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UniProtKB/Swiss-Prot entry Q9P7D7


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name LCF2_SCHPO
Primary accession number Q9P7D7
Secondary accession numbers None
Integrated into Swiss-Prot on November 13, 2007
Sequence was last modified on October 1, 2000 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 35)
Name and origin of the protein
Protein name Long-chain-fatty-acid--CoA ligase 2
Synonyms EC 6.2.1.3
Long-chain acyl-CoA synthetase 2
Fatty acid activator 2
Gene name
ORFNames: SPBP4H10.11c
From
Schizosaccharomyces pombe (Fission yeast) [TaxID: 4896] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 38366 / 972;
DOI=10.1038/nature724; PubMed=11859360 [NCBI, ExPASy, EBI, Israel, Japan]
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
"The genome sequence of Schizosaccharomyces pombe.";
Nature 415:871-880(2002).
[2]
SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
DOI=10.1038/nbt1222; PubMed=16823372 [NCBI, ExPASy, EBI, Israel, Japan]
Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.;
"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.";
Nat. Biotechnol. 24:841-847(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CU329671; CAB83169.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_596185.1; -.
3D structure databases
HSSP P08659; 1LCI. [HSSP ENTRY / PDB]
ModBase Q9P7D7.
Protein-protein interaction databases
IntAct Q9P7D7; -.
Organism-specific databases
GeneDB_Spombe SPBP4H10.11c; -.
Gene expression databases
ArrayExpress Q9P7D7; -.
Ontologies
GO
GO:0005794; Cellular component: Golgi apparatus (inferred from electronic annotation from UniProtKB-KW).
GO:0005774; Cellular component: vacuolar membrane (inferred from direct assay from GeneDB_SPombe).
GO:0004467; Molecular function: long-chain-fatty-acid-CoA ligase activity (inferred from electronic annotation from EC).
GO:0001676; Biological process: long-chain fatty acid metabolic process (inferred from genetic interaction from GeneDB_SPombe).
QuickGo view.
Family and domain databases
InterPro IPR000873; AMP-dep_Synth/Lig.
Graphical view of domain structure.
Pfam PF00501; AMP-binding; 2.
Pfam graphical view of domain structure.
PRINTS PR00154; AMPBINDING.
PROSITE PS00455; AMP_BINDING; 1.
ProtoNet Q9P7D7.
Genome annotation databases
GeneID 2541350; -.
KEGG spo:SPBP4H10.11c; -.
NMPDR fig|4896.1.peg.2051; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Fatty acid metabolism; Golgi apparatus; Ligase; Lipid metabolism; Membrane; Vacuole.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   689  689     Long-chain-fatty-acid--CoA ligase 2. PRO_0000311761
Sequence information
Length: 689 AA [This is the length of the unprocessed precursor] Molecular weight: 75791 Da [This is the MW of the unprocessed precursor] CRC64: 5F80C06F6EA92F87 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MDIKDYYCVE TKDSKQPGES YIYRSIHSAG KLLDTPEDGV STVYDLLCTA AKNHGEKQAM 

        70         80         90        100        110        120 
GSRKLIKENR EEREIIRKVD NEEVVEKKLW TTYELGPYEY ISFNKVYEIA LALGSGLVAS 

       130        140        150        160        170        180 
GITSETTMLF FAATSAKWFT TAQGCSSQAI PIVTAYETLG EDGIYTSLDE CKSRAIFTDP 

       190        200        210        220        230        240 
NLIPKLLGPL KQSTWVKLIV CSSTPSEDLV ELVKSTAPDV EIITYDNLLS LGKEKPQPPH 

       250        260        270        280        290        300 
PPKADDICCY MYTSGSTGKP KGVVLLHRNI IAALGGINRI LSQHINVKDY VLAYLPLAHI 

       310        320        330        340        350        360 
FEFIFEMCCL YWGGVLGYAS PRTLTDASVV NCKGDLTEFR PTVLIGVPAV YELIKKGILA 

       370        380        390        400        410        420 
KVSSMPAHRQ KVFSGSLSLK QYLIERNLPG SAALDAIVFN KVKAATGGRL RYCISGGAAL 

       430        440        450        460        470        480 
AASTQAFLSS CICPVLPGYG LTETCAGSFV LSPEQWHLYA NTVGFPIPSI EFKLVDIPDL 

       490        500        510        520        530        540 
GYYTDSSPPR GEVWIRGPAV CNGYLNRPED NKAAFTEDGW FKTGDVGEIA KGNTLRLIDR 

       550        560        570        580        590        600 
KKNIVKSLNG EYIALEKIEA QFFTSPLVSN VCAYADVNHA KPVVIVNPDE NGLRTYLTKN 

       610        620        630        640        650        660 
SGSSFNGNPN DTLTNLCKDS GVQHLILKEL INIGKQQRLA SIEIPEGVVL SDFEWTAENN 

       670        680 
FLTASRKVKR QVIVAHYSDE IQKAYSKKH 

Q9P7D7 in FASTA format

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