ID   DHSB_SALTY              Reviewed;         238 AA.
AC   Q8ZQU2;
DT   06-JUN-2002, integrated into UniProtKB/Swiss-Prot.
DT   06-JUN-2002, sequence version 2.
DT   25-NOV-2008, entry version 49.
DE   RecName: Full=Succinate dehydrogenase iron-sulfur subunit;
DE            EC=1.3.99.1;
GN   Name=sdhB; OrderedLocusNames=STM0735;
OS   Salmonella typhimurium.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=602;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   MEDLINE=21534948; PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M.,
RA   Waterston R., Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium
RT   LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Two distinct, membrane-bound, FAD-containing enzymes are
CC       responsible for the catalysis of fumarate and succinate
CC       interconversion; the fumarate reductase is used in anaerobic
CC       growth, and the succinate dehydrogenase is used in aerobic growth
CC       (By similarity).
CC   -!- CATALYTIC ACTIVITY: Succinate + acceptor = fumarate + reduced
CC       acceptor.
CC   -!- COFACTOR: Binds 1 2Fe-2S cluster.
CC   -!- COFACTOR: Binds 1 3Fe-4S cluster.
CC   -!- COFACTOR: Binds 1 4Fe-4S cluster.
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle.
CC   -!- SUBUNIT: Part of an enzyme complex containing four subunits: a
CC       flavoprotein, an iron-sulfur, cytochrome b-556, and an hydrophobic
CC       anchor protein (By similarity).
CC   -!- SIMILARITY: Belongs to the succinate dehydrogenase/fumarate
CC       reductase iron-sulfur protein family.
CC   -!- SIMILARITY: Contains 1 2Fe-2S ferredoxin-type domain.
CC   -!- SIMILARITY: Contains 1 4Fe-4S ferredoxin-type domain.
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DR   EMBL; AE008730; AAL19679.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_459720.1; -.
DR   HSSP; P07014; 1NEK.
DR   SMR; Q8ZQU2; 1-238.
DR   GeneID; 1252255; -.
DR   GenomeReviews; AE006468_GR; STM0735.
DR   KEGG; stm:STM0735; -.
DR   StyGene; SG?????; sdhB.
DR   HOGENOM; Q8ZQU2; -.
DR   BioCyc; STYP99287:STM0735-MON; -.
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0051538; F:3 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000104; F:succinate dehydrogenase activity; IEA:EC.
DR   GO; GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   InterPro; IPR006058; 2Fe2S_fd_BS.
DR   InterPro; IPR001450; 4Fe4S_Fe_S_bd.
DR   InterPro; IPR012675; b-grasp_ferredoxin-like.
DR   InterPro; IPR001041; Ferredoxin.
DR   InterPro; IPR012285; Fum_reductase_C.
DR   InterPro; IPR004489; Succ_DHase/fum_Rdtase_Fe-S.
DR   Gene3D; G3DSA:3.10.20.30; Ferredoxin_fold; 1.
DR   Gene3D; G3DSA:1.10.1060.10; Fum_reductase_C; 1.
DR   TIGRFAMs; TIGR00384; dhsB; 1.
DR   PROSITE; PS00197; 2FE2S_FER_1; FALSE_NEG.
DR   PROSITE; PS51085; 2FE2S_FER_2; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
PE   3: Inferred from homology;
KW   2Fe-2S; 3Fe-4S; 4Fe-4S; Complete proteome; Electron transport; Iron;
KW   Iron-sulfur; Metal-binding; Oxidoreductase; Transport;
KW   Tricarboxylic acid cycle.
FT   CHAIN         1    238       Succinate dehydrogenase iron-sulfur
FT                                subunit.
FT                                /FTId=PRO_0000158692.
FT   DOMAIN        1     97       2Fe-2S ferredoxin-type.
FT   DOMAIN      139    169       4Fe-4S ferredoxin-type.
FT   METAL        55     55       Iron-sulfur 1 (2Fe-2S) (By similarity).
FT   METAL        60     60       Iron-sulfur 1 (2Fe-2S) (By similarity).
FT   METAL        63     63       Iron-sulfur 1 (2Fe-2S) (Potential).
FT   METAL        75     75       Iron-sulfur 1 (2Fe-2S) (By similarity).
FT   METAL       149    149       Iron-sulfur 2 (4Fe-4S) (By similarity).
FT   METAL       152    152       Iron-sulfur 2 (4Fe-4S) (By similarity).
FT   METAL       155    155       Iron-sulfur 2 (4Fe-4S) (By similarity).
FT   METAL       159    159       Iron-sulfur 3 (3Fe-4S) (By similarity).
FT   METAL       206    206       Iron-sulfur 3 (3Fe-4S) (By similarity).
FT   METAL       212    212       Iron-sulfur 3 (3Fe-4S) (By similarity).
FT   METAL       216    216       Iron-sulfur 2 (4Fe-4S) (By similarity).
SQ   SEQUENCE   238 AA;  26733 MW;  7628F9F9F95611F3 CRC64;
     MKLEFSIYRY NPDVDNAPRM QDYTLEGEEG RDMMLLDALI QLKEKDPSLS FRRSCREGVC
     GSDGLNMNGK NGLACITPIS ALTQPGKKIV IRPLPGLPVI RDLVVDMGQF YAQYEKIKPY
     LLNNGQNPPA REHLQMPEQR EKLDGLYECI LCACCSTSCP SFWWNPDKFI GPAGLLAAYR
     FLIDSRDTET DSRLEGMSDA FSVFRCHSIM NCVSVCPKGL NPTRAIGHIK SMLLQRSA
//