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UniProtKB/Swiss-Prot entry Q9JH69

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NS1AB_TASV1
Primary accession number Q9JH69
Secondary accession numbers None
Integrated into Swiss-Prot on April 8, 2008
Sequence was last modified on April 8, 2008 (Sequence version 3)
Annotations were last modified on    July 22, 2008 (Entry version 32)
Name and origin of the protein
Protein name Non-structural polyprotein 1AB
Synonyms None
Contains Protein p19
Transmembrane protein 1A
Serine protease p27
     (p27)
     (EC 3.4.21.-)
Protein p20
RNA-directed RNA polymerase p57
     (p57)
     (EC 2.7.7.48)
Gene name
Name: ORF1
From
Turkey astrovirus 1 (TAstV-1) [TaxID: 364370] 
Taxonomy Viruses; ssRNA positive-strand viruses, no DNA stage; Astroviridae; Avastrovirus.
Virus host Meleagris gallopavo (Common turkey) [TaxID: 9103]
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC RNA].
DOI=10.1016/S0168-1702(02)00269-1; PubMed=12573498 [NCBI, ExPASy, EBI, Israel, Japan]
Jonassen C.M., Jonassen T.O., Sveen T.M., Grinde B.;
"Complete genomic sequences of astroviruses from sheep and turkey: comparison with related viruses.";
Virus Res. 91:195-201(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
Y15936; CAB95006.3; ALT_SEQ; Genomic_RNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
ModBase Q9JH69.
Family and domain databases
InterPro IPR001205; RNA_pol_P3D.
IPR007094; RNA_pol_PSvir.
Graphical view of domain structure.
Pfam PF00680; RdRP_1; 1.
Pfam graphical view of domain structure.
PROSITE PS50507; RDRP_SSRNA_POS; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q9JH69.
Other
ProtoNet Q9JH69.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Coiled coil; Hydrolase; Membrane; Nucleotide-binding; Nucleotidyltransferase; Protease; Ribosomal frameshifting; RNA replication; RNA-directed RNA polymerase; Thiol protease; Transferase; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom    To Length Description FTId
CHAIN   1   1611  1611     Non-structural polyprotein 1AB. PRO_0000327307
CHAIN   1    168  168     Protein p19 (Potential). PRO_0000327308
CHAIN   169    508  340     Transmembrane protein 1A (Potential). PRO_0000327309
CHAIN   509    795  287     Serine protease p27 (Potential). PRO_0000327310
CHAIN   796   1027  232     Protein p20 (Potential). PRO_0000327311
CHAIN   1028   1611  584     RNA-directed RNA polymerase p57 (Potential). PRO_0000327312
TRANSMEM   195    215  21     Potential. 
TRANSMEM   329    348  20     Potential. 
TRANSMEM   353    373  21     Potential. 
TRANSMEM   375    395  21     Potential. 
TRANSMEM   397    417  21     Potential. 
TRANSMEM   426    446  21     Potential. 
TRANSMEM   450    470  21     Potential. 
DOMAIN   1352   1486  135     RdRp catalytic. 
COILED   124    187  64     Potential. 
ACT_SITE   550    550        Charge relay system; for serine protease activity (By similarity). 
ACT_SITE   582    582        Charge relay system; for serine protease activity (By similarity). 
ACT_SITE   647    647        Charge relay system; for serine protease activity (By similarity). 
SITE   168    169  2     Cleavage (Potential). 
SITE   508    509  2     Cleavage (Potential). 
SITE   795    796  2     Cleavage (Potential). 
SITE   1027   1028  2     Cleavage (Potential). 
Sequence information
Length: 1611 AA [This is the length of the unprocessed precursor] Molecular weight: 183203 Da [This is the MW of the unprocessed precursor] CRC64: F3827B808E34A58F [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAAAAASALG ASAPKALAPA DGPIVAGLDK LVNLEGVHDL FEAMRGAYGE DPAWKGLMSC 

        70         80         90        100        110        120 
DVVYLKDITT AIGVKDTSVG IFRKFSDGCS WCPTGAECFL SMKDLAYMKA QSAKAQRLTA 

       130        140        150        160        170        180 
SLATTSNLIA RAMRAESELK RARDEERKVD ARYKDILEHS LAARKALQKE LDETRERELH 

       190        200        210        220        230        240 
LLKELGKRSS IRTKAFSFFD WLFMAVVFFL FLHYTSAECV KPDFGCLVVN SNLPVPSLTF 

