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UniProtKB/Swiss-Prot entry Q9N4Z0

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name L2HDH_CAEEL
Primary accession number Q9N4Z0
Secondary accession numbers None
Integrated into Swiss-Prot on April 29, 2008
Sequence was last modified on October 1, 2001 (Sequence version 2)
Annotations were last modified on    November 4, 2008 (Entry version 36)
Name and origin of the protein
Protein name L-2-hydroxyglutarate dehydrogenase, mitochondrial [Precursor]
Synonym EC 1.1.99.2
Gene name
ORFNames: Y45G12B.3
From
Caenorhabditis elegans [TaxID: 6239] 
Taxonomy Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Bristol N2;
DOI=10.1126/science.282.5396.2012; PubMed=9851916 [NCBI, ExPASy, EBI, Israel, Japan]
The C. elegans sequencing consortium;
"Genome sequence of the nematode C. elegans: a platform for investigating biology.";
Science 282:2012-2018(1998).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AC006768; AAF60576.2; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_503730.1; -.
UniGene Cel.1737
3D structure databases
ModBase Q9N4Z0.
Organism-specific databases
WormBase WBGene00021564; Y45G12B.3.
WormPep Y45G12B.3; CE28366. [WormPep / WorfDB]
Gene expression databases
ArrayExpress Q9N4Z0; -.
Ontologies
GO
GO:0005739; Cellular component: mitochondrion (inferred from electronic annotation from UniProtKB-KW).
GO:0047545; Molecular function: 2-hydroxyglutarate dehydrogenase activity (inferred from electronic annotation from EC).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR006076; FAD-dep_OxRdtase.
Graphical view of domain structure.
Pfam PF01266; DAO; 1.
Pfam graphical view of domain structure.
ProtoNet Q9N4Z0.
Genome annotation databases
Ensembl Y45G12B.3; Caenorhabditis elegans. [Contig view]
GeneID 178733; -.
KEGG cel:Y45G12B.3; -.
Other
NextBio 902318; -.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; FAD; Flavoprotein; Mitochondrion; Oxidoreductase; Transit peptide.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
TRANSIT   1     ?        Mitochondrion (Potential). 
CHAIN   ?   433        L-2-hydroxyglutarate dehydrogenase, mitochondrial. PRO_0000331211
Sequence information
Length: 433 AA [This is the length of the unprocessed precursor] Molecular weight: 47901 Da [This is the MW of the unprocessed precursor] CRC64: 2565A7A72A5582BA [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MLNRGTFQVF RGISGPPKKS VDLPKYDLVI VGGGIVGCAT ARQLLIEKPQ LKVALIEKEK 

        70         80         90        100        110        120 
ELAVHQSGHN SGVIHAGIYY TPGSLKAKLC VEGLDLSYEF FDKEKVPYKK TGKLIVAVEP 

       130        140        150        160        170        180 
EEVPRLDALF SRAQTNGCRD IEMIDSSKIT ELEPHCRGLK ALWSPHTGIV DWGYVTKRFG 

       190        200        210        220        230        240 
EDFEKRGGKI YTSYPLEKIS DNHDPGYPIR VSSGPALAEF ETKNLITCAG LQSDRVAALS 

       250        260        270        280        290        300 
GCSTDPKIVP FRGEYLLLKP EKRHLVKTNI YPVPDPRFPF LGVHFTPRMN GDIWLGPNAV 

       310        320        330        340        350        360 
LAYKREGYSY FSISPSDLLE SLSYSGMQKL VKKHFTFGIK ELYRGVWIAA QVKQLQRFIP 

       370        380        390        400        410        420 
ELKLSDVTRG PAGVRAQAMD SAGNLVDDFV FDSGTGKLSP LLMHVRNAPS PAATSSLAIA 

       430 
KMITSEAINR FKL
Q9N4Z0 in FASTA format

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