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UniProtKB/Swiss-Prot entry Q8ZD80


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NADB_YERPE
Primary accession number Q8ZD80
Secondary accession number Q0WDI1
Integrated into Swiss-Prot on August 30, 2002
Sequence was last modified on August 30, 2002 (Sequence version 2)
Annotations were last modified on    November 25, 2008 (Entry version 54)
Name and origin of the protein
Protein name L-aspartate oxidase
Synonyms LASPO
EC 1.4.3.16
Quinolinate synthetase B
Gene name
Name: nadB
OrderedLocusNames: YPO2710, y1289, YP_2514
From
Yersinia pestis [TaxID: 632] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Yersinia.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CO-92 / Biovar Orientalis;
DOI=10.1038/35097083; PubMed=11586360 [NCBI, ExPASy, EBI, Israel, Japan]
Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G., Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L., Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M., Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T., Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S., Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G.;
"Genome sequence of Yersinia pestis, the causative agent of plague.";
Nature 413:523-527(2001).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=KIM5 / Biovar Mediaevalis;
DOI=10.1128/JB.184.16.4601-4611.2002; PubMed=12142430 [NCBI, ExPASy, EBI, Israel, Japan]
Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P., Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D., Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A., Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
"Genome sequence of Yersinia pestis KIM.";
J. Bacteriol. 184:4601-4611(2002).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=91001 / Biovar Mediaevalis;
DOI=10.1093/dnares/11.3.179; PubMed=15368893 [NCBI, ExPASy, EBI, Israel, Japan]
Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.;
"Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans.";
DNA Res. 11:179-197(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL590842; CAL21329.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE009952; AAM84863.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE017042; AAS62712.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR AF0330; AF0330.
RefSeq NP_668612.1; -.
NP_993835.1; -.
3D structure databases
HSSP P10902; 1CHU. [HSSP ENTRY / PDB]
SMR Q8ZD80; 6-533.
ModBase Q8ZD80.
Enzyme and pathway databases
BioCyc YPES187410:Y1289-MON; -.
YPES214092:YPO2710-MON; -.
YPES229193:YP2514-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from InterPro).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0008734; Molecular function: L-aspartate oxidase activity (inferred from electronic annotation from InterPro).
GO:0009435; Biological process: NAD biosynthetic process (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR003953; FAD_bind2_N.
IPR013027; FAD_pyr_nucl-diS_OxRdtase.
IPR004112; Fum_Rdtase/Succ_DHase_flav_C.
IPR005288; NadB.
IPR001100; Pyr_nuc-diS_OxRdtase.
Graphical view of domain structure.
Pfam PF00890; FAD_binding_2; 1.
PF02910; Succ_DH_flav_C; 1.
Pfam graphical view of domain structure.
PRINTS PR00368; FADPNR.
PR00411; PNDRDTASEI.
TIGRFAMs TIGR00551; nadB; 1.
ProtoNet Q8ZD80.
Genome annotation databases
GeneID 1146236; -.
2764388; -.
GenomeReviews AE009952_GR; y1289.
AE017042_GR; YP_2514.
AL590842_GR; YPO2710.
KEGG ype:YPO2710; -.
ypk:y1289; -.
ypm:YP_2514; -.
Phylogenomic databases
HOGENOM Q8ZD80; -.
Genome annotation databases
CMR Q8ZD80; YPO2710.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; FAD; Flavoprotein; Oxidoreductase; Pyridine nucleotide biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   533  533     L-aspartate oxidase. PRO_0000184406
NP_BIND   12    26  15     FAD (Potential). 
ACT_SITE   244   244        By similarity. 
ACT_SITE   263   263        By similarity. 
Sequence information
Length: 533 AA [This is the length of the unprocessed precursor] Molecular weight: 59294 Da [This is the MW of the unprocessed precursor] CRC64: 909E8BFEB15BD2BD [This is a checksum on the sequence]
        10         20         30         40         50         60 
MQSSSEHISD VLIIGSGAAG LSLALRLAPH CKVTVLSKGP LNEGATFYAQ GGIAAVFDET 

        70         80         90        100        110        120 
DSISSHVDDT LIAGAGLCDK EAVEFIASNA RSCVQWLIDQ GVLFDTETSA NGEERYHLTR 

       130        140        150        160        170        180 
EGGHSHRRIL HTADATGKEV ETTLVGKASN HPNISVKERC NAVDLITSNK IGLAGTKRVV 

       190        200        210        220        230        240 
GAYVWNRELE KVETFRAKAV VLATGGAAKV YQYTTNPDIS SGDGIAMAWR AGCRVANLEF 

       250        260        270        280        290        300 
NQFHPTCLFH PQARNFLLTE ALRGEGAYLK RPDGSRFMLD FDPRGELAPR DIVARAIDHE 

       310        320        330        340        350        360 
MKRLGADCMY LDISHKPTDF VMQHFPMIYE KLLSLGIDLT KEAIPIVPAA HYTCGGVMVD 

       370        380        390        400        410        420 
QHGRTDLDGL YAIGEVSYTG LHGANRMASN SLLECLVYGW SAAEDILTRL PTAKLAKHLP 

       430        440        450        460        470        480 
DWDESRVDNS DERVVIQHNW HELRLFMWDY VGIVRTTKRL ERALRRINTL QQEIDEYYAN 

       490        500        510        520        530 
FRISNNLLEL RNLVQVAELI VRCAMERKES RGLHYTLDYP DQIENPQPTI LHP 

Q8ZD80 in FASTA format

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