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UniProtKB/Swiss-Prot entry Q9LPW7


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AFB3_ARATH
Primary accession number Q9LPW7
Secondary accession numbers None
Integrated into Swiss-Prot on January 23, 2007
Sequence was last modified on October 1, 2000 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 49)
Name and origin of the protein
Protein name Protein AUXIN SIGNALING F-BOX 3
Synonyms None
Gene name
Name: AFB3
OrderedLocusNames: At1g12820
ORFNames: F13K23.7
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/35048500; PubMed=11130712 [NCBI, ExPASy, EBI, Israel, Japan]
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.;
"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
Nature 408:816-820(2000).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K., Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.;
"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
[4]
FUNCTION, TISSUE SPECIFICITY, SUBCELLULAR LOCATION, AND INTERACTION WITH CUL1; IAA7; IAA12 AND SKP1A/ASK1.
DOI=10.1016/j.devcel.2005.05.014; PubMed=15992545 [NCBI, ExPASy, EBI, Israel, Japan]
Dharmasiri N., Dharmasiri S., Weijers D., Lechner E., Yamada M., Hobbie L., Ehrismann J.S., Juergens G., Estelle M.;
"Plant development is regulated by a family of auxin receptor F box proteins.";
Dev. Cell 9:109-119(2005).
[5]
FUNCTION.
DOI=10.1038/nature03543; PubMed=15917797 [NCBI, ExPASy, EBI, Israel, Japan]
Dharmasiri N., Dharmasiri S., Estelle M.;
"The F-box protein TIR1 is an auxin receptor.";
Nature 435:441-445(2005).
[6]
INDUCTION.
DOI=10.1126/science.1126088; PubMed=16627744 [NCBI, ExPASy, EBI, Israel, Japan]
Navarro L., Dunoyer P., Jay F., Arnold B., Dharmasiri N., Estelle M., Voinnet O., Jones J.D.G.;
"A plant miRNA contributes to antibacterial resistance by repressing auxin signaling.";
Science 312:436-439(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE005172; AAF78487.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY099541; AAM20393.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BT002118; AAN72129.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AK227280; BAE99304.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR F86261; F86261.
RefSeq NP_563915.1; -.
UniGene At.71229
3D structure databases
ModBase Q9LPW7.
Protein-protein interaction databases
IntAct Q9LPW7; -.
Organism-specific databases
TAIR At1g12820; -.
Gene expression databases
ArrayExpress Q9LPW7; -.
Ontologies
GO
GO:0010011; Molecular function: auxin binding (inferred from genetic interaction from TAIR).
GO:0005515; Molecular function: protein binding (inferred from physical interaction from IntAct).
GO:0002237; Biological process: response to molecule of bacterial origin (inferred from expression pattern from TAIR).
QuickGo view.
Family and domain databases
InterPro IPR001810; F-box.
Graphical view of domain structure.
SMART SM00256; FBOX; 1.
SMART graphical view of domain structure.
PROSITE PS50181; FBOX; FALSE_NEG.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q9LPW7.
Genome annotation databases
GeneID 837838; -.
GenomeReviews CT485782_GR; AT1G12820.
KEGG ath:AT1G12820; -.
NMPDR fig|3702.1.peg.1550; -.
Other
ProtoNet Q9LPW7.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Auxin signaling pathway; Complete proteome; Developmental protein; Leucine-rich repeat; Nucleus; Plant defense; Repeat; Ubl conjugation pathway.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   577  577     Protein AUXIN SIGNALING F-BOX 3. PRO_0000272244
DOMAIN   1    45  45     F-box. 
REPEAT   91   108  18     LRR 1. 
REPEAT   109   141  33     LRR 2. 
REPEAT   142   169  28     LRR 3. 
REPEAT   170   196  27     LRR 4. 
REPEAT   197   223  27     LRR 5. 
REPEAT   224   250  27     LRR 6. 
REPEAT   251   274  24     LRR 7. 
REPEAT   275   300  26     LRR 8. 
REPEAT   301   324  24     LRR 9. 
REPEAT   325   359  35     LRR 10. 
REPEAT   360   384  25     LRR 11. 
REPEAT   385   419  35     LRR 12. 
REPEAT   420   446  27     LRR 13. 
REPEAT   447   468  22     LRR 14. 
REPEAT   469   490  22     LRR 15. 
REPEAT   491   514  24     LRR 16. 
Sequence information
Length: 577 AA [This is the length of the unprocessed precursor] Molecular weight: 64906 Da [This is the MW of the unprocessed precursor] CRC64: 8E419B4D83068661 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MNYFPDEVIE HVFDFVASHK DRNSISLVCK SWHKIERFSR KEVFIGNCYA INPERLIRRF 

        70         80         90        100        110        120 
PCLKSLTLKG KPHFADFNLV PHEWGGFVHP WIEALARSRV GLEELRLKRM VVTDESLDLL 

       130        140        150        160        170        180 
SRSFANFKSL VLVSCEGFTT DGLASIAANC RHLRELDLQE NEIDDHRGQW LNCFPDSCTT 

       190        200        210        220        230        240 
LMSLNFACLK GETNVAALER LVARSPNLKS LKLNRAVPLD ALARLMSCAP QLVDLGVGSY 

       250        260        270        280        290        300 
ENEPDPESFA KLMTAIKKYT SLRSLSGFLE VAPLCLPAFY PICQNLISLN LSYAAEIQGN 

       310        320        330        340        350        360 
HLIKLIQLCK RLQRLWILDS IGDKGLAVVA ATCKELQELR VFPSDVHGEE DNNASVTEVG 

       370        380        390        400        410        420 
LVAISAGCPK LHSILYFCKQ MTNAALIAVA KNCPNFIRFR LCILEPHKPD HITFQSLDEG 

       430        440        450        460        470        480 
FGAIVQACKG LRRLSVSGLL TDQVFLYIGM YAEQLEMLSI AFAGDTDKGM LYVLNGCKKM 

       490        500        510        520        530        540 
RKLEIRDSPF GNAALLADVG RYETMRSLWM SSCEVTLGGC KRLAQNSPRL NVEIINENEN 

       550        560        570 
NGMEQNEEDE REKVDKLYLY RTVVGTRKDA PPYVRIL 

Q9LPW7 in FASTA format

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