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[1]
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NUCLEOTIDE SEQUENCE [MRNA], AND INDUCTION.
TISSUE=Skin;
DOI=10.1111/1523-1747.ep12276660; PubMed=9204961 [NCBI, ExPASy, EBI, Israel, Japan]
Nagpal S.,
Patel S.,
Jacobe H.,
DiSepio D.,
Ghosn C.,
Malhotra M.,
Teng M.,
Duvic M.,
Chandraratna R.A.S.;
"Tazarotene-induced gene 2 (TIG2), a novel retinoid-responsive gene in skin.";
J. Invest. Dermatol. 109:91-95(1997).
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[2]
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NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Gastric adenocarcinoma;
DOI=10.1016/S0378-1119(99)00004-9; PubMed=10072769 [NCBI, ExPASy, EBI, Israel, Japan]
Yokoyama-Kobayashi M.,
Yamaguchi T.,
Sekine S.,
Kato S.;
"Selection of cDNAs encoding putative type II membrane proteins on the cell surface from a human full-length cDNA bank.";
Gene 228:161-167(1999).
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[3]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Kidney;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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- SUBCELLULAR LOCATION: Secreted (Potential).
- TISSUE SPECIFICITY: Highly expressed in skin (basal and suprabasal layers of the epidermis, hair follicles and endothelial cells). Also found in pancreas, liver, spleen, prostate, ovary, small intestine and colon.
- INDUCTION: Inhibited in psoriatic lesions. Activated by tazarotene in skin rafts and in the epidermis of psoriatic lesions.
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 163 AA [This is the length of the unprocessed precursor] |
Molecular weight: 18618 Da [This is the MW of the unprocessed precursor] |
CRC64: A96EB7D0999EC3DB [This is a checksum on the sequence] |
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10 20 30 40 50 60
MRRLLIPLAL WLGAVGVGVA ELTEAQRRGL QVALEEFHKH PPVQWAFQET SVESAVDTPF
70 80 90 100 110 120
PAGIFVRLEF KLQQTSCRKR DWKKPECKVR PNGRKRKCLA CIKLGSEDKV LGRLVHCPIE
130 140 150 160
TQVLREAEEH QETQCLRVQR AGEDPHSFYF PGQFAFSKAL PRS
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Q99969 in FASTA format |
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