       250        260        270        280        290        300 
HDVMARCYNT FGNIVLSSQI DAARLREECE QSANKFLGTH IGDPAHKVWC ENRLETLIPV 

       310        320        330        340        350        360 
ECDSSEFLEI FTSNLNAFMV SVSQFYKTIS YYKLDALVTF AFSAALATNK LKMVMVLPLL 

       370        380        390        400        410        420 
LVALYLNVPP ITVTIASVIF QPLILPFVGF QLVFPNFLPY NLFVAWVWMV CQAFFSSDGV 

       430        440        450        460        470        480 
KLLVSVSTAL VQVVFLAVWS ISVIVLQQLS IPMVAQILLF VATLTVSVGV KFANSTITVV 

       490        500        510        520        530        540 
HPDGNTEKVS RVTLVRQSMA KRISQIKQSL TIRGVIPSGP NRFDSIVVVE GQGGSGVGWR 

       550        560        570        580        590        600 
FMNSIFTAGH VVQGSKFVTI KSESTQVKVK VKRVIDLFEC VDTLVEIPLT KEFQHIKPLR 

       610        620        630        640        650        660 
LAKKVEDSYL QLCAFKPDMV EKASYQGWCT IDSGFIFNSF NTQFGNSGAP YVDSDGRLVG 

       670        680        690        700        710        720 
MHLGSQGVIS QGVVLVDTLK TQFLAQQSQI DDQLMERIIE GTKVSHAAIL TELDRMRTKV 

       730        740        750        760        770        780 
EEVALVSARV NQLESQLKDL YEFSSNSIKC LSDDIEKMVC AQLFDEINLQ SVMEKISALP 

       790        800        810        820        830        840 
PTEKLAKLVE VFVEQKKKGK TKRTARGGKH ALGKKYLSKA HFSRMRMLTE EEYNKMVEDG 

       850        860        870        880        890        900 
FSPDEIKEVV DQLREQAWQN YLIDNDIGED DDLDWYDDML EDERLNEEID RRVEAALEDR 

       910        920        930        940        950        960 
GELAYQKIRR TFVDQALIHL ITLKKGNWQT TKVECQPERE EAYKEQFQKA VKQEDLTEGT 

       970        980        990       1000       1010       1020 
SYAIYSAGDA TILIENKEID HTEIKPVTTG AKTVQEYPKD ARTTVATFDD NKKDIVKTKR 

      1030       1040       1050       1060       1070       1080 
TTEIVLEQRK KTCRTCGETR PHNHKMCRDR HTRRFCFWCG VVHSDVEGHS RDLKCPKCSA 

      1090       1100       1110       1120       1130       1140 
GFANLREMEQ HAVTTCSKKL DSHPEPSRVF QPLDFGLGIF DWRFDLQPIR HHVAVPMNVE 

      1150       1160       1170       1180       1190       1200 
VLGYIPVDRL VERRNVITDP LLKLVEPWRQ ETYGPAVWTI KAYNKMFEKF FYSEPLEFAQ 

      1210       1220       1230       1240       1250       1260 
LDSSILNLAD SYCLQEHDYM SGSQIVPITS TEKNLDSTPG YPKFKVFSTE REYLSTCGWD 

      1270       1280       1290       1300       1310       1320 
EYKTVWQVGP REKPLWWCFL KTEVLKLAKI EQDDIRMILC TDPVFTRIGA AFEQHQNSLM 

      1330       1340       1350       1360       1370       1380 
KLETENHHAQ VGWSPFFGGI HRRATRLYGE HRYYVELDWT RFDGTIPPEL FRRIKLMRFF 

      1390       1400       1410       1420       1430       1440 
LLDPKYKTPE NRDRYNWYVE NLIDKVVLLP TGEVCKIYGG NPSGQFSTTV DNNFVNVWLT 

      1450       1460       1470       1480       1490       1500 
VFELAYLFYK EHNRLPTICE IKKHTDWICY GDDRLLAVDK RFINSYDTAA VIAMYKDVFG 

      1510       1520       1530       1540       1550       1560 
MWVKPDNIKV FPSLEGVSFC GMVWTKRKGQ YVGKPNVDKI LSTLSDPVSR LPDIQSLWGK 

      1570       1580       1590       1600       1610 
LVSLRLLCEN ESDEVVDYLD KQIESVSRHA KEAGIALPKI GPDFYAEIWI D
Q9JH69 in FASTA format

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