[1]
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NUCLEOTIDE SEQUENCE [MRNA], AND INTERACTION WITH UFO.
STRAIN=cv. Columbia;
DOI=10.1046/j.1365-313x.1999.00617.x; PubMed=10607296 [NCBI, ExPASy, EBI, Israel, Japan]
Samach A.,
Klenz J.E.,
Kohalmi S.E.,
Risseeuw E.,
Haughn G.W.,
Crosby W.L.;
"The UNUSUAL FLORAL ORGANS gene of Arabidopsis thaliana is an F-box protein required for normal patterning and growth in the floral meristem.";
Plant J. 20:433-445(1999).
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[2]
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NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=cv. Landsberg erecta;
DOI=10.1007/s004380051173; PubMed=10778750 [NCBI, ExPASy, EBI, Israel, Japan]
Schouten J.,
de Kam R.J.,
Fetter K.,
Hoge J.H.C.;
"Overexpression of Arabidopsis thaliana SKP1 homologues in yeast inactivates the Mig1 repressor by destabilising the F-box protein Grr1.";
Mol. Gen. Genet. 263:309-319(2000).
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[3]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1093/dnares/5.2.131; PubMed=9679202 [NCBI, ExPASy, EBI, Israel, Japan]
Kaneko T.,
Kotani H.,
Nakamura Y.,
Sato S.,
Asamizu E.,
Miyajima N.,
Tabata S.;
"Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.";
DNA Res. 5:131-145(1998).
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[4]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K.,
Lim J.,
Dale J.M.,
Chen H.,
Shinn P.,
Palm C.J.,
Southwick A.M.,
Wu H.C.,
Kim C.J.,
Nguyen M.,
Pham P.K.,
Cheuk R.F.,
Karlin-Newmann G.,
Liu S.X.,
Lam B.,
Sakano H.,
Wu T.,
Yu G.,
Miranda M., ![]()
Quach H.L.,
Tripp M.,
Chang C.H.,
Lee J.M.,
Toriumi M.J.,
Chan M.M.,
Tang C.C.,
Onodera C.S.,
Deng J.M.,
Akiyama K.,
Ansari Y.,
Arakawa T.,
Banh J.,
Banno F.,
Bowser L.,
Brooks S.Y.,
Carninci P.,
Chao Q.,
Choy N.,
Enju A.,
Goldsmith A.D.,
Gurjal M.,
Hansen N.F.,
Hayashizaki Y.,
Johnson-Hopson C.,
Hsuan V.W.,
Iida K.,
Karnes M.,
Khan S.,
Koesema E.,
Ishida J.,
Jiang P.X.,
Jones T.,
Kawai J.,
Kamiya A.,
Meyers C.,
Nakajima M.,
Narusaka M.,
Seki M.,
Sakurai T.,
Satou M.,
Tamse R.,
Vaysberg M.,
Wallender E.K.,
Wong C.,
Yamamura Y.,
Yuan S.,
Shinozaki K.,
Davis R.W.,
Theologis A.,
Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
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[5]
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FUNCTION, AND INTERACTION WITH TIR1.
DOI=10.1101/gad.13.13.1678; PubMed=10398681 [NCBI, ExPASy, EBI, Israel, Japan]
Gray W.M.,
del Pozo J.C.,
Walker L.,
Hobbie L.,
Risseeuw E.,
Banks T.,
Crosby W.L.,
Yang M.,
Ma H.,
Estelle M.;
"Identification of an SCF ubiquitin-ligase complex required for auxin response in Arabidopsis thaliana.";
Genes Dev. 13:1678-1691(1999).
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[6]
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INTERACTION WITH EID1.
DOI=10.1101/gad.197201; PubMed=11316788 [NCBI, ExPASy, EBI, Israel, Japan]
Dieterle M.,
Zhou Y.-C.,
Schaefer E.,
Funk M.,
Kretsch T.;
"EID1, an F-box protein involved in phytochrome A-specific light signaling.";
Genes Dev. 15:939-944(2001).
