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UniProtKB/Swiss-Prot entry Q9PLG5

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MURD_CHLMU
Primary accession number Q9PLG5
Secondary accession numbers None
Integrated into Swiss-Prot on April 30, 2003
Sequence was last modified on April 30, 2003 (Sequence version 2)
Annotations were last modified on    November 25, 2008 (Entry version 55)
Name and origin of the protein
Protein name UDP-N-acetylmuramoylalanine--D-glutamate ligase
Synonyms EC 6.3.2.9
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
D-glutamic acid-adding enzyme
Gene name
Name: murD
OrderedLocusNames: TC_0139
From
Chlamydia muridarum [TaxID: 83560] [HAMAP proteome]
Taxonomy Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae; Chlamydia.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=MoPn / Nigg;
DOI=10.1093/nar/28.6.1397; PubMed=10684935 [NCBI, ExPASy, EBI, Israel, Japan]
Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J., Gwinn M.L., Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M.;
"Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39.";
Nucleic Acids Res. 28:1397-1406(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE002160; AAF39017.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR F81736; F81736.
RefSeq NP_296518.1; -.
3D structure databases
HSSP P14900; 1EEH. [HSSP ENTRY / PDB]
ModBase Q9PLG5.
Enzyme and pathway databases
BioCyc CMUR243161:TC_0139-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0004665; Molecular function: prephenate dehydrogenase (NADP+) activity (inferred from electronic annotation from InterPro).
GO:0008764; Molecular function: UDP-N-acetylmuramoylalanine-D-glutamate ligase activity (inferred from electronic annotation from HAMAP).
GO:0007049; Biological process: cell cycle (inferred from electronic annotation from UniProtKB-KW).
GO:0051301; Biological process: cell division (inferred from electronic annotation from InterPro).
GO:0009252; Biological process: peptidoglycan biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0008360; Biological process: regulation of cell shape (inferred from electronic annotation from InterPro).
GO:0006571; Biological process: tyrosine biosynthetic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
HAMAP MF_00639; -; 1.
PBIL [Tree]
InterPro IPR004101; Mur_ligase_C.
IPR013221; Mur_ligase_cen.
IPR016040; NAD(P)-bd.
IPR003099; Prephen_DHase.
IPR005762; UDP-N-AcMur-Glu_ligase.
Graphical view of domain structure.
Gene3D G3DSA:3.90.190.20; Mur_ligase_C; 1.
G3DSA:3.40.1190.10; Mur_ligase_cen; 1.
G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF02875; Mur_ligase_C; 1.
PF08245; Mur_ligase_M; 1.
PF02153; PDH; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01087; murD; 1.
ProtoNet Q9PLG5.
Genome annotation databases
GeneID 1245673; -.
GenomeReviews AE002160_GR; TC_0139.
KEGG cmu:TC0139; -.
TIGR TC_0139; -.
Phylogenomic databases
HOGENOM Q9PLG5; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Cell cycle; Cell division; Cell shape; Cell wall biogenesis/degradation; Complete proteome; Cytoplasm; Ligase; Nucleotide-binding; Peptidoglycan synthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   416  416     UDP-N-acetylmuramoylalanine--D-glutamate ligase. PRO_0000108992
NP_BIND   108   114  7     ATP (Potential). 
Sequence information
Length: 416 AA [This is the length of the unprocessed precursor] Molecular weight: 46265 Da [This is the MW of the unprocessed precursor] CRC64: 0F7C4879B3EDC8D3 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MGLKRVVVIG LGLSGKSIAR FLARKGVYVL GVDSSIQALQ HCPYIHEKLL ETDEFPTQVD 

        70         80         90        100        110        120 
YVVRSPGISK DHPWVKAARA AQISVVTDIQ LAFQTKEFIE QKSFGITGTV GKTTTILFLE 

       130        140        150        160        170        180 
YLLRKAGIPA FAMGNVGVPI LDGMQNSGVR LVEMSSFQLA DQETSYPVLS GGMILNISDN 

       190        200        210        220        230        240 
HLDYHGSFLE YCQSKQNLSL CMRNPEDLWV GDQRFCGRSY WEEVQKYMRL LDKESALKPL 

       250        260        270        280        290        300 
YLHDKYNYCC AYLLAQAEFP IAKSLFIEAV ATFKKPSHRM EYLGEKCGVH YINDSKATTV 

       310        320        330        340        350        360 
RATEKALLSI GSRAIVILGG RNKGYSFVSL LPSLRRFAKS VVAMGECAQE IAQDLDGFPV 

       370        380        390        400        410 
TVVRNLHEAL LCAEEQAIPG DVVLLSPACA SFDQFRSYEE RGAIFKQLVG MEEVLL
Q9PLG5 in FASTA format

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