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UniProtKB/Swiss-Prot entry Q9S2F4


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HPPD_STRCO
Primary accession number Q9S2F4
Secondary accession numbers None
Integrated into Swiss-Prot on December 6, 2005
Sequence was last modified on May 1, 2000 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 43)
Name and origin of the protein
Protein name 4-hydroxyphenylpyruvate dioxygenase
Synonyms HPPDase
4HPPD
HPD
EC 1.13.11.27
Gene name
Name: hpd
OrderedLocusNames: SCO2927
ORFNames: SCE19A.27c
From
Streptomyces coelicolor [TaxID: 1902] [HAMAP proteome]
Taxonomy Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Streptomycineae; Streptomycetaceae; Streptomyces.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC BAA-471 / A3(2) / M145;
DOI=10.1038/417141a; PubMed=12000953 [NCBI, ExPASy, EBI, Israel, Japan]
Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L., Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.-H., Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E., Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D., Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A.;
"Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).";
Nature 417:141-147(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL939114; CAB51008.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T36150; T36150.
RefSeq NP_627153.1; -.
3D structure databases
HSSP P80064; 1CJX. [HSSP ENTRY / PDB]
SMR Q9S2F4; 16-377.
ModBase Q9S2F4.
Enzyme and pathway databases
BioCyc SCOE100226:SCO2927-MON; -.
Family and domain databases
InterPro IPR005956; 4OHPhenylPyrv_dOase.
IPR004360; Glyas_bleo-R_dOase.
Graphical view of domain structure.
PANTHER PTHR11959; HPP_dOase; 1.
Pfam PF00903; Glyoxalase; 2.
Pfam graphical view of domain structure.
PIRSF PIRSF009283; HPP_dOase; 1.
TIGRFAMs TIGR01263; 4HPPD; 1.
BLOCKS Q9S2F4.
Genome annotation databases
GeneID 1098360; -.
GenomeReviews AL645882_GR; SCO2927.
KEGG sco:SCO2927; -.
NMPDR fig|100226.1.peg.2889; -.
Phylogenomic databases
HOGENOM Q9S2F4; -.
Genome annotation databases
CMR Q9S2F4; SCO2927.
Other
ProtoNet Q9S2F4.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Dioxygenase; Iron; Metal-binding; Oxidoreductase; Phenylalanine catabolism; Tyrosine catabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   381  381     4-hydroxyphenylpyruvate dioxygenase. PRO_0000088410
METAL   187   187        Iron (By similarity). 
METAL   270   270        Iron (By similarity). 
METAL   349   349        Iron (By similarity). 
Sequence information
Length: 381 AA [This is the length of the unprocessed precursor] Molecular weight: 41876 Da [This is the MW of the unprocessed precursor] CRC64: 326B241FF9BAC49E [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTQTTHHTPD TARQADPFPV KGMDAVVFAV GNAKQAAHYY STAFGMKLVA YSGPENGSRE 

        70         80         90        100        110        120 
TASYVLESGS ARFVFTSVIK PSTDWGTFLA QHVAEHGDGV VDLAIEVPDA RAAHAYAVEH 

       130        140        150        160        170        180 
GARSLAEPHE VKDEHGTVVL AAIATYGETR HTLVERTGYD GPYLPGYVAA KPMVAPPAQR 

       190        200        210        220        230        240 
VFQAVDHCVG NVELGRMNEW VGFYNKVMGF TNMKEFVGDD IATEYSALMS KVVADGTLKV 

       250        260        270        280        290        300 
KFPINEPAIA KKKSQIDEYL EFYGGAGVQH IALNTNDIVA TVRAMRAAGV EFLDTPDSYY 

       310        320        330        340        350        360 
DTLGEWAGET RVPVDVLREL KILVDRDEDG YLLQIFTKPV QDRPTVFFEM IERHGSMGFG 

       370        380 
KGNFKALFEA IEREQEKRGN L 

Q9S2F4 in FASTA format

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