[1]
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NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND INDUCTION.
TISSUE=Thyroid;
DOI=10.1074/jbc.M000916200; PubMed=10806195 [NCBI, ExPASy, EBI, Israel, Japan]
De Deken X.,
Wang D.,
Many M.-C.,
Costagliola S.,
Libert F.,
Vassart G.,
Dumont J.E.,
Miot F.;
"Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family.";
J. Biol. Chem. 275:23227-23233(2000).
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[2]
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NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT PHE-1178, FUNCTION, CATALYTIC ACTIVITY, ENZYME REGULATION, DEVELOPMENTAL STAGE, AND TISSUE SPECIFICITY.
TISSUE=Lung;
DOI=10.1083/jcb.200103132; PubMed=11514595 [NCBI, ExPASy, EBI, Israel, Japan]
Edens W.A.,
Sharling L.,
Cheng G.,
Shapira R.,
Kinkade J.M.,
Lee T.,
Edens H.A.,
Tang X.,
Sullards C.,
Flaherty D.B.,
Benian G.M.,
Lambeth J.D.;
"Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phox.";
J. Cell Biol. 154:879-891(2001).
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[3]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1030-1551 (ISOFORMS 1/2), AND VARIANT ARG-1026.
TISSUE=Lung, and Trachea;
DOI=10.1038/ng1285; PubMed=14702039 [NCBI, ExPASy, EBI, Israel, Japan]
Ota T.,
Suzuki Y.,
Nishikawa T.,
Otsuki T.,
Sugiyama T.,
Irie R.,
Wakamatsu A.,
Hayashi K.,
Sato H.,
Nagai K.,
Kimura K.,
Makita H.,
Sekine M.,
Obayashi M.,
Nishi T.,
Shibahara T.,
Tanaka T.,
Ishii S.,
Yamamoto J., ![]()
Saito K.,
Kawai Y.,
Isono Y.,
Nakamura Y.,
Nagahari K.,
Murakami K.,
Yasuda T.,
Iwayanagi T.,
Wagatsuma M.,
Shiratori A.,
Sudo H.,
Hosoiri T.,
Kaku Y.,
Kodaira H.,
Kondo H.,
Sugawara M.,
Takahashi M.,
Kanda K.,
Yokoi T.,
Furuya T.,
Kikkawa E.,
Omura Y.,
Abe K.,
Kamihara K.,
Katsuta N.,
Sato K.,
Tanikawa M.,
Yamazaki M.,
Ninomiya K.,
Ishibashi T.,
Yamashita H.,
Murakawa K.,
Fujimori K.,
Tanai H.,
Kimata M.,
Watanabe M.,
Hiraoka S.,
Chiba Y.,
Ishida S.,
Ono Y.,
Takiguchi S.,
Watanabe S.,
Yosida M.,
Hotuta T.,
Kusano J.,
Kanehori K.,
Takahashi-Fujii A.,
Hara H.,
Tanase T.-O.,
Nomura Y.,
Togiya S.,
Komai F.,
Hara R.,
Takeuchi K.,
Arita M.,
Imose N.,
Musashino K.,
Yuuki H.,
Oshima A.,
Sasaki N.,
Aotsuka S.,
Yoshikawa Y.,
Matsunawa H.,
Ichihara T.,
Shiohata N.,
Sano S.,
Moriya S.,
Momiyama H.,
Satoh N.,
Takami S.,
Terashima Y.,
Suzuki O.,
Nakagawa S.,
Senoh A.,
Mizoguchi H.,
Goto Y.,
Shimizu F.,
Wakebe H.,
Hishigaki H.,
Watanabe T.,
Sugiyama A.,
Takemoto M.,
Kawakami B.,
Yamazaki M.,
Watanabe K.,
Kumagai A.,
Itakura S.,
Fukuzumi Y.,
Fujimori Y.,
Komiyama M.,
Tashiro H.,
Tanigami A.,
Fujiwara T.,
Ono T.,
Yamada K.,
Fujii Y.,
Ozaki K.,
Hirao M.,
Ohmori Y.,
Kawabata A.,
Hikiji T.,
Kobatake N.,
Inagaki H.,
Ikema Y.,
Okamoto S.,
Okitani R.,
Kawakami T.,
Noguchi S.,
Itoh T.,
Shigeta K.,
Senba T.,
Matsumura K.,
Nakajima Y.,
Mizuno T.,
Morinaga M.,
Sasaki M.,
Togashi T.,
Oyama M.,
Hata H.,
Watanabe M.,
Komatsu T.,
Mizushima-Sugano J.,
Satoh T.,
Shirai Y.,
Takahashi Y.,
Nakagawa K.,
Okumura K.,
Nagase T.,
Nomura N.,
Kikuchi H.,
Masuho Y.,
Yamashita R.,
Nakai K.,
Yada T.,
Nakamura Y.,
Ohara O.,
Isogai T.,
Sugano S.;
"Complete sequencing and characterization of 21,243 full-length human cDNAs.";
Nat. Genet. 36:40-45(2004).
