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UniProtKB/Swiss-Prot entry Q98218

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NTP2_MCV1
Primary accession number Q98218
Secondary accession numbers None
Integrated into Swiss-Prot on January 11, 2001
Sequence was last modified on February 1, 1997 (Sequence version 1)
Annotations were last modified on    September 23, 2008 (Entry version 50)
Name and origin of the protein
Protein name Nucleoside triphosphatase II
Synonyms NTPase II
EC 3.6.1.15
Nucleoside triphosphate phosphohydrolase II
NPH II
Gene name
Name: NPH2
ORFNames: 50R
From
Molluscum contagiosum virus subtype 1 (MOCV) (MCVI) [TaxID: 10280] 
Taxonomy Viruses; dsDNA viruses, no RNA stage; Poxviridae; Chordopoxvirinae; Molluscipoxvirus.
Virus host Homo sapiens (Human) [TaxID: 9606]
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=8670425 [NCBI, ExPASy, EBI, Israel, Japan]
Senkevich T.G., Bugert J.J., Sisler J.R., Koonin E.V., Darai G., Moss B.;
"Genome sequence of a human tumorigenic poxvirus: prediction of specific host response-evasion genes.";
Science 273:813-816(1996).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U60315; AAC55178.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T30652; T30652.
RefSeq NP_044001.1; -.
3D structure databases
ModBase Q98218.
Family and domain databases
InterPro IPR014001; DEAD-like_N.
IPR001650; DNA/RNA_helicase_C.
IPR002464; DNA/RNA_helicase_DEAH_CS.
IPR014021; Helicase_SF1/SF2_ATP-bd.
Graphical view of domain structure.
Pfam PF00271; Helicase_C; 1.
Pfam graphical view of domain structure.
SMART SM00487; DEXDc; 1.
SM00490; HELICc; 1.
SMART graphical view of domain structure.
PROSITE PS00690; DEAH_ATP_HELICASE; 1.
PS51192; HELICASE_ATP_BIND_1; 1.
PS51194; HELICASE_CTER; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q98218.
Genome annotation databases
GeneID 1670235; -.
Other
ProtoNet Q98218.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Helicase; Hydrolase; Nucleotide-binding; Transcription.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   684  684     Nucleoside triphosphatase II. PRO_0000055188
DOMAIN   184   359  176     Helicase ATP-binding. 
DOMAIN   392   563  172     Helicase C-terminal. 
NP_BIND   197   204  8     ATP (By similarity). 
MOTIF   308   311  4     DEXH box. 
Sequence information
Length: 684 AA [This is the length of the unprocessed precursor] Molecular weight: 76557 Da [This is the MW of the unprocessed precursor] CRC64: 51072B193CCC7284 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MKNLPGVFAF PDNETIFAHA YSQRELEAML PARAGAQPHA FAYAAWPLSK HRWRGAFVCR 

        70         80         90        100        110        120 
QRGVLKLNLE LDAGAFERVP RSEAERFEPE QSDARALMHR GADGTVMSFE CYSFLRCRPG 

       130        140        150        160        170        180 
LELREAGLAL LRGLVVGGNR MRIFSGVRRA GASAATSAGM LGNESPFERA PFASLRIDAQ 

       190        200        210        220        230        240 
AALFRAWAAR RPTVVTGGTG VGKTSQVPKL LLWFNYLFGG TEDLDVLAPA RERPVVLSLP 

       250        260        270        280        290        300 
RVALVRMNGH ALRRALGFDA LEGSPVELRY GDLAPADANS SRSPFRLVVS TNQLTLGALF 

       310        320        330        340        350        360 
AHGTVILDEV HEHDQMADIM LAVLRVHRAR VDSIVLMSAT LEDDRERLQE FFPDAEFVHI 

       370        380        390        400        410        420 
PGSTRFEIRG VYVRNSSDPR DARAYDEEER RNVSAALSAH RPRAGRCGIL FVASVAQCED 

       430        440        450        460        470        480 
YARLLTREHP ELGVYVVHGK TPNVDALLAE VYASARPCVL VSTPYLESSV TIRTVTHVYD 

       490        500        510        520        530        540 
TGRVFVPAPF GGRQMLISPA MRTQRRGRVG RVMPGTYVYF YDPARLAPIK RIDSEFLYNY 

       550        560        570        580        590        600 
IIYARHYGLV LPDDLYVQPS DLELLRRCEE YLDGFGLAPE RLFELASTRY LRMVEYAKIY 

       610        620        630        640        650        660 
ARGGARAEEL NRFERDGVVT EDVLASIRAL NLRARVLSAR ARRGQFLHTC EVAFGPYAGT 

       670        680 
RFLLANRRRL RGDIFMVTER SFVL
Q98218 in FASTA format

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