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UniProtKB/Swiss-Prot entry Q9LW29


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AFB2_ARATH
Primary accession number Q9LW29
Secondary accession numbers None
Integrated into Swiss-Prot on January 23, 2007
Sequence was last modified on October 1, 2000 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 40)
Name and origin of the protein
Protein name Protein AUXIN SIGNALING F-BOX 2
Synonyms None
Gene name
Name: AFB2
Synonyms: LRF2
OrderedLocusNames: At3g26810
ORFNames: MDJ14.12
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1093/dnares/7.2.131; PubMed=10819329 [NCBI, ExPASy, EBI, Israel, Japan]
Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
"Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence features of the regions of 4,504,864 bp covered by sixty P1 and TAC clones.";
DNA Res. 7:131-135(2000).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
[3]
LEUCINE-RICH REPEATS.
DOI=10.1023/A:1014440531842; PubMed=12008900 [NCBI, ExPASy, EBI, Israel, Japan]
Thelander M., Fredriksson D., Schouten J., Hoge J.H.C., Ronne H.;
"Cloning by pathway activation in yeast: identification of an Arabidopsis thaliana F-box protein that can turn on glucose repression.";
Plant Mol. Biol. 49:69-79(2002).
[4]
FUNCTION, TISSUE SPECIFICITY, SUBCELLULAR LOCATION, AND INTERACTION WITH IAA7.
DOI=10.1016/j.devcel.2005.05.014; PubMed=15992545 [NCBI, ExPASy, EBI, Israel, Japan]
Dharmasiri N., Dharmasiri S., Weijers D., Lechner E., Yamada M., Hobbie L., Ehrismann J.S., Juergens G., Estelle M.;
"Plant development is regulated by a family of auxin receptor F box proteins.";
Dev. Cell 9:109-119(2005).
[5]
FUNCTION.
DOI=10.1038/nature03543; PubMed=15917797 [NCBI, ExPASy, EBI, Israel, Japan]
Dharmasiri N., Dharmasiri S., Estelle M.;
"The F-box protein TIR1 is an auxin receptor.";
Nature 435:441-445(2005).
[6]
FUNCTION, AND INDUCTION.
DOI=10.1126/science.1126088; PubMed=16627744 [NCBI, ExPASy, EBI, Israel, Japan]
Navarro L., Dunoyer P., Jay F., Arnold B., Dharmasiri N., Estelle M., Voinnet O., Jones J.D.G.;
"A plant miRNA contributes to antibacterial resistance by repressing auxin signaling.";
Science 312:436-439(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AB016889; BAB01228.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY062568; AAL32646.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BT010396; AAQ56839.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_566800.1; -.
UniGene At.6031
3D structure databases
ModBase Q9LW29.
Protein-protein interaction databases
IntAct Q9LW29; -.
Organism-specific databases
TAIR At3g26810; -.
Ontologies
GO
GO:0010011; Molecular function: auxin binding (inferred from genetic interaction from TAIR).
GO:0005515; Molecular function: protein binding (inferred from physical interaction from IntAct).
GO:0002237; Biological process: response to molecule of bacterial origin (inferred from expression pattern from TAIR).
QuickGo view.
Family and domain databases
InterPro IPR001810; F-box.
Graphical view of domain structure.
SMART SM00256; FBOX; 1.
SMART graphical view of domain structure.
PROSITE PS50181; FBOX; FALSE_NEG.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q9LW29.
Genome annotation databases
GeneID 822296; -.
GenomeReviews BA000014_GR; AT3G26810.
KEGG ath:AT3G26810; -.
NMPDR fig|3702.1.peg.14963; -.
Other
ProtoNet Q9LW29.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Auxin signaling pathway; Complete proteome; Developmental protein; Leucine-rich repeat; Nucleus; Plant defense; Repeat.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   575  575     Protein AUXIN SIGNALING F-BOX 2. PRO_0000272243
DOMAIN   1    47  47     F-box. 
REPEAT   91   108  18     LRR 1. 
REPEAT   109   141  33     LRR 2. 
REPEAT   142   169  28     LRR 3. 
REPEAT   170   196  27     LRR 4. 
REPEAT   197   223  27     LRR 5. 
REPEAT   224   250  27     LRR 6. 
REPEAT   251   274  24     LRR 7. 
REPEAT   275   300  26     LRR 8. 
REPEAT   301   324  24     LRR 9. 
REPEAT   325   357  33     LRR 10. 
REPEAT   358   382  25     LRR 11. 
REPEAT   383   417  35     LRR 12. 
REPEAT   418   444  27     LRR 13. 
REPEAT   445   466  22     LRR 14. 
REPEAT   467   488  22     LRR 15. 
REPEAT   489   512  24     LRR 16. 
Sequence information
Length: 575 AA [This is the length of the unprocessed precursor] Molecular weight: 64605 Da [This is the MW of the unprocessed precursor] CRC64: D383C4E0A76D50D6 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MNYFPDEVIE HVFDFVTSHK DRNAISLVCK SWYKIERYSR QKVFIGNCYA INPERLLRRF 

        70         80         90        100        110        120 
PCLKSLTLKG KPHFADFNLV PHEWGGFVLP WIEALARSRV GLEELRLKRM VVTDESLELL 

       130        140        150        160        170        180 
SRSFVNFKSL VLVSCEGFTT DGLASIAANC RHLRDLDLQE NEIDDHRGQW LSCFPDTCTT 

       190        200        210        220        230        240 
LVTLNFACLE GETNLVALER LVARSPNLKS LKLNRAVPLD ALARLMACAP QIVDLGVGSY 

       250        260        270        280        290        300 
ENDPDSESYL KLMAVIKKCT SLRSLSGFLE AAPHCLSAFH PICHNLTSLN LSYAAEIHGS 

       310        320        330        340        350        360 
HLIKLIQHCK KLQRLWILDS IGDKGLEVVA STCKELQELR VFPSDLLGGG NTAVTEEGLV 

       370        380        390        400        410        420 
AISAGCPKLH SILYFCQQMT NAALVTVAKN CPNFIRFRLC ILEPNKPDHV TSQPLDEGFG 

       430        440        450        460        470        480 
AIVKACKSLR RLSLSGLLTD QVFLYIGMYA NQLEMLSIAF AGDTDKGMLY VLNGCKKMKK 

       490        500        510        520        530        540 
LEIRDSPFGD TALLADVSKY ETMRSLWMSS CEVTLSGCKR LAEKAPWLNV EIINENDNNR 

       550        560        570 
MEENGHEGRQ KVDKLYLYRT VVGTRMDAPP FVWIL 

Q9LW29 in FASTA format

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