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[1]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1066804; PubMed=11743193 [NCBI, ExPASy, EBI, Israel, Japan]
Wood D.W.,
Setubal J.C.,
Kaul R.,
Monks D.E.,
Kitajima J.P.,
Okura V.K.,
Zhou Y.,
Chen L.,
Wood G.E.,
Almeida N.F. Jr.,
Woo L.,
Chen Y.,
Paulsen I.T.,
Eisen J.A.,
Karp P.D.,
Bovee D. Sr.,
Chapman P.,
Clendenning J.,
Deatherage G., ![]()
Gillet W.,
Grant C.,
Kutyavin T.,
Levy R.,
Li M.-J.,
McClelland E.,
Palmieri A.,
Raymond C.,
Rouse G.,
Saenphimmachak C.,
Wu Z.,
Romero P.,
Gordon D.,
Zhang S.,
Yoo H.,
Tao Y.,
Biddle P.,
Jung M.,
Krespan W.,
Perry M.,
Gordon-Kamm B.,
Liao L.,
Kim S.,
Hendrick C.,
Zhao Z.-Y.,
Dolan M.,
Chumley F.,
Tingey S.V.,
Tomb J.-F.,
Gordon M.P.,
Olson M.V.,
Nester E.W.;
"The genome of the natural genetic engineer Agrobacterium tumefaciens C58.";
Science 294:2317-2323(2001).
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[2]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1066803; PubMed=11743194 [NCBI, ExPASy, EBI, Israel, Japan]
Goodner B.,
Hinkle G.,
Gattung S.,
Miller N.,
Blanchard M.,
Qurollo B.,
Goldman B.S.,
Cao Y.,
Askenazi M.,
Halling C.,
Mullin L.,
Houmiel K.,
Gordon J.,
Vaudin M.,
Iartchouk O.,
Epp A.,
Liu F.,
Wollam C.,
Allinger M., ![]()
Doughty D.,
Scott C.,
Lappas C.,
Markelz B.,
Flanagan C.,
Crowell C.,
Gurson J.,
Lomo C.,
Sear C.,
Strub G.,
Cielo C.,
Slater S.;
"Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58.";
Science 294:2323-2328(2001).
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- FUNCTION: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity).
- CATALYTIC ACTIVITY: Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. Alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec; and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs).
- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
- SIMILARITY: Belongs to the peptidase S14 family [view classification].
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 210 AA [This is the length of the unprocessed precursor] |
Molecular weight: 23301 Da [This is the MW of the unprocessed precursor] |
CRC64: 30396021EC5CA182 [This is a checksum on the sequence] |
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10 20 30 40 50 60
MKNPVDTAMA LVPMVVEQTN RGERSYDIFS RLLKERIIFL TGPVEDQMAS LVCAQLLFLE
70 80 90 100 110 120
AENPKKEIAL YINSPGGVVT AGMAIYDTMQ FIRPAVSTLC VGQAASMGSL LLAAGEKGMR
130 140 150 160 170 180
FATPNARIMV HQPSGGFQGQ ASDIERHARD IIKMKRRLNE VYVKHTGRTL EEVEKTLDRD
190 200 210
HFMDADEAKD WGVIDKILTS RQEMEGAVAN
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Q8UFY6 in FASTA format |
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