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UniProtKB/Swiss-Prot entry Q9H819


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DJC18_HUMAN
Primary accession number Q9H819
Secondary accession numbers None
Integrated into Swiss-Prot on June 27, 2006
Sequence was last modified on March 1, 2001 (Sequence version 1)
Annotations were last modified on    June 16, 2009 (Entry version 54)
Name and origin of the protein
Protein name DnaJ homolog subfamily C member 18
Synonyms None
Gene name
Name: DNAJC18
From
Homo sapiens (Human) [TaxID: 9606] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
DOI=10.1038/ng1285; PubMed=14702039 [NCBI, ExPASy, EBI, Israel, Japan]
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
"Complete sequencing and characterization of 21,243 full-length human cDNAs.";
Nat. Genet. 36:40-45(2004).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Muscle;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AK024054; BAB14804.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BC030162; AAH30162.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
IPI IPI00025510; -.
RefSeq NP_689899.1; -.
UniGene Hs.483537
3D structure databases
HSSP P25685; 1HDJ. [HSSP ENTRY / PDB]
SMR Q9H819; 82-146.
ModBase Q9H819.
Organism-specific databases
GeneCards GC05M138776; -.
HGNC HGNC:28429; DNAJC18.
GenAtlas DNAJC18.
PharmGKB PA142671966; -.
Gene expression databases
ArrayExpress Q9H819; -.
Bgee Q9H819; -.
CleanEx HS_DNAJC18; -.
GermOnline ENSG00000170464; Homo sapiens.
Ontologies
GO
GO:0016021; Cellular component: integral to membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0031072; Molecular function: heat shock protein binding (inferred from electronic annotation from InterPro).
GO:0051082; Molecular function: unfolded protein binding (inferred from electronic annotation from InterPro).
GO:0006457; Biological process: protein folding (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR001623; DnaJ_N.
IPR015399; DUF1977_DnaJ-like.
IPR018253; Heat_shock_DnaJ_CS.
IPR015609; Hsp40/DnaJ_Rel.
IPR003095; Hsp_DnaJ.
Graphical view of domain structure.
Gene3D G3DSA:1.10.287.110; DnaJ_N; 1.
PANTHER PTHR11821; Hsp40/DnaJ_Rel; 1.
Pfam PF00226; DnaJ; 1.
PF09320; DUF1977; 1.
Pfam graphical view of domain structure.
PRINTS PR00625; DNAJPROTEIN.
SMART SM00271; DnaJ; 1.
SMART graphical view of domain structure.
PROSITE PS00636; DNAJ_1; 1.
PS50076; DNAJ_2; 1.
PROSITE graphical view of domain structure (profiles).
Proteomic databases
PRIDE Q9H819; -.
Genome annotation databases
Ensembl ENSG00000170464; Homo sapiens. [Contig view]
GeneID 202052; -.
KEGG hsa:202052; -.
Phylogenomic databases
HOGENOM Q9H819; -.
HOVERGEN Q9H819; -.
OMA Q9H819; PRARPYN.
Other
NextBio 90244; -.
ProtoNet Q9H819.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Chaperone; Membrane; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   358  358     DnaJ homolog subfamily C member 18. PRO_0000244085
TRANSMEM   228   248  21     Potential. 
DOMAIN   82   146  65     J. 
COMPBIAS   216   220  5     Poly-Glu. 
Sequence information
Length: 358 AA [This is the length of the unprocessed precursor] Molecular weight: 41551 Da [This is the MW of the unprocessed precursor] CRC64: BF8864DAB6D7695A [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAATLGSGER WTEAYIDAVR RNKYPEDTPP ESHDPCGCCN CMKAQKEKKS ENEWTQTRQG 

        70         80         90        100        110        120 
EGNSTYSEEQ LLGVQRIKKC RNYYEILGVS RDASDEELKK AYRKLALKFH PDKNCAPGAT 

       130        140        150        160        170        180 
DAFKAIGNAF AVLSNPDKRL RYDEYGDEQV TFTAPRARPY NYYRDFEADI TPEELFNVFF 

       190        200        210        220        230        240 
GGHFPTGNIH MFSNVTDDTY YYRRRHRHER TQTQKEEEEE KPQTTYSAFI QLLPVLVIVI 

       250        260        270        280        290        300 
ISVITQLLAT NPPYSLFYKS TLGYTISRET QNLQVPYFVD KNFDKAYRGA SLHDLEKTIE 

       310        320        330        340        350 
KDYIDYIQTS CWKEKQQKSE LTNLAGLYRD ERLKQKAESL KLENCEKLSK LIGLRRGG 

Q9H819 in FASTA format

View entry in raw text format (no links)
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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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NPSA logo NPSA Sequence analysis tools

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