[1]
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NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
TISSUE=Fetal kidney;
DOI=10.1006/bbrc.2000.4027; PubMed=11162435 [NCBI, ExPASy, EBI, Israel, Japan]
Lin J.-H.,
Deng G.,
Huang Q.,
Morser J.;
"KIAP, a novel member of the inhibitor of apoptosis protein family.";
Biochem. Biophys. Res. Commun. 279:820-831(2000).
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[2]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND ALTERNATIVE SPLICING (ISOFORMS 1 AND 2).
TISSUE=Melanoma;
DOI=10.1016/S0014-5793(01)02366-3; PubMed=11322947 [NCBI, ExPASy, EBI, Israel, Japan]
Ashhab Y.,
Alian A.,
Polliack A.,
Panet A.,
Yehuda D.B.;
"Two splicing variants of a new inhibitor of apoptosis gene with different biological properties and tissue distribution pattern.";
FEBS Lett. 495:56-60(2001).
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[3]
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NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
TISSUE=Kidney;
DOI=10.1074/jbc.M003670200; PubMed=11024045 [NCBI, ExPASy, EBI, Israel, Japan]
Kasof G.M.,
Gomes B.C.;
"Livin, a novel inhibitor of apoptosis protein family member.";
J. Biol. Chem. 276:3238-3246(2001).
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[4]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
DOI=10.1101/gr.1293003; PubMed=12975309 [NCBI, ExPASy, EBI, Israel, Japan]
Clark H.F.,
Gurney A.L.,
Abaya E.,
Baker K.,
Baldwin D.T.,
Brush J.,
Chen J.,
Chow B.,
Chui C.,
Crowley C.,
Currell B.,
Deuel B.,
Dowd P.,
Eaton D.,
Foster J.S.,
Grimaldi C.,
Gu Q.,
Hass P.E.,
Heldens S., ![]()
Huang A.,
Kim H.S.,
Klimowski L.,
Jin Y.,
Johnson S.,
Lee J.,
Lewis L.,
Liao D.,
Mark M.R.,
Robbie E.,
Sanchez C.,
Schoenfeld J.,
Seshagiri S.,
Simmons L.,
Singh J.,
Smith V.,
Stinson J.,
Vagts A.,
Vandlen R.L.,
Watanabe C.,
Wieand D.,
Woods K.,
Xie M.-H.,
Yansura D.G.,
Yi S.,
Yu G.,
Yuan J.,
Zhang M.,
Zhang Z.,
Goddard A.D.,
Wood W.I.,
Godowski P.J.,
Gray A.M.;
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.";
Genome Res. 13:2265-2270(2003).
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[5]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/414865a; PubMed=11780052 [NCBI, ExPASy, EBI, Israel, Japan]
Deloukas P.,
Matthews L.H.,
Ashurst J.L.,
Burton J.,
Gilbert J.G.R.,
Jones M.,
Stavrides G.,
Almeida J.P.,
Babbage A.K.,
Bagguley C.L.,
Bailey J.,
Barlow K.F.,
Bates K.N.,
Beard L.M.,
Beare D.M.,
Beasley O.P.,
Bird C.P.,
Blakey S.E.,
Bridgeman A.M., ![]()
Brown A.J.,
Buck D.,
Burrill W.D.,
Butler A.P.,
Carder C.,
Carter N.P.,
Chapman J.C.,
Clamp M.,
Clark G.,
Clark L.N.,
Clark S.Y.,
Clee C.M.,
Clegg S.,
Cobley V.E.,
Collier R.E.,
Connor R.E.,
Corby N.R.,
Coulson A.,
Coville G.J.,
Deadman R.,
Dhami P.D.,
Dunn M.,
Ellington A.G.,
Frankland J.A.,
Fraser A.,
French L.,
Garner P.,
Grafham D.V.,
Griffiths C.,
Griffiths M.N.D.,
Gwilliam R.,
Hall R.E.,
Hammond S.,
Harley J.L.,
Heath P.D.,
Ho S.,
Holden J.L.,
Howden P.J.,
Huckle E.,
Hunt A.R.,
Hunt S.E.,
Jekosch K.,
Johnson C.M.,
Johnson D.,
Kay M.P.,
Kimberley A.M.,
King A.,
Knights A.,
Laird G.K.,
Lawlor S.,
Lehvaeslaiho M.H.,
Leversha M.A.,
Lloyd C.,
Lloyd D.M.,
Lovell J.D.,
Marsh V.L.,
Martin S.L.,
McConnachie L.J.,
McLay K.,
McMurray A.A.,
