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UniProtKB/Swiss-Prot entry Q9CGG8

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name LDH3_LACLA
Primary accession number Q9CGG8
Secondary accession numbers None
Integrated into Swiss-Prot on June 21, 2004
Sequence was last modified on June 1, 2001 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 45)
Name and origin of the protein
Protein name L-lactate dehydrogenase 3
Synonyms L-LDH 3
EC 1.1.1.27
Gene name
Name: ldhX
OrderedLocusNames: LL1128
ORFNames: L142159
From
Lactococcus lactis subsp. lactis (Streptococcus lactis) [TaxID: 1360] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Lactococcus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=IL1403;
DOI=10.1101/gr.GR-1697R; PubMed=11337471 [NCBI, ExPASy, EBI, Israel, Japan]
Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J., Ehrlich S.D., Sorokin A.;
"The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403.";
Genome Res. 11:731-753(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE006345; AAK05226.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR H86765; H86765.
RefSeq NP_267284.1; -.
3D structure databases
HSSP P00344; 2LDB. [HSSP ENTRY / PDB]
ModBase Q9CGG8.
Enzyme and pathway databases
BioCyc LLAC272623:L142159-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004459; Molecular function: L-lactate dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0019642; Biological process: anaerobic glycolysis (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00488; -; 1.
PBIL [Tree]
InterPro IPR001557; L-lactate/malate_DHase.
IPR011304; L-lactate_DHase.
IPR001236; Lactate/malate_DHase.
IPR015955; Lactate_DHase/Glyco_Ohase_4_C.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.90.110.10; lact_mal_DH; 1.
G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF02866; Ldh_1_C; 1.
PF00056; Ldh_1_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000102; Lac_mal_DH; 1.
PRINTS PR00086; LLDHDRGNASE.
TIGRFAMs TIGR01771; L-LDH-NAD; 1.
PROSITE PS00064; L_LDH; FALSE_NEG.
BLOCKS Q9CGG8.
Genome annotation databases
GeneID 1114768; -.
GenomeReviews AE005176_GR; LL1128.
KEGG lla:L142159; -.
NMPDR fig|272623.1.peg.1160; -.
Phylogenomic databases
HOGENOM Q9CGG8; -.
Genome annotation databases
CMR Q9CGG8; LL1128.
Other
ProtoNet Q9CGG8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Glycolysis; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   323  323     L-lactate dehydrogenase 3. PRO_0000168353
NP_BIND   14    42  29     NAD (By similarity). 
ACT_SITE   182   182        Proton acceptor (By similarity). 
BINDING   95    95        Substrate (By similarity). 
BINDING   127   127        NAD or substrate (By similarity). 
BINDING   158   158        Substrate (By similarity). 
BINDING   236   236        Substrate (By similarity). 
Sequence information
Length: 323 AA [This is the length of the unprocessed precursor] Molecular weight: 35271 Da [This is the MW of the unprocessed precursor] CRC64: 87CCB4EA290A15DD [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MKINNKKVVI VGAGAVGSTY AHNLVVDDLA DEIAIINTNK SKASANSLDL LHALPYLNAA 

        70         80         90        100        110        120 
PKNIYAADYS DVSDADIVVL SANAPSATFG KNPDRLQLLE NKVEMIRDIT RKTMDAGFDG 

       130        140        150        160        170        180 
IFLVASNPVD VLAQVVAEVS GLPKHRVIGT GTLLETSRMR QIVAEKLQIN PKSIHGYVLA 

       190        200        210        220        230        240 
EHGKSSFAAW SNVTVGAIPL TTWLKKYPNP EFPTFDEIDQ EIREVGLDIF MQKGNTSYGI 

       250        260        270        280        290        300 
AASLARLTRA IFRNESVILP VSAYLTGEYG QFDLYTGSPA IIDRTGVRAV LELELTQEEQ 

       310        320 
EKFKASTVLL KENFDSIKEK CTL
Q9CGG8 in FASTA format

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