NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Kim Y.-K., Kolattukudy P.E.;
"Identification of a ubiquitin-conjugating enzyme of the rice blast fungus Magnaporthe grisea.";
Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases.

[2]

NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=70-15 / FGSC 8958;
DOI=10.1038/nature03449; PubMed=15846337 [NCBI, ExPASy, EBI, Israel, Japan]
Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K., Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D., Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S., Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M., Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E., Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W.;
"The genome sequence of the rice blast fungus Magnaporthe grisea.";
Nature 434:980-986(2005).

Comments

FUNCTION: Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity).
CATALYTIC ACTIVITY: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
PATHWAY: Protein modification; protein ubiquitination .
SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AF161722; AAD55983.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
CH476833; EDK00488.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

XP_370047.2; -.

3D structure databases

HSSP

P15731; 1QCQ. [HSSP ENTRY / PDB]

SMR

Q9UVR2; 1-147.

ModBase

Q9UVR2.

Family and domain databases

InterPro

IPR016135; UBQ-conjugat/RWD-like.
IPR000608; UBQ-conjugat_E2.
Graphical view of domain structure.

Gene3D

G3DSA:3.10.110.10; UBQ-conjugat_E2; 1.

PANTHER

PTHR11621; UBQ-conjugat_E2; 1.

Pfam

PF00179; UQ_con; 1.
Pfam graphical view of domain structure.

ProDom

PD000461; UBQ_conjugat; 1.
[Domain structure / List of seq. sharing at least 1 domain]

SMART

SM00212; UBCc; 1.
SMART graphical view of domain structure.

PROSITE

PS00183; UBIQUITIN_CONJUGAT_1; 1.
PS50127; UBIQUITIN_CONJUGAT_2; 1.
PROSITE graphical view of domain structure (profiles).

BLOCKS

Q9UVR2.

Genome annotation databases

GeneID

2684717; -.

KEGG

mgr:MGG_06562; -.

Other

Q9UVR2; -.

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Ligase; Ubl conjugation pathway.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 147`	`147`	`Ubiquitin-conjugating enzyme E2-16 kDa.`	`PRO_0000082543`
`ACT_SITE`	`107 107`		`Glycyl thioester intermediate (By similarity).`
`CONFLICT`	`128 128`		`K -> R (in Ref. 1; AAD55983).`
`CONFLICT`	`136 136`		`S -> A (in Ref. 1; AAD55983).`
`CONFLICT`	`143 143`		`R -> P (in Ref. 1; AAD55983).`

Sequence information

Length: 147 AA [This is the length of the unprocessed precursor]

Molecular weight: 16438 Da [This is the MW of the unprocessed precursor]

CRC64: C7737C95FB7F61F7 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MALKRINKEL TDLGRDPPSS CSAGPVGEDL FHWQATIMGP SDSPYAGGVF FLAIHFPTDY 

        70         80         90        100        110        120 
PFKPPKVNFT TRIYHPNINS NGSICLDILR DQWSPALTIS KVLLSICSML TDPNPDDPLV 

       130        140 
PEIAHVYKTA RAQYESTARE WTRKYAI

Q9UVR2 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools