[1]
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NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1A).
DOI=10.1182/blood.V98.7.2279; PubMed=11568019 [NCBI, ExPASy, EBI, Israel, Japan]
Gregorio-King C.C.,
Collier G.R.,
McMillan J.S.,
Waugh C.M.,
McLeod J.L.,
Collier F.M.,
Kirkland M.A.;
"ORP-3, a human oxysterol-binding protein gene differentially expressed in hematopoietic cells.";
Blood 98:2279-2281(2001).
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[2]
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NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1A).
DOI=10.1006/geno.2001.6663; PubMed=11735225 [NCBI, ExPASy, EBI, Israel, Japan]
Jaworski C.J.,
Moreira E.,
Li A.,
Lee R.,
Rodriguez I.R.;
"A family of 12 human genes containing oxysterol-binding domains.";
Genomics 78:185-196(2001).
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[3]
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NUCLEOTIDE SEQUENCE (ISOFORMS 1A; 1B; 1C; 1D; 2A; 2B; 2C AND 2D).
DOI=10.1089/104454903321112442; PubMed=12590732 [NCBI, ExPASy, EBI, Israel, Japan]
Collier F.M.,
Gregorio-King C.C.,
Apostolopoulos J.,
Walder K.,
Kirkland M.A.;
"ORP3 splice variants and their expression in human tissues and hematopoietic cells.";
DNA Cell Biol. 22:1-9(2003).
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[4]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1A).
TISSUE=Brain;
DOI=10.1093/dnares/5.3.169; PubMed=9734811 [NCBI, ExPASy, EBI, Israel, Japan]
Ishikawa K.,
Nagase T.,
Suyama M.,
Miyajima N.,
Tanaka A.,
Kotani H.,
Nomura N.,
Ohara O.;
"Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.";
DNA Res. 5:169-176(1998).
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[5]
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SEQUENCE REVISION.
Ohara O.,
Suyama M.,
Nagase T.,
Ishikawa K.;
Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
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[6]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nature01782; PubMed=12853948 [NCBI, ExPASy, EBI, Israel, Japan]
Hillier L.W.,
Fulton R.S.,
Fulton L.A.,
Graves T.A.,
Pepin K.H.,
Wagner-McPherson C.,
Layman D.,
Maas J.,
Jaeger S.,
Walker R.,
Wylie K.,
Sekhon M.,
Becker M.C.,
O'Laughlin M.D.,
Schaller M.E.,
Fewell G.A.,
Delehaunty K.D.,
Miner T.L.,
Nash W.E., ![]()
Cordes M.,
Du H.,
Sun H.,
Edwards J.,
Bradshaw-Cordum H.,
Ali J.,
Andrews S.,
Isak A.,
Vanbrunt A.,
Nguyen C.,
Du F.,
Lamar B.,
Courtney L.,
Kalicki J.,
Ozersky P.,
Bielicki L.,
Scott K.,
Holmes A.,
Harkins R.,
Harris A.,
Strong C.M.,
Hou S.,
Tomlinson C.,
Dauphin-Kohlberg S.,
Kozlowicz-Reilly A.,
Leonard S.,
Rohlfing T.,
Rock S.M.,
Tin-Wollam A.-M.,
Abbott A.,
Minx P.,
Maupin R.,
Strowmatt C.,
Latreille P.,
Miller N.,
Johnson D.,
Murray J.,
Woessner J.P.,
Wendl M.C.,
Yang S.-P.,
Schultz B.R.,
Wallis J.W.,
Spieth J.,
Bieri T.A.,
Nelson J.O.,
Berkowicz N.,
Wohldmann P.E.,
Cook L.L.,
Hickenbotham M.T.,
Eldred J.,
Williams D.,
Bedell J.A.,
Mardis E.R.,
Clifton S.W.,
Chissoe S.L.,
Marra M.A.,
Raymond C.,
Haugen E.,
Gillett W.,
Zhou Y.,
James R.,
Phelps K.,
Iadanoto S.,
Bubb K.,
Simms E.,
Levy R.,
Clendenning J.,
Kaul R.,
Kent W.J.,
Furey T.S.,
Baertsch R.A.,
Brent M.R.,
Keibler E.,
Flicek P.,
Bork P.,
Suyama M.,
Bailey J.A.,
Portnoy M.E.,
Torrents D.,
Chinwalla A.T.,
Gish W.R.,
Eddy S.R.,
McPherson J.D.,
Olson M.V.,
Eichler E.E.,
Green E.D.,
Waterston R.H.,
Wilson R.K.;
"The DNA sequence of human chromosome 7.";
Nature 424:157-164(2003).
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[7]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1A).
TISSUE=Uterus;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[8]
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NUCLEOTIDE SEQUENCE OF 1-245 (ISOFORM 1A).
PubMed=11483621 [NCBI, ExPASy, EBI, Israel, Japan]
Lehto M.,
Laitinen S.,
Chinetti G.,
Johansson M.,
Ehnholm C.,
Staels B.,
Ikonen E.,
Olkkonen V.M.;
"The OSBP-related protein family in humans.";
J. Lipid Res. 42:1203-1213(2001).
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[9]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-437, AND MASS SPECTROMETRY.
TISSUE=Platelet;
DOI=10.1021/pr0704130; PubMed=18088087 [NCBI, ExPASy, EBI, Israel, Japan]
Zahedi R.P.,
Lewandrowski U.,
Wiesner J.,
Wortelkamp S.,
Moebius J.,
Schuetz C.,
Walter U.,
Gambaryan S.,
Sickmann A.;
"Phosphoproteome of resting human platelets.";
J. Proteome Res. 7:526-534(2008).
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- INTERACTION:
P31946:YWHAB; NbExp=1; IntAct=EBI-1051317, EBI-359815;
P61981:YWHAG; NbExp=1; IntAct=EBI-1051317, EBI-359832;
- ALTERNATIVE PRODUCTS:
8 named isoforms [FASTA] produced by alternative splicing.
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| Name | 1b |
| Isoform ID | Q9H4L5-2 |
| Features which should be applied to build the isoform sequence: VSP_008219. |
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| Name | 1c |
| Isoform ID | Q9H4L5-3 |
| Features which should be applied to build the isoform sequence: VSP_008220. |
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- TISSUE SPECIFICITY: Isoforms 1a, 1b, 1c and 1d are highly expressed in brain, bone marrow, colon, kidney, lung, skeletal muscle, spleen, thymus and thyroid, but are not expressed in heart and liver. Isoforms 2a, 2b, 2c and 2d are expressed in brain, bone marrow, kidney, skeletal muscle, spleen, thymus and thyroid, but are not expressed in heart, liver and lung.
- SIMILARITY: Belongs to the OSBP family.
- SIMILARITY: Contains 1 PH domain.
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