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UniProtKB/Swiss-Prot entry Q9ILI5

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NS1AB_TASV2
Primary accession number Q9ILI5
Secondary accession numbers None
Integrated into Swiss-Prot on April 8, 2008
Sequence was last modified on April 8, 2008 (Sequence version 2)
Annotations were last modified on    July 22, 2008 (Entry version 32)
Name and origin of the protein
Protein name Non-structural polyprotein 1AB
Synonyms None
Contains Protein p19
Transmembrane protein 1A
Serine protease p27
     (p27)
     (EC 3.4.21.-)
Protein p20
RNA-directed RNA polymerase p57
     (p57)
     (EC 2.7.7.48)
Gene name
Name: ORF1
From
Turkey astrovirus 2 (TAstV-2) [TaxID: 246343] 
Taxonomy Viruses; ssRNA positive-strand viruses, no DNA stage; Astroviridae; Avastrovirus.
Virus host Meleagris gallopavo (Common turkey) [TaxID: 9103]
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC RNA].
DOI=10.1128/JVI.74.13.6173-6177.2000; PubMed=10846102 [NCBI, ExPASy, EBI, Israel, Japan]
Koci M.D., Seal B.S., Schultz-Cherry S.;
"Molecular characterization of an avian astrovirus.";
J. Virol. 74:6173-6177(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF206663; AAF60952.1; ALT_SEQ; Genomic_RNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_987087.1; -.
3D structure databases
ModBase Q9ILI5.
Family and domain databases
InterPro IPR001850; Peptidase_S7.
IPR001205; RNA_pol_P3D.
IPR007094; RNA_pol_PSvir.
Graphical view of domain structure.
Pfam PF00949; Peptidase_S7; 1.
PF00680; RdRP_1; 1.
Pfam graphical view of domain structure.
PROSITE PS50507; RDRP_SSRNA_POS; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q9ILI5.
Genome annotation databases
GeneID 2943319; -.
Other
ProtoNet Q9ILI5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Coiled coil; Hydrolase; Membrane; Nucleotide-binding; Nucleotidyltransferase; Protease; Ribosomal frameshifting; RNA replication; RNA-directed RNA polymerase; Thiol protease; Transferase; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom    To Length Description FTId
CHAIN   1   1638  1638     Non-structural polyprotein 1AB. PRO_0000327313
CHAIN   1    170  170     Protein p19 (Potential). PRO_0000327314
CHAIN   171    552  382     Transmembrane protein 1A (Potential). PRO_0000327315
CHAIN   553    797  245     Serine protease p27 (Potential). PRO_0000327316
CHAIN   798   1051  254     Protein p20 (Potential). PRO_0000327317
CHAIN   1052   1638  587     RNA-directed RNA polymerase p57 (Potential). PRO_0000327318
TRANSMEM   220    240  21     Potential. 
TRANSMEM   379    398  20     Potential. 
TRANSMEM   407    427  21     Potential. 
TRANSMEM   437    457  21     Potential. 
TRANSMEM   479    499  21     Potential. 
TRANSMEM   507    527  21     Potential. 
DOMAIN   1381   1515  135     RdRp catalytic. 
COILED   130    222  93     Potential. 
COILED   758    788  31     Potential. 
ACT_SITE   600    600        Charge relay system; for serine protease activity (By similarity). 
ACT_SITE   632    632        Charge relay system; for serine protease activity (By similarity). 
ACT_SITE   697    697        Charge relay system; for serine protease activity (By similarity). 
SITE   170    171  2     Cleavage (Potential). 
SITE   552    553  2     Cleavage (Potential). 
SITE   797    798  2     Cleavage (Potential). 
SITE   1051   1052  2     Cleavage (Potential). 
Sequence information
Length: 1638 AA [This is the length of the unprocessed precursor] Molecular weight: 187664 Da [This is the MW of the unprocessed precursor] CRC64: 941F4907479B6DB5 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAQAGRSGDA FASLDQRRER QEEQAQSGLD KVFYFQGVVE LFNRMKIAYG RTPAWTALMK 

        70         80         90        100        110        120 
CNAIYLKDFK TAVGVEGTRY GLFFAEEVTK PTWSPDIGAN LITLGEKACL DAQNAKYERL 

       130        140        150        160        170        180 
QASLKTTSGL VHQVMEKTRE AKENLEKANK IQEQLDKVIE SNKALHRKIQ ERNREKMQEY 

       190        200        210        220        230        240 
MVRLHNTQKD RDDWVQRCSR LEQENVTLQK RLKEKENALV SVGWDLLGWI VISVLVFGLI 