Milne S.A.,
Mistry D.,
Moore M.J.F.,
Mullikin J.C.,
Nickerson T.,
Oliver K.,
Parker A.,
Patel R.,
Pearce T.A.V.,
Peck A.I.,
Phillimore B.J.C.T.,
Prathalingam S.R.,
Plumb R.W.,
Ramsay H.,
Rice C.M.,
Ross M.T.,
Scott C.E.,
Sehra H.K.,
Shownkeen R.,
Sims S.,
Skuce C.D.,
Smith M.L.,
Soderlund C.,
Steward C.A.,
Sulston J.E.,
Swann R.M.,
Sycamore N.,
Taylor R.,
Tee L.,
Thomas D.W.,
Thorpe A.,
Tracey A.,
Tromans A.C.,
Vaudin M.,
Wall M.,
Wallis J.M.,
Whitehead S.L.,
Whittaker P.,
Willey D.L.,
Williams L.,
Williams S.A.,
Wilming L.,
Wray P.W.,
Hubbard T.,
Durbin R.M.,
Bentley D.R.,
Beck S.,
Rogers J.;
"The DNA sequence and comparative analysis of human chromosome 20.";
Nature 414:865-871(2001).
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[6]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), AND VARIANT GLN-223.
TISSUE=Skin;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[7]
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FUNCTION, AND MUTAGENESIS OF 87-GLU--GLU-88; ASP-120; CYS-124 AND ASP-138.
DOI=10.1016/S0960-9822(00)00781-8; PubMed=11084335 [NCBI, ExPASy, EBI, Israel, Japan]
Vucic D.,
Stennicke H.R.,
Pisabarro M.T.,
Salvesen G.S.,
Dixit V.M.;
"ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas.";
Curr. Biol. 10:1359-1366(2000).
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[8]
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INTERACTION WITH SMAC.
DOI=10.1074/jbc.M112045200; PubMed=11801603 [NCBI, ExPASy, EBI, Israel, Japan]
Vucic D.,
Deshayes K.,
Ackerly H.,
Pisabarro M.T.,
Kadkhodayan S.,
Fairbrother W.J.,
Dixit V.M.;
"SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP).";
J. Biol. Chem. 277:12275-12279(2002).
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[9]
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ACTIVATION OF MAP KINASES.
DOI=10.1128/MCB.22.6.1754-1766.2002; PubMed=11865055 [NCBI, ExPASy, EBI, Israel, Japan]
Sanna M.G.,
da Silva Correia J.,
Ducrey O.,
Lee J.,
Nomoto K.,
Schrantz N.,
Deveraux Q.L.,
Ulevitch R.J.;
"IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition.";
Mol. Cell. Biol. 22:1754-1766(2002).
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[10]
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X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 63-179 IN COMPLEX WITH PHAGE-AND SMAC-DERIVED PEPTIDES, AND ZINC-BINDING SITES.
DOI=10.1021/bi034227t; PubMed=12846571 [NCBI, ExPASy, EBI, Israel, Japan]
Franklin M.C.,
Kadkhodayan S.,
Ackerly H.,
Alexandru D.,
Distefano M.D.,
Elliott L.O.,
Flygare J.A.,
Mausisa G.,
Okawa D.C.,
Ong D.,
Vucic D.,
Deshayes K.,
Fairbrother W.J.;
"Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ML-IAP).";
Biochemistry 42:8223-8231(2003).
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[11]
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X-RAY CRYSTALLOGRAPHY (1.71 ANGSTROMS) OF 63-159, AND ZINC-BINDING SITES.
DOI=10.1042/BJ20041108; PubMed=15485396 [NCBI, ExPASy, EBI, Israel, Japan]
Vucic D.,
Franklin M.C.,
Wallweber H.J.,
Das K.,
Eckelman B.P.,
Shin H.,
Elliott L.O.,
Kadkhodayan S.,
Deshayes K.,
Salvesen G.S.,
Fairbrother W.J.;
"Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP.";
Biochem. J. 385:11-20(2005).
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