[1]
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NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), AND FUNCTION.
DOI=10.1074/jbc.272.5.2668; PubMed=9006902 [NCBI, ExPASy, EBI, Israel, Japan]
Ellinger-Ziegelbauer H.C.,
Brown K.,
Kelly K.,
Siebenlist U.;
"Direct activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein kinase/ERK kinase kinase 3 (MEKK) derivative.";
J. Biol. Chem. 272:2668-2674(1997).
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[2]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
TISSUE=Placenta;
DOI=10.1038/ng1285; PubMed=14702039 [NCBI, ExPASy, EBI, Israel, Japan]
Ota T.,
Suzuki Y.,
Nishikawa T.,
Otsuki T.,
Sugiyama T.,
Irie R.,
Wakamatsu A.,
Hayashi K.,
Sato H.,
Nagai K.,
Kimura K.,
Makita H.,
Sekine M.,
Obayashi M.,
Nishi T.,
Shibahara T.,
Tanaka T.,
Ishii S.,
Yamamoto J., ![]()
Saito K.,
Kawai Y.,
Isono Y.,
Nakamura Y.,
Nagahari K.,
Murakami K.,
Yasuda T.,
Iwayanagi T.,
Wagatsuma M.,
Shiratori A.,
Sudo H.,
Hosoiri T.,
Kaku Y.,
Kodaira H.,
Kondo H.,
Sugawara M.,
Takahashi M.,
Kanda K.,
Yokoi T.,
Furuya T.,
Kikkawa E.,
Omura Y.,
Abe K.,
Kamihara K.,
Katsuta N.,
Sato K.,
Tanikawa M.,
Yamazaki M.,
Ninomiya K.,
Ishibashi T.,
Yamashita H.,
Murakawa K.,
Fujimori K.,
Tanai H.,
Kimata M.,
Watanabe M.,
Hiraoka S.,
Chiba Y.,
Ishida S.,
Ono Y.,
Takiguchi S.,
Watanabe S.,
Yosida M.,
Hotuta T.,
Kusano J.,
Kanehori K.,
Takahashi-Fujii A.,
Hara H.,
Tanase T.-O.,
Nomura Y.,
Togiya S.,
Komai F.,
Hara R.,
Takeuchi K.,
Arita M.,
Imose N.,
Musashino K.,
Yuuki H.,
Oshima A.,
Sasaki N.,
Aotsuka S.,
Yoshikawa Y.,
Matsunawa H.,
Ichihara T.,
Shiohata N.,
Sano S.,
Moriya S.,
Momiyama H.,
Satoh N.,
Takami S.,
Terashima Y.,
Suzuki O.,
Nakagawa S.,
Senoh A.,
Mizoguchi H.,
Goto Y.,
Shimizu F.,
Wakebe H.,
Hishigaki H.,
Watanabe T.,
Sugiyama A.,
Takemoto M.,
Kawakami B.,
Yamazaki M.,
Watanabe K.,
Kumagai A.,
Itakura S.,
Fukuzumi Y.,
Fujimori Y.,
Komiyama M.,
Tashiro H.,
Tanigami A.,
Fujiwara T.,
Ono T.,
Yamada K.,
Fujii Y.,
Ozaki K.,
Hirao M.,
Ohmori Y.,
Kawabata A.,
Hikiji T.,
Kobatake N.,
Inagaki H.,
Ikema Y.,
Okamoto S.,
Okitani R.,
Kawakami T.,
Noguchi S.,
Itoh T.,
Shigeta K.,
Senba T.,
Matsumura K.,
Nakajima Y.,
Mizuno T.,
Morinaga M.,
Sasaki M.,
Togashi T.,
Oyama M.,
Hata H.,
Watanabe M.,
Komatsu T.,
Mizushima-Sugano J.,
Satoh T.,
Shirai Y.,
Takahashi Y.,
Nakagawa K.,
Okumura K.,
Nagase T.,
Nomura N.,
Kikuchi H.,
Masuho Y.,
Yamashita R.,
Nakai K.,
Yada T.,
Nakamura Y.,
Ohara O.,
Isogai T.,
Sugano S.;
"Complete sequencing and characterization of 21,243 full-length human cDNAs.";
Nat. Genet. 36:40-45(2004).
