S.;
RL   Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- INTERACTION:
CC       Q9VL20:-; NbExp=1; IntAct=EBI-145217, EBI-149685;
CC       O46197:Acp29AB; NbExp=1; IntAct=EBI-145217, EBI-153710;
CC       Q9Y130:BcDNA.GH07485; NbExp=1; IntAct=EBI-145217, EBI-128385;
CC       P25171:Bj1; NbExp=1; IntAct=EBI-145217, EBI-181948;
CC       Q9V5X2:CG7745; NbExp=1; IntAct=EBI-145217, EBI-149162;
CC       Q9V3G9:EG:BACR37P7.5; NbExp=1; IntAct=EBI-145217, EBI-162998;
CC       Q8IN81-10:fru; NbExp=1; IntAct=EBI-145217, EBI-196831;
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DR   EMBL; AE014135; AAF59360.3; -; Genomic_DNA.
DR   EMBL; BT003472; AAO39475.1; -; mRNA.
DR   RefSeq; NP_726551.2; -.
DR   UniGene; Dm.33082; -.
DR   HSSP; Q9UCV4; 1NZI.
DR   IntAct; Q9V4B8; -.
DR   Ensembl; CG31999; Drosophila melanogaster.
DR   GeneID; 43777; -.
DR   KEGG; dme:Dmel_CG31999; -.
DR   NMPDR; fig|7227.3.peg.8364; -.
DR   FlyBase; FBgn0051999; CG31999.
DR   HOGENOM; Q9V4B8; -.
DR   ArrayExpress; Q9V4B8; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   InterPro; IPR006210; EGF.
DR   InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_CS.
DR   InterPro; IPR000742; EGF_3.
DR   InterPro; IPR001881; EGF_Ca_bd.
DR   InterPro; IPR013091; EGF_Ca_bd_2.
DR   InterPro; IPR013032; EGF_like_reg_CS.
DR   Pfam; PF07645; EGF_CA; 10.
DR   SMART; SM00181; EGF; 3.
DR   SMART; SM00179; EGF_CA; 6.
DR   PROSITE; PS00010; ASX_HYDROXYL; 6.
DR   PROSITE; PS01186; EGF_2; 4.
DR   PROSITE; PS50026; EGF_3; 7.
DR   PROSITE; PS01187; EGF_CA; 10.
PE   1: Evidence at protein level;
KW   Complete proteome; EGF-like domain; Repeat.
SQ   SEQUENCE   917 AA;  102100 MW;  23F6A8373A7A0614 CRC64;
     MFYKLCAFMC FLIVGGHVTT TMASDSISGY IRKCCINGLR HARTTASCKK IDIAPTIIPQ
     LWLGLCHSTL EVCCSRELDH QDCELGRLAA LDGTRCDGEG NVTSSSYATC CRSCQIGLAV
     KASKANCKDP LFSFIFLIES YRACCYGSAD FKDQPGIDEI DKANSITDEG ELPFVSEEDM
     NVTIVLTGDD DICGKIENLC AHICENTFDA YQCKCHPGFM LDNNNVTCSP MKTQICPSGY
     NLDKLDNKCI DIDECREDLH DCKSSQYCHN TNGGYHCLNV KEKECPPGFH YDHDYDACKD
     DYKCKDRKCV KIQSCDKGFS LHNGTCSDID ECSHKSLNNC HVNSNQECVN TVGSYSCNCL
     PGFNLDATLN KCVDINECSI NNHNCLPTQR CDNTIGSYIC TRLQSCGTGY TLNAETGNCD
     DDDECTLSTH NCPSNYDCHN TRGSFRCYRK ISTMLTTRTT STTVPPLSLE NARRSFTSRY
     PYPLAVHPEY SQNNDSISTN RRVDCSPGFY RNTLGACIDT NECMEQNPCG NHERCINTNG
     HFRCESLLQC SPGYKSTVDG KSCIDIDECD TGEHNCGERQ ICRNRNGGFV CSCPIGHELK
     RSIGGASTCV DTNECALEQR VCPLNAQCFN TIGAYYCECK AGFQKKSDGN NSTQCFDIDE
     CQVIPGLCQQ KCLNFWGGYR CTCNSGYQLG PDNRTCNDIN ECEVHKDYKL CMGLCINTPG
     SYQCSCPRGY ILAADMNTCR DVDECATDSI NQVCTGRNDI CTNIRGSYKC TTVNCPLGYS
     IDPEQKNRCR QNLNFCEGEE CYTQPSAFTY NFITFVSKLM IPPDGRTIFT LRGPLWYDNI
     EFDLKIVRIQ ATTNIQKATD GSFDTLQNNN QVNVILKKSL EGPQDIELEL SMTVYTNGMP
     RGKSVAKLFL FVSQHTF
//