       250        260        270        280        290        300 
SLADAQNLTP PAKIVITPGQ AEFMDLAKLE KIQVRKYRLD SCELPPEKGC VLYKDYLTTR 

       310        320        330        340        350        360 
PVSFLELMAK CSKPDWVSES SYNETTLMEE CIQIFGAEWC EGKLVDLVPR KCGEQHVLVN 

       370        380        390        400        410        420 
IIEQIEKTRE VVTLIYGKVM SYRLDMWITS IFSLVLAGNK EKLFKMAPFI FVAWFLNIPV 

       430        440        450        460        470        480 
FLTCVAVNIF PVVSLPFILF QIFMPQFVLV NAFLLWLTLT LTAFYWSEGP KILMEISYAL 

       490        500        510        520        530        540 
VYTIGFVLWS LGLAVGVTLK LTMVHQILMF CVVAAAICGT KFACTTITVQ HPDGTTAKYT 

       550        560        570        580        590        600 
RVGKLKNNVV NQCKKVVTTL QTRGVIPATP AKTASIVIVE GKNGTGVGFR FMNYILTAEH 

       610        620        630        640        650        660 
VVQGSDIATL KNGSVSVKSK VIKTIPIFES VDNVAVLKLP PELNSVKPIK LAKKVQSDYL 

       670        680        690        700        710        720 
TLTAYDPNFQ HAATFTGWCI IDGNWLNNSF DTKFGNSGAP YCDHDGRLVG IHLGTQGVLS 

       730        740        750        760        770        780 
QGIVIVDALK NTFQLADQCR PQNFDMDEFL EKVIAGTKVS HAAILKELEE LREEVQFLKK 

       790        800        810        820        830        840 
KCVTYDDYWL CQTIFGQAKG KTKKTVRGRK HLVTKRALGK GHFMKMRMLT DEEYQNMIEK 

       850        860        870        880        890        900 
GFSAEEIREA VNALREQAWL NYCIDNDVDD EGEEDWYDDM VETDRVNQEI DEAIERAMED 

       910        920        930        940        950        960 
RGEFYQKKSR LTFVEQAMMH LIQVSKERSQ TAKLEVQKEN EAQLVKMFER CVTDENTPEG 

       970        980        990       1000       1010       1020 
TTSIAALSTE DDVRLVEGKV IDFTKAKNIP VDGEIRREII PGTKCTEIST GPENKKNILK 

      1030       1040       1050       1060       1070       1080 
KKDTHIAEGK VETKSSQQPV DVKDDKPVAL EQRKPRACKW CGSSQKHDYR ECRFQREKRF 

      1090       1100       1110       1120       1130       1140 
CVYCAAMHSM FEGHIRPIEC TSCKKSFSGI EKLEDHVVSG ECQKKLIEGP VTTKAPTPVP 

      1150       1160       1170       1180       1190       1200 
DWLKIFAWED DILPPEGKTA LPENVTLIGH IPVDKLVSRT KKVQDPLLGL VTPWKQDMYD 

      1210       1220       1230       1240       1250       1260 
STTWTVKAYT KMFEKFHYHD PVDFVEQYAE FVLLCDNMVL REHDYMANSN ITPIMSTEKN 

      1270       1280       1290       1300       1310       1320 
VNSTPAYPKF QAYDSEAEYL EDCGWQEYLD VVSDPETINR RPLWWCFLKN EVLKREKIED 

      1330       1340       1350       1360       1370       1380 
SDIRMILCTD PIFTRIGAMF EQDQNNRMKQ QTEIRSAQVG WTPFFGGLDR RVRRLYGDGD 

      1390       1400       1410       1420       1430       1440 
RYFVEMDWTR YDGTIPKSLF WRIRQIRFFF LHDSHKTPKM RRLYNWYVKN LLEKIILLPT 

      1450       1460       1470       1480       1490       1500 
GEVCQVKKGN PSGQFSTTVD NNMINVWLTT FEVSYLFFKQ RGRLPTEKEL QENCSMICYG 

      1510       1520       1530       1540       1550       1560 
DDRLLSIRKG FVEYEPDTVI DMYKNIFGMW VKRNNIKIQD TPEGLSFCGL TIVKSSTGAY 

      1570       1580       1590       1600       1610       1620 
VGVPNVNKIL STLENPVRRL PDVESLWGKL VSLRILCENA PSNVKHFLDE QISNVEEFAA 

      1630 
RENIQLPEVG PDFYSRIW
Q9ILI5 in FASTA format

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