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[3]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
TISSUE=Melanoma;
DOI=10.1186/1471-2164-8-399; PubMed=17974005 [NCBI, ExPASy, EBI, Israel, Japan]
Bechtel S.,
Rosenfelder H.,
Duda A.,
Schmidt C.P.,
Ernst U.,
Wellenreuther R.,
Mehrle A.,
Schuster C.,
Bahr A.,
Blocker H.,
Heubner D.,
Hoerlein A.,
Michel G.,
Wedler H.,
Kohrer K.,
Ottenwalder B.,
Poustka A.,
Wiemann S.,
Schupp I.;
"The full-ORF clone resource of the German cDNA consortium.";
BMC Genomics 8:399-399(2007).
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[4]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nature04689; PubMed=16625196 [NCBI, ExPASy, EBI, Israel, Japan]
Zody M.C.,
Garber M.,
Adams D.J.,
Sharpe T.,
Harrow J.,
Lupski J.R.,
Nicholson C.,
Searle S.M.,
Wilming L.,
Young S.K.,
Abouelleil A.,
Allen N.R.,
Bi W.,
Bloom T.,
Borowsky M.L.,
Bugalter B.E.,
Butler J.,
Chang J.L.,
Chen C.-K., ![]()
Cook A.,
Corum B.,
Cuomo C.A.,
de Jong P.J.,
DeCaprio D.,
Dewar K.,
FitzGerald M.,
Gilbert J.,
Gibson R.,
Gnerre S.,
Goldstein S.,
Grafham D.V.,
Grocock R.,
Hafez N.,
Hagopian D.S.,
Hart E.,
Norman C.H.,
Humphray S.,
Jaffe D.B.,
Jones M.,
Kamal M.,
Khodiyar V.K.,
LaButti K.,
Laird G.,
Lehoczky J.,
Liu X.,
Lokyitsang T.,
Loveland J.,
Lui A.,
Macdonald P.,
Major J.E.,
Matthews L.,
Mauceli E.,
McCarroll S.A.,
Mihalev A.H.,
Mudge J.,
Nguyen C.,
Nicol R.,
O'Leary S.B.,
Osoegawa K.,
Schwartz D.C.,
Shaw-Smith C.,
Stankiewicz P.,
Steward C.,
Swarbreck D.,
Venkataraman V.,
Whittaker C.A.,
Yang X.,
Zimmer A.R.,
Bradley A.,
Hubbard T.,
Birren B.W.,
Rogers J.,
Lander E.S.,
Nusbaum C.;
"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.";
Nature 440:1045-1049(2006).
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[5]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Mural R.J.,
Istrail S.,
Sutton G.G.,
Florea L.,
Halpern A.L.,
Mobarry C.M.,
Lippert R.,
Walenz B.,
Shatkay H.,
Dew I.,
Miller J.R.,
Flanigan M.J.,
Edwards N.J.,
Bolanos R.,
Fasulo D.,
Halldorsson B.V.,
Hannenhalli S.,
Turner R.,
Yooseph S., ![]()
Lu F.,
Nusskern D.R.,
Shue B.C.,
Zheng X.H.,
Zhong F.,
Delcher A.L.,
Huson D.H.,
Kravitz S.A.,
Mouchard L.,
Reinert K.,
Remington K.A.,
Clark A.G.,
Waterman M.S.,
Eichler E.E.,
Adams M.D.,
Hunkapiller M.W.,
Myers E.W.,
Venter J.C.;
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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[6]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
TISSUE=Brain, and PNS;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[7]
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FUNCTION, AND INTERACTION WITH MAP2K5.
DOI=10.1074/jbc.C300313200; PubMed=12912994 [NCBI, ExPASy, EBI, Israel, Japan]
Nakamura K.,
Johnson G.L.;
"PB1 domains of MEKK2 and MEKK3 interact with the MEK5 PB1 domain for activation of the ERK5 pathway.";
J. Biol. Chem. 278:36989-36992(2003).
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[8]
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FUNCTION, AND INTERACTION WITH TRAF6.
