ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q979A1

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name DNLI_THEVO
Primary accession number Q979A1
Secondary accession numbers None
Integrated into Swiss-Prot on May 27, 2002
Sequence was last modified on October 1, 2001 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 42)
Name and origin of the protein
Protein name DNA ligase
Synonyms EC 6.5.1.1
Polydeoxyribonucleotide synthase [ATP]
Gene name
Name: lig
OrderedLocusNames: TV1261
ORFNames: TVG1298537
From
Thermoplasma volcanium [TaxID: 50339] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Thermoplasmata; Thermoplasmatales; Thermoplasmataceae; Thermoplasma.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 51530 / DSM 4299 / IFO 15438 / JCM 9571 / GSS1;
DOI=10.1073/pnas.97.26.14257; PubMed=11121031 [NCBI, ExPASy, EBI, Israel, Japan]
Kawashima T., Amano N., Koike H., Makino S., Higuchi S., Kawashima-Ohya Y., Watanabe K., Yamazaki M., Kanehori K., Kawamoto T., Nunoshiba T., Yamamoto Y., Aramaki H., Makino K., Suzuki M.;
"Archaeal adaptation to higher temperatures revealed by genomic sequence of Thermoplasma volcanium.";
Proc. Natl. Acad. Sci. U.S.A. 97:14257-14262(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000011; BAB60403.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_111756.1; -.
3D structure databases
ModBase Q979A1.
Ontologies
GO
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0003910; Molecular function: DNA ligase (ATP) activity (inferred from electronic annotation from HAMAP).
GO:0006310; Biological process: DNA recombination (inferred from electronic annotation from HAMAP).
GO:0006281; Biological process: DNA repair (inferred from electronic annotation from HAMAP).
GO:0006260; Biological process: DNA replication (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00407; -; 1.
PBIL [Tree]
InterPro IPR000977; DNA_ligase.
IPR012309; DNA_ligase_A_C.
IPR012310; DNA_ligase_A_M.
IPR012308; DNA_ligase_A_N.
IPR016059; DNA_ligase_CS.
IPR012340; NA-bd_OB-fold.
Graphical view of domain structure.
Gene3D G3DSA:2.40.50.140; OB_NA_bd_sub; 1.
Pfam PF04679; DNA_ligase_A_C; 1.
PF01068; DNA_ligase_A_M; 1.
PF04675; DNA_ligase_A_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00574; dnl1; 1.
PROSITE PS00697; DNA_LIGASE_A1; FALSE_NEG.
PS00333; DNA_LIGASE_A2; 1.
PS50160; DNA_LIGASE_A3; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q979A1.
Genome annotation databases
GeneID 1441377; -.
GenomeReviews BA000011_GR; TV1261.
KEGG tvo:TVN1237; -.
NMPDR fig|273116.1.peg.1237; -.
Phylogenomic databases
HOGENOM Q979A1; -.
Genome annotation databases
CMR Q979A1; TV1261.
Other
ProtoNet Q979A1.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Cell cycle; Cell division; Complete proteome; DNA damage; DNA recombination; DNA repair; DNA replication; Ligase; Nucleotide-binding.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   588  588     DNA ligase. PRO_0000059622
ACT_SITE   250   250        N6-AMP-lysine intermediate (By similarity). 
Sequence information
Length: 588 AA [This is the length of the unprocessed precursor] Molecular weight: 66218 Da [This is the MW of the unprocessed precursor] CRC64: 7FC5FC2549F3CD3D [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MKFSLVTDAF EKMSKTTKRT ELTEILVELL KSADEDLQSL VYLIEGKLAP DYQGIETQMS 

        70         80         90        100        110        120 
DKLIIKALSI VSNIPEEAVS ETYSKLGDIG SVAREIAAKK NMRSLVNEDL TVKYVHDTLM 

       130        140        150        160        170        180 
RMAKTSGSGS TKARIDAYVD LALSGTPADL MYITRIITGK LRIGVSDATI LDAIILAFSD 

       190        200        210        220        230        240 
EKYSEEIENA YNFHPDLGYI AVQLRLGNLE SVINMGPTPM VPFKVMLAER LRSVDEIVQK 

       250        260        270        280        290        300 
MNGKCAFEYK YDGMRTEIHI VDEKVRLFSR GNEETTGQFP DIVKSAKETF HVSSVILDGE 

       310        320        330        340        350        360 
AVPYNPETGE LYPFQVISQR RGRKYDLDKV SNEIPITVFL FDIVYINGKD LSKTPYAERR 

       370        380        390        400        410        420 
RILEGLFKEN DNFKLAKRIV SSDTGTITKF FNQAIEDGCE GLVAKSMADD SYYKAGARGW 

       430        440        450        460        470        480 
LWIKLKRDYQ AQLWDTIDLT VVGAFMGHGR RSGTYGALLL ATYNEKNDTF ETVCKLGSGF 

       490        500        510        520        530        540 
TDDVLFSLPK RFAEFVSKEK PARVVSTIEP DVWIYPSIVM EIIGAEITIS PVHTCAFGII 

       550        560        570        580 
EKDAGLSIRF PRFTGKWRDD KKPEDSTTTQ EIIEMYKEQK KTLTEEKS
Q979A1 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by ch flag SIB Switzerland Mirror sites: Australia Brazil Canada China Korea
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!