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UniProtKB/Swiss-Prot entry Q98267


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NTP1_MCV1
Primary accession number Q98267
Secondary accession numbers None
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on February 1, 1997 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 44)
Name and origin of the protein
Protein name Nucleoside triphosphatase I
Synonyms EC 3.6.1.15
Nucleoside triphosphate phosphohydrolase I
NPH I
Gene name
Name: NPH1
OrderedLocusNames: MC100L
From
Molluscum contagiosum virus subtype 1 (MOCV) (MCVI) [TaxID: 10280] 
Taxonomy Viruses; dsDNA viruses, no RNA stage; Poxviridae; Chordopoxvirinae; Molluscipoxvirus.
Virus host Homo sapiens (Human) [TaxID: 9606]
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=8670425 [NCBI, ExPASy, EBI, Israel, Japan]
Senkevich T.G., Bugert J.J., Sisler J.R., Koonin E.V., Darai G., Moss B.;
"Genome sequence of a human tumorigenic poxvirus: prediction of specific host response-evasion genes.";
Science 273:813-816(1996).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U60315; AAC55228.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T30702; T30702.
RefSeq NP_044051.1; -.
3D structure databases
ModBase Q98267.
Family and domain databases
InterPro IPR014001; DEAD-like_N.
IPR001650; DNA/RNA_helicase_C.
IPR014021; Helicase_SF1/SF2_ATP-bd.
IPR013676; NPHI_C.
IPR000330; SNF2_N.
Graphical view of domain structure.
Pfam PF00271; Helicase_C; 1.
PF08469; NPHI_C; 1.
PF00176; SNF2_N; 1.
Pfam graphical view of domain structure.
SMART SM00487; DEXDc; 1.
SM00490; HELICc; 1.
SMART graphical view of domain structure.
PROSITE PS51192; HELICASE_ATP_BIND_1; 1.
PS51194; HELICASE_CTER; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q98267.
Genome annotation databases
GeneID 1487119; -.
Other
ProtoNet Q98267.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Hydrolase; Nucleotide-binding; Transcription.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   634  634     Nucleoside triphosphatase I. PRO_0000099104
DOMAIN   41   203  163     Helicase ATP-binding. 
DOMAIN   355   531  177     Helicase C-terminal. 
NP_BIND   54    61  8     ATP (By similarity). 
MOTIF   140   143  4     DEXH box. 
Sequence information
Length: 634 AA [This is the length of the unprocessed precursor] Molecular weight: 72103 Da [This is the MW of the unprocessed precursor] CRC64: B786EFBA17E12F56 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MNLHAAYIDY ALRRSQHMQA EMSGADNVLL KDYQLFVAKV FLGLDSMNSL LLFQETGVGK 

        70         80         90        100        110        120 
TVTAVYMLKH LRFLYTSWTV LVLVKKALVE EPWMNTILRF APEVAKDCVF MNYDDQNFHN 

       130        140        150        160        170        180 
KFFTNIKTVS ARSRIFVIID ECHNFISKSL SREDGRARNT KHVYNFLARH IASSHNKLLC 

       190        200        210        220        230        240 
LSATPIVNNV REFALLVNLL RPGVLPPQSL FHNKRLLDEA ELVSKLGCIC SYLVHHEASI 

       250        260        270        280        290        300 
FEDVEGSELF ARKRVLLKYV RMSAKQEDIY HKARAAEFRS GIAVFRVHRR MAATFAFDEF 

       310        320        330        340        350        360 
PVRKNLTPDE YDALVASLVR DFEALFAGRA LSDATRARLR AGEPIECAAS AEDLSLYQAL 

       370        380        390        400        410        420 
YEHSCKYAEV CVAILASPGK CLVFEPFINL SGIRIFVKYL EVFGISYIEF SSRTKDTRTR 

       430        440        450        460        470        480 
AVAEFNRVEN TNGELIKTCV FSLSGNEGIS FLSINDIFIL DMTWNEASLK QIIGRAIRLH 

       490        500        510        520        530        540 
SHANNPPERR YVNVHFVVAQ LGSGAPSVDD DLLEIIQNKA REFSQLYRVL KLASIEWIHQ 

       550        560        570        580        590        600 
HCREFAPVDD EAGFRALCSR AIDVTRGAST RRALATGENI WYAFSTLMIT VHPGFKTEDG 

       610        620        630 
RVYDADGNFL TTMPERPIVR VQGTRLVYIF PELR 

Q98267 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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