DOI=10.1038/ni1014; PubMed=14661019 [NCBI, ExPASy, EBI, Israel, Japan]
Huang Q.,
Yang J.,
Lin Y.,
Walker C.,
Cheng J.,
Liu Z.G.,
Su B.;
"Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3.";
Nat. Immunol. 5:98-103(2004).
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[9]
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FUNCTION, AND INTERACTION WITH TRAF7.
DOI=10.1038/ncb1086; PubMed=14743216 [NCBI, ExPASy, EBI, Israel, Japan]
Bouwmeester T.,
Bauch A.,
Ruffner H.,
Angrand P.-O.,
Bergamini G.,
Croughton K.,
Cruciat C.,
Eberhard D.,
Gagneur J.,
Ghidelli S.,
Hopf C.,
Huhse B.,
Mangano R.,
Michon A.-M.,
Schirle M.,
Schlegl J.,
Schwab M.,
Stein M.A.,
Bauer A., ![]()
Casari G.,
Drewes G.,
Gavin A.-C.,
Jackson D.B.,
Joberty G.,
Neubauer G.,
Rick J.,
Kuster B.,
Superti-Furga G.;
"A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.";
Nat. Cell Biol. 6:97-105(2004).
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[10]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-288; SER-289 AND THR-294, AND MASS SPECTROMETRY.
TISSUE=Epithelium;
DOI=10.1021/pr070152u; PubMed=17924679 [NCBI, ExPASy, EBI, Israel, Japan]
Yu L.-R.,
Zhu Z.,
Chan K.C.,
Issaq H.J.,
Dimitrov D.S.,
Veenstra T.D.;
"Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.";
J. Proteome Res. 6:4150-4162(2007).
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[11]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-166, AND MASS SPECTROMETRY.
DOI=10.1021/pr0705441; PubMed=18220336 [NCBI, ExPASy, EBI, Israel, Japan]
Cantin G.T.,
Yi W.,
Lu B.,
Park S.K.,
Xu T.,
Lee J.-D.,
Yates J.R. III;
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.";
J. Proteome Res. 7:1346-1351(2008).
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[12]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-131; SER-166; SER-234; SER-237; SER-250; SER-337; SER-340 AND SER-355, AND MASS SPECTROMETRY.
DOI=10.1016/j.molcel.2008.07.007; PubMed=18691976 [NCBI, ExPASy, EBI, Israel, Japan]
Daub H.,
Olsen J.V.,
Bairlein M.,
Gnad F.,
Oppermann F.S.,
Korner R.,
Greff Z.,
Keri G.,
Stemmann O.,
Mann M.;
"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.";
Mol. Cell 31:438-448(2008).
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[13]
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VARIANT [LARGE SCALE ANALYSIS] MET-281.
DOI=10.1038/nature05610; PubMed=17344846 [NCBI, ExPASy, EBI, Israel, Japan]
Greenman C.,
Stephens P.,
Smith R.,
Dalgliesh G.L.,
Hunter C.,
Bignell G.,
Davies H.,
Teague J.,
Butler A.,
Stevens C.,
Edkins S.,
O'Meara S.,
Vastrik I.,
Schmidt E.E.,
Avis T.,
Barthorpe S.,
Bhamra G.,
Buck G.,
Choudhury B., ![]()
Clements J.,
Cole J.,
Dicks E.,
Forbes S.,
Gray K.,
Halliday K.,
Harrison R.,
Hills K.,
Hinton J.,
Jenkinson A.,
Jones D.,
Menzies A.,
Mironenko T.,
Perry J.,
Raine K.,
Richardson D.,
Shepherd R.,
Small A.,
Tofts C.,
Varian J.,
Webb T.,
West S.,
Widaa S.,
Yates A.,
Cahill D.P.,
Louis D.N.,
Goldstraw P.,
Nicholson A.G.,
Brasseur F.,
Looijenga L.,
Weber B.L.,
Chiew Y.-E.,
DeFazio A.,
Greaves M.F.,
Green A.R.,
Campbell P.,
Birney E.,
Easton D.F.,
Chenevix-Trench G.,
Tan M.-H.,
Khoo S.K.,
Teh B.T.,
Yuen S.T.,
Leung S.Y.,
Wooster R.,
Futreal P.A.,
Stratton M.R.;
"Patterns of somatic mutation in human cancer genomes.";
Nature 446:153-158(2007).
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