NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=OH4384 / Serotype O:19;
Gilbert M., Michniewicz J., Wakarchuk W.W.;
"Cloning of a multidrug-efflux transporter homolog from Campylobacter jejuni.";
Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.

[2]

NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=NCTC 11168 / Serotype O:2;
DOI=10.1038/35001088; PubMed=10688204 [NCBI, ExPASy, EBI, Israel, Japan]
Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A., Rajandream M.A., Rutherford K.M., van Vliet A.H.M., Whitehead S., Barrell B.G.;
"The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences.";
Nature 403:665-668(2000).

Comments

FUNCTION: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions (By similarity).
CATALYTIC ACTIVITY: NTP + H₂O = NDP + phosphate.
COFACTOR: Divalent cations (By similarity).
SUBUNIT: Homodimer (By similarity).
SIMILARITY: Belongs to the HAM1 NTPase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AF113952; AAD10059.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
AL111168; CAL35486.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

C81282; C81282.

3D structure databases

HSSP

Q57679; 1B78. [HSSP ENTRY / PDB]

ModBase

Q9PMS6.

Enzyme and pathway databases

BioCyc

CJEJ192222:CJ1374C-MON; -.

Ontologies

GO:0017111;	Molecular function: nucleoside-triphosphatase activity (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_01405; -; 1.
PBIL [Tree]

InterPro

IPR002637; Ham1p_like.
Graphical view of domain structure.

PANTHER

PTHR11067; Ham1p_like; 1.

Pfam

PF01725; Ham1p_like; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR00042; Ham1p_like; 1.

BLOCKS

Q9PMS6.

Genome annotation databases

GenomeReviews

AL111168_GR; Cj1374c.

KEGG

cje:Cj1374c; -.

CMR

Q9PMS6; Cj1374c.

Other

ProtoNet

Q9PMS6.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Hydrolase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 200`	`200`	`Nucleoside-triphosphatase.`	`PRO_0000178145`
`CONFLICT`	`120 120`		`Y -> H (in Ref. 1; AAD10059).`

Sequence information

Length: 200 AA [This is the length of the unprocessed precursor]

Molecular weight: 22375 Da [This is the MW of the unprocessed precursor]

CRC64: 02F29AF6FEB0FBA1 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKIILATSNK HKVLELKEIL KDFEIYAFDE VLMPFEIEEN GKTFKENALI KARAVFNALD 

        70         80         90        100        110        120 
EKQKKDFIAL SDDSGICVDV LEGNPGIYSA RFSGKGDDKS NRDKLVNEMI KKGFKQSKAY 

       130        140        150        160        170        180 
YVAAIAMVGL MGEFSTHGTM HGKVIDTEKG ENGFGYDSLF IPKGFDKTLA QLSVDEKNNI 

       190        200 
SHRFKALELA KIILKILNKG

Q9PMS6 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools