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UniProtKB/Swiss-Prot entry Q9P7X1


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MPPB_SCHPO
Primary accession number Q9P7X1
Secondary accession number P78803
Integrated into Swiss-Prot on April 11, 2003
Sequence was last modified on October 1, 2000 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 45)
Name and origin of the protein
Protein name Probable mitochondrial-processing peptidase subunit beta [Precursor]
Synonyms EC 3.4.24.64
Beta-MPP
PEP
Gene name
Name: qcr1
ORFNames: SPBP23A10.15c
From
Schizosaccharomyces pombe (Fission yeast) [TaxID: 4896] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=PR745;
DOI=10.1093/dnares/4.6.363; PubMed=9501991 [NCBI, ExPASy, EBI, Israel, Japan]
Yoshioka S., Kato K., Nakai K., Okayama H., Nojima H.;
"Identification of open reading frames in Schizosaccharomyces pombe cDNAs.";
DNA Res. 4:363-369(1997).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 38366 / 972;
DOI=10.1038/nature724; PubMed=11859360 [NCBI, ExPASy, EBI, Israel, Japan]
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
"The genome sequence of Schizosaccharomyces pombe.";
Nature 415:871-880(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
D89152; BAA13814.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
CU329671; CAB66443.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T42428; T42428.
T50402; T50402.
RefSeq NP_595827.1; -.
3D structure databases
HSSP P10507; 1HR6. [HSSP ENTRY / PDB]
ModBase Q9P7X1.
Protein family/group databases
MEROPS M16.003; -.
Enzyme and pathway databases
BioCyc SPOM-XXX-01:SPOM-XXX-01-003900-MON; -.
Organism-specific databases
GeneDB_Spombe SPBP23A10.15c; -.
Gene expression databases
ArrayExpress Q9P7X1; -.
Ontologies
GO
GO:0005759; Cellular component: mitochondrial matrix (inferred from electronic annotation from UniProtKB-SubCell).
GO:0004222; Molecular function: metalloendopeptidase activity (inferred from electronic annotation from InterPro).
GO:0008270; Molecular function: zinc ion binding (inferred from electronic annotation from InterPro).
GO:0006508; Biological process: proteolysis (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR011237; Pept_M16_core.
IPR011765; Pept_M16_N.
IPR001431; Pept_M16_Zn_BS.
IPR007863; Peptidase_M16_C.
Graphical view of domain structure.
Gene3D G3DSA:3.30.830.10; Pept_M16_core; 2.
Pfam PF00675; Peptidase_M16; 1.
PF05193; Peptidase_M16_C; 1.
Pfam graphical view of domain structure.
PROSITE PS00143; INSULINASE; 1.
ProtoNet Q9P7X1.
Genome annotation databases
GeneID 2541300; -.
KEGG spo:SPBP23A10.15c; -.
NMPDR fig|4896.1.peg.1693; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Hydrolase; Metal-binding; Metalloprotease; Mitochondrion; Protease; Transit peptide; Zinc.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
TRANSIT   1     ?        Mitochondrion (Potential). 
CHAIN   ?   457        Probable mitochondrial-processing peptidase subunit beta. PRO_0000026783
ACT_SITE   69    69        Proton acceptor (By similarity). 
METAL   66    66        Zinc (By similarity). 
METAL   70    70        Zinc (By similarity). 
METAL   146   146        Zinc (By similarity). 
CONFLICT   89    89        E -> G (in Ref. 1; BAA13814). 
CONFLICT   111   112        FK -> PQ (in Ref. 1; BAA13814). 
CONFLICT   117   117        N -> H (in Ref. 1; BAA13814). 
CONFLICT   446   457        NRIRSSISMNRW -> TVFVAVFL (in Ref. 1; BAA13814). 
Sequence information
Length: 457 AA [This is the length of the unprocessed precursor] Molecular weight: 50737 Da [This is the MW of the unprocessed precursor] CRC64: B4978855A8574948 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MLRLQNLPKL VRRFATTALP KTETTTLKNG LTVATEHHPY AQTATVLVGV DAGSRAETAK 

        70         80         90        100        110        120 
NNGAAHFLEH LAFKGTKNRS QKALELEFEN TGAHLNAYTS REQTVYYAHA FKNAVPNAVA 

       130        140        150        160        170        180 
VLADILTNSS ISASAVERER QVILREQEEV DKMADEVVFD HLHATAYQGH PLGRTILGPK 

       190        200        210        220        230        240 
ENIESLTRED LLQYIKDNYR SDRMIISSAG SISHEELVKL AEKYFGHLEP SAEQLSLGAP 

       250        260        270        280        290        300 
RGLKPRFVGS EIRARDDDSP TANIAIAVEG MSWKHPDYFT ALVMQAIIGN WDRAMGASPH 

       310        320        330        340        350        360 
LSSRLSTIVQ QHQLANSFMS FSTSYSDTGL WGIYLVTENL GRIDDLVHFT LQNWARLTVA 

       370        380        390        400        410        420 
TRAEVERAKA QLRASLLLSL DSTTAIAEDI GRQLLTTGRR MSPQEVDLRI GQITEKDVAR 

       430        440        450 
VASEMIWDKD IAVSAVGSIE GLLDYNRIRS SISMNRW 

Q9P7X1 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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