ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q8UFK2


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name LEXA_AGRT5
Primary accession number Q8UFK2
Secondary accession numbers None
Integrated into Swiss-Prot on