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[7]
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IDENTIFICATION IN A SCF COMPLEX.
DOI=10.1074/jbc.M204254200; PubMed=12381738 [NCBI, ExPASy, EBI, Israel, Japan]
Lechner E.,
Xie D.,
Grava S.,
Pigaglio E.,
Planchais S.,
Murray J.A.H.,
Parmentier Y.,
Mutterer J.,
Dubreucq B.,
Shen W.-H.,
Genschik P.;
"The AtRbx1 protein is part of plant SCF complexes, and its down-regulation causes severe growth and developmental defects.";
J. Biol. Chem. 277:50069-50080(2002).
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[8]
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INTERACTION WITH COI1, AND IDENTIFICATION IN A SCF(COI1) COMPLEX.
DOI=10.1105/tpc.003368; PubMed=12172031 [NCBI, ExPASy, EBI, Israel, Japan]
Xu L.,
Liu F.,
Lechner E.,
Genschik P.,
Crosby W.L.,
Ma H.,
Peng W.,
Huang D.,
Xie D.;
"The SCF(COI1) ubiquitin-ligase complexes are required for jasmonate response in Arabidopsis.";
Plant Cell 14:1919-1935(2002).
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[9]
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INTERACTION WITH COI1, AND IDENTIFICATION IN A SCF(COI1) COMPLEX.
DOI=10.1046/j.1365-313X.2002.01432.x; PubMed=12445118 [NCBI, ExPASy, EBI, Israel, Japan]
Devoto A.,
Nieto-Rostro M.,
Xie D.,
Ellis C.,
Harmston R.,
Patrick E.,
Davis J.,
Sherratt L.,
Coleman M.,
Turner J.G.;
"COI1 links jasmonate signalling and fertility to the SCF ubiquitin-ligase complex in Arabidopsis.";
Plant J. 32:457-466(2002).
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[10]
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FUNCTION, AND TISSUE SPECIFICITY.
DOI=10.1104/pp.103.024703; PubMed=12970487 [NCBI, ExPASy, EBI, Israel, Japan]
Zhao D.,
Ni W.,
Feng B.,
Han T.,
Petrasek M.G.,
Ma H.;
"Members of the Arabidopsis-SKP1-like gene family exhibit a variety of expression patterns and may play diverse roles in Arabidopsis.";
Plant Physiol. 133:203-217(2003).
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[11]
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INTERACTION WITH ADO1; ADO2 AND ADO3.
DOI=10.1093/jxb/erh226; PubMed=15310821 [NCBI, ExPASy, EBI, Israel, Japan]
Yasuhara M.,
Mitsui S.,
Hirano H.,
Takanabe R.,
Tokioka Y.,
Ihara N.,
Komatsu A.,
Seki M.,
Shinozaki K.,
Kiyosue T.;
"Identification of ASK and clock-associated proteins as molecular partners of LKP2 (LOV kelch protein 2) in Arabidopsis.";
J. Exp. Bot. 55:2015-2027(2004).
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[12]
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FUNCTION, TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
DOI=10.1105/tpc.017772; PubMed=14688296 [NCBI, ExPASy, EBI, Israel, Japan]
Liu F.,
Ni W.,
Griffith M.E.,
Huang Z.,
Chang C.,
Peng W.,
Ma H.,
Xie D.;
"The ASK1 and ASK2 genes are essential for Arabidopsis early development.";
Plant Cell 16:5-20(2004).
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[13]
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INTERACTION WITH ADO1.
DOI=10.1111/j.1365-313X.2004.02207.x; PubMed=15447654 [NCBI, ExPASy, EBI, Israel, Japan]
Han L.,
Mason M.,
Risseeuw E.P.,
Crosby W.L.,
Somers D.E.;
"Formation of an SCF(ZTL) complex is required for proper regulation of circadian timing.";
Plant J. 40:291-301(2004).
