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UniProtKB/Swiss-Prot entry Q8ZPV0

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ASTD_SALTY
Primary accession number Q8ZPV0
Secondary accession numbers None
Integrated into Swiss-Prot on November 28, 2006
Sequence was last modified on March 1, 2002 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 39)
Name and origin of the protein
Protein name N-succinylglutamate 5-semialdehyde dehydrogenase
Synonyms EC 1.2.1.71
Succinylglutamic semialdehyde dehydrogenase
SGSD
Gene name
Name: astD
OrderedLocusNames: STM1305
From
Salmonella typhimurium [TaxID: 602] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Salmonella.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=LT2 / SGSC1412 / ATCC 700720;
DOI=10.1038/35101614; PubMed=11677609 [NCBI, ExPASy, EBI, Israel, Japan]
McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P., Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D., Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E., Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R., Wilson R.K.;
"Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
Nature 413:852-856(2001).
[2]
 INDUCTION.
PubMed=10074092 [NCBI, ExPASy, EBI, Israel, Japan]
Lu C.-D., Abdelal A.T.;
"Role of ArgR in activation of the ast operon, encoding enzymes of the arginine succinyltransferase pathway in Salmonella typhimurium.";
J. Bacteriol. 181:1934-1938(1999).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE008756; AAL20230.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_460271.1; -.
3D structure databases
ModBase Q8ZPV0.
Enzyme and pathway databases
BioCyc STYP99287:STM1305-MON; -.
Organism-specific databases
StyGene SG?????; astD.
Ontologies
GO
GO:0043824; Molecular function: succinylglutamate-semialdehyde dehydrogenase activity (inferred from electronic annotation from InterPro).
GO:0019544; Biological process: arginine catabolic process to glutamate (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_01174; -; 1.
PBIL [Tree]
InterPro IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
IPR017649; SuccinylGlu_semiald_DH_AstD.
Graphical view of domain structure.
Gene3D G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11699; Aldehyde_dehyd; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.
ProtoNet Q8ZPV0.
Genome annotation databases
GeneID 1252823; -.
GenomeReviews AE006468_GR; STM1305.
KEGG stm:STM1305; -.
NMPDR fig|99287.1.peg.1263; -.
Phylogenomic databases
HOGENOM Q8ZPV0; -.
Genome annotation databases
CMR Q8ZPV0; STM1305.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Arginine metabolism; Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   492  492     N-succinylglutamate 5-semialdehyde dehydrogenase. PRO_0000262422
NP_BIND   220   225  6     NAD (By similarity). 
ACT_SITE   243   243        By similarity. 
ACT_SITE   277   277        By similarity. 
Sequence information
Length: 492 AA [This is the length of the unprocessed precursor] Molecular weight: 53017 Da [This is the MW of the unprocessed precursor] CRC64: 2B9DD9F7A475D10F [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTLWINGDWI TGQGERRRKT NPVSAEILWQ GNDANAAQVA EACQAARAAF PRWARQPFAA 

        70         80         90        100        110        120 
RQAIVEKFAA LLEAHKAELT EVIARETGKP RWEAATEVTA MINKIAISIK AYHARTGAQK 

       130        140        150        160        170        180 
SELVDGAATL RHRPHGVLAV FGPYNFPGHL PNGHIVPALL AGNTLIFKPS ELTPWTGETV 

       190        200        210        220        230        240 
IKLWERAGLP AGVLNLVQGG RETGQALSSL DDLDGLLFTG SASTGYQLHR QLSGQPEKIL 

       250        260        270        280        290        300 
ALEMGGNNPL IIEDAANIDA AVHLTLQSAF ITAGQRCTCA RRLLVKQGAQ GDAFLARLVD 

       310        320        330        340        350        360 
VAGRLQPGRW DDDPQPFIGG LISAQAAQHV MEAWRQREAL GGRTLLAPRK VKEGTSLLTP 

       370        380        390        400        410        420 
GIIELTGVAD VPDEEVFGPL LNVWRYAHFD EAIRLANNTR FGLSCGLVST DRAQFEQLLL 

       430        440        450        460        470        480 
EARAGIVNWN KPLTGAASTA PFGGVGASGN HRPSAWYAAD YCAWPMASLE SPELTLPATL 

       490 
SPGLDFSRRE AV
Q8ZPV0 in FASTA format

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