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[4]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nature04601; PubMed=16572171 [NCBI, ExPASy, EBI, Israel, Japan]
Zody M.C.,
Garber M.,
Sharpe T.,
Young S.K.,
Rowen L.,
O'Neill K.,
Whittaker C.A.,
Kamal M.,
Chang J.L.,
Cuomo C.A.,
Dewar K.,
FitzGerald M.G.,
Kodira C.D.,
Madan A.,
Qin S.,
Yang X.,
Abbasi N.,
Abouelleil A.,
Arachchi H.M., ![]()
Baradarani L.,
Birditt B.,
Bloom S.,
Bloom T.,
Borowsky M.L.,
Burke J.,
Butler J.,
Cook A.,
DeArellano K.,
DeCaprio D.,
Dorris L. III,
Dors M.,
Eichler E.E.,
Engels R.,
Fahey J.,
Fleetwood P.,
Friedman C.,
Gearin G.,
Hall J.L.,
Hensley G.,
Johnson E.,
Jones C.,
Kamat A.,
Kaur A.,
Locke D.P.,
Madan A.,
Munson G.,
Jaffe D.B.,
Lui A.,
Macdonald P.,
Mauceli E.,
Naylor J.W.,
Nesbitt R.,
Nicol R.,
O'Leary S.B.,
Ratcliffe A.,
Rounsley S.,
She X.,
Sneddon K.M.B.,
Stewart S.,
Sougnez C.,
Stone S.M.,
Topham K.,
Vincent D.,
Wang S.,
Zimmer A.R.,
Birren B.W.,
Hood L.,
Lander E.S.,
Nusbaum C.;
"Analysis of the DNA sequence and duplication history of human chromosome 15.";
Nature 440:671-675(2006).
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[5]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[6]
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GLYCOSYLATION.
DOI=10.1006/excr.2001.5444; PubMed=11822874 [NCBI, ExPASy, EBI, Israel, Japan]
De Deken X.,
Wang D.,
Dumont J.E.,
Miot F.;
"Characterization of ThOX proteins as components of the thyroid H(2)O(2)-generating system.";
Exp. Cell Res. 273:187-196(2002).
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[7]
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FUNCTION, AND TISSUE SPECIFICITY.
DOI=10.1096/fj.02-1104fje; PubMed=12824283 [NCBI, ExPASy, EBI, Israel, Japan]
Geiszt M.,
Witta J.,
Baffi J.,
Lekstrom K.,
Leto T.L.;
"Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense.";
FASEB J. 17:1502-1504(2003).
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[8]
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SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
DOI=10.1074/jbc.M404983200; PubMed=15210697 [NCBI, ExPASy, EBI, Israel, Japan]
Schwarzer C.,
Machen T.E.,
Illek B.,
Fischer H.;
"NADPH oxidase-dependent acid production in airway epithelial cells.";
J. Biol. Chem. 279:36454-36461(2004).
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[9]
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INDUCTION.
DOI=10.1016/j.febslet.2005.08.002; PubMed=16111680 [NCBI, ExPASy, EBI, Israel, Japan]
Harper R.W.,
Xu C.,
Eiserich J.P.,
Chen Y.,
Kao C.-Y.,
Thai P.,
Setiadi H.,
Wu R.;
"Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium.";
FEBS Lett. 579:4911-4917(2005).
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[10]
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INTERACTION WITH TXNDC11; TPO AND CYBA.
DOI=10.1074/jbc.M407709200; PubMed=15561711 [NCBI, ExPASy, EBI, Israel, Japan]
Wang D.,
De Deken X.,
Milenkovic M.,
Song Y.,
Pirson I.,
Dumont J.E.,
Miot F.;
"Identification of a novel partner of duox: EFP1, a thioredoxin-related protein.";
J. Biol. Chem. 280:3096-3103(2005).
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[11]
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CATALYTIC ACTIVITY, AND ENZYME REGULATION.
DOI=10.1074/jbc.M500516200; PubMed=15972824 [NCBI, ExPASy, EBI, Israel, Japan]
Ameziane-El-Hassani R.,
Morand S.,
Boucher J.L.,
Frapart Y.-M.,
Apostolou D.,
Agnandji D.,
Gnidehou S.,
Ohayon R.,
Noel-Hudson M.-S.,
Francon J.,
Lalaoui K.,
Virion A.,
Dupuy C.;
"Dual oxidase-2 has an intrinsic Ca2+-dependent H2O2-generating activity.";
J. Biol. Chem. 280:30046-30054(2005).
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