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UniProtKB/Swiss-Prot entry Q9UPU6

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ZN409_HUMAN
Primary accession number Q9UPU6
Secondary accession numbers None
Integrated into Swiss-Prot on February 12, 2003
Sequence was last modified on May 1, 2000 (Sequence version 1)
Annotations were last modified on    June 16, 2009 (Entry version 57)
Name and origin of the protein
Protein name Zinc finger protein 409
Synonyms None
Gene name
Name: ZNF409
Synonyms: KIAA1056
From
Homo sapiens (Human) [TaxID: 9606] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Brain;
DOI=10.1093/dnares/6.3.197; PubMed=10470851 [NCBI, ExPASy, EBI, Israel, Japan]
Kikuno R., Nagase T., Ishikawa K., Hirosawa M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.;
"Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.";
DNA Res. 6:197-205(1999).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AB028979; BAA83008.2; ALT_INIT; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
IPI IPI00007109; -.
UniGene Hs.508937
3D structure databases
HSSP P15822; 3ZNF. [HSSP ENTRY / PDB]
ModBase Q9UPU6.
PTM databases
PhosphoSite Q9UPU6; -.
Organism-specific databases
GeneCards GC14M023069; -.
GC14U900909; -.
HGNC HGNC:20042; ZNF409.
GenAtlas ZNF409.
HPA HPA005146; -.
PharmGKB PA142670520; -.
HUGE KIAA1056.
Gene expression databases
Bgee Q9UPU6; -.
CleanEx HS_ZNF409; -.
GermOnline ENSG00000206083; Homo sapiens.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from direct assay from HPA).
GO:0005634; Cellular component: nucleus (inferred from direct assay from HPA).
GO:0003677; Molecular function: DNA binding (inferred from electronic annotation from UniProtKB-KW).
GO:0008270; Molecular function: zinc ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0006355; Biological process: regulation of transcription, DNA-dependent (inferred from electronic annotation from UniProtKB-KW).
GO:0006350; Biological process: transcription (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR007087; Znf_C2H2.
IPR015880; Znf_C2H2-like.
IPR013087; Znf_C2H2/integrase_DNA-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.30.160.60; Znf_C2H2/integrase_DNA-bd; 1.
Pfam PF00096; zf-C2H2; 2.
Pfam graphical view of domain structure.
SMART SM00355; ZnF_C2H2; 6.
SMART graphical view of domain structure.
PROSITE PS00028; ZINC_FINGER_C2H2_1; 2.
PS50157; ZINC_FINGER_C2H2_2; FALSE_NEG.
PROSITE graphical view of domain structure (profiles).
Proteomic databases
PRIDE Q9UPU6; -.
Genome annotation databases
Ensembl ENSG00000206083; Homo sapiens. [Contig view]
Phylogenomic databases
HOGENOM Q9UPU6; -.
HOVERGEN Q9UPU6; -.
Other
ProtoNet Q9UPU6.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
DNA-binding; Metal-binding; Nucleus; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   862  862     Zinc finger protein 409. PRO_0000047570
ZN_FING   237   259  23     C2H2-type 1. 
ZN_FING   453   476  24     C2H2-type 2. 
ZN_FING   508   532  25     C2H2-type 3. 
ZN_FING   569   593  25     C2H2-type 4. 
ZN_FING   758   782  25     C2H2-type 5. 
ZN_FING   821   845  25     C2H2-type 6. 
COMPBIAS   605   710  106     Pro-rich. 
Sequence information
Length: 862 AA [This is the length of the unprocessed precursor] Molecular weight: 91802 Da [This is the MW of the unprocessed precursor] CRC64: EB6BFF9A0B939217 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MATLNSASTT GTTPSPGHNA PSLPSDTFSS STPSDPVTKD PPAASSTSEN MRSSEPGGQL 

        70         80         90        100        110        120 
LESGCGLVPP KEIGEPQEGP DCGHFPPNDP GVEKDKEQEE EEEGLPPMDL SNHLFFTAGG 

       130        140        150        160        170        180 
EAYLVAKLSL PGGSELLLPK GFPWGEAGIK EEPSLPFLAY PPPSHLTALH IQHGFDPIQG 

       190        200        210        220        230        240 
FSSSDQILSH DTSAPSPAAC EERHGAFWSY QLAPNPPGDP KDGPMGNSGG NHVAVFWLCL 

       250        260        270        280        290        300 
LCRLGFSKPQ AFMDHTQSHG VKLTPAQYQG LSGSPAVLQE GDEGCKALIS FLEPKLPARP 

       310        320        330        340        350        360 
SSDIPLDNSS TVNMEANVAQ TEDGPPEAEV QALILLDEEV MALSPPSPPT ATWDPSPTQA 

       370        380        390        400        410        420 
KESPVAAGEA GPDWFPEGQE EDGGLCPPLN QSSPTSKEGG TLPAPVGSPE DPSDPPQPYR 

       430        440        450        460        470        480 
LADDYTPAPA AFQGLSLSSH MSLLHSRNSC KTLKCPKCNW HYKYQQTLDV HMQEKHPESN 

       490        500        510        520        530        540 
SHCSYCSAGG AHPRLARGES YNCGYKPYRC DVCNYSTTTK GNLSIHMQSD KHLANLQGFQ 

       550        560        570        580        590        600 
AGPGGQGSPT EASLPPSAGD KEPKTKSSWQ CKVCSYETNI SRNLRIHMTS EKHMQNVLML 

       610        620        630        640        650        660 
HQGLPLGLPP GLMGPGPPPP PGATPTSPPE LFQYFGPQAL GQPQTPLAGP GLRPDKPLEA 

       670        680        690        700        710        720 
QLLLNGFHHV GAPARKFPTS APGSLSPDAH LPPSQLLGSS SDSLPTSPPP DDSLSLKVFR 

       730        740        750        760        770        780 
CLVCQAFSTD SLELLLYHCS IGRSLPEAEW KEVAGDTHRC KLCCYGTQLK ANFQLHLKTD 

       790        800        810        820        830        840 
KHAQKYQLAA HLREGGGAMG TPSPASLGDG APYGSVSPLH LRCNICDFES NSKEKMQLHA 

       850        860 
RGAAHEENSQ IYKRTETGLL IK
Q9UPU6 in FASTA format

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