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- FUNCTION: Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends of the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1. SCF(UFO) is required for vegetative and floral organ development as well as for male gametogenesis. SCF(TIR1) is involved in auxin signaling pathway. SCF(COI1) regulates responses to jasmonates. SCF(EID1) and SCF(AFR) are implicated in phytochrome A light signaling. SCF(ADO1), SCF(ADO2), SCF(ADO3) are related to the circadian clock. SCF(ORE9) seems to be involved in senescence. SCF(EBF1/EBF2) may regulate ethylene signaling. Plays a role during embryogenesis and early postembryonic development, especially during cell elongation and division. Contributes to the correct chromosome segregation during tetrad formation.
- PATHWAY: Protein modification; protein ubiquitination.
- SUBUNIT: Part of a SCF E3 ubiquitin ligase complex composed of SKP1, CUL1, RBX1 (RBX1A or RBX1B) and F-box proteins such as UFO, EID1, ADO1/ZTL, ADO2/LKP2, ADO3/FKF1, COI1 and TIR1. The SKP1B subunit of the SCF E3 ubiquitin ligase complex can probably interact directly with KIN10, KIN11 and the proteasome subunit PAD1. May also interact with SKIP1, SKIP2, SKIP3, SKIP4, SKIP6 and FIB1/SKIP7, AFR, ORE9, EBF1 and EBF2.
- INTERACTION:
Q0WRC9:-; NbExp=2; IntAct=EBI-604076, EBI-604757;
Q65967:- (xeno); NbExp=3; IntAct=EBI-604076, EBI-848577;
Q9LU91:-; NbExp=2; IntAct=EBI-604076, EBI-604313;
Q94BT6:ADO1; NbExp=2; IntAct=EBI-604076, EBI-300691;
Q9C9W9:ADO3; NbExp=2; IntAct=EBI-604076, EBI-401228;
Q9ZU90:At2g01620/T8O11.21; NbExp=2; IntAct=EBI-604076, EBI-604427;
O04197:COI1; NbExp=5; IntAct=EBI-604076, EBI-401159;
Q9SKK0:EBF1; NbExp=3; IntAct=EBI-604076, EBI-401198;
Q8LEA8:EID1; NbExp=2; IntAct=EBI-604076, EBI-687388;
Q9M0U9:FBL20; NbExp=2; IntAct=EBI-604076, EBI-604728;
Q9XI00:FBP7; NbExp=2; IntAct=EBI-604076, EBI-591127;
Q9ZPE4:FBW2; NbExp=2; IntAct=EBI-604076, EBI-604740;
O49279:FBX3; NbExp=3; IntAct=EBI-604076, EBI-591174;
Q9STX3:GID2; NbExp=1; IntAct=EBI-604076, EBI-619033;
Q9LEX0:PP2A13; NbExp=3; IntAct=EBI-604076, EBI-604261;
Q9FJ80:PP2A14; NbExp=2; IntAct=EBI-604076, EBI-604303;
Q9FDX1:SKIP1; NbExp=2; IntAct=EBI-604076, EBI-604228;
Q9LND7:T21E18.16; NbExp=2; IntAct=EBI-604076, EBI-591078;
Q570C0:TIR1; NbExp=4; IntAct=EBI-604076, EBI-307183;
Q39090:UFO; NbExp=2; IntAct=EBI-604076, EBI-590758;
P15597:virF (xeno); NbExp=4; IntAct=EBI-604076, EBI-605118;
- SUBCELLULAR LOCATION: Nucleus (By similarity).
- TISSUE SPECIFICITY: Expressed in tips, cortical layer and epidermis of roots. Detected in whole seedling, vascular tissues, pith and vascular bundle of young stem, leaves, inflorescence meristem, young floral buds and organ primordia, flowers, developing seeds and through the valve of siliques. Expressed in male meiocytes, pollen, embryo and endosperm.
- DEVELOPMENTAL STAGE: Expressed during all stages of embryogenesis.
- SIMILARITY: Belongs to the SKP1 family.
- WEB RESOURCE: Name=PlantsUBQ; Note=A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants; URL="http://plantsubq.genomics.purdue.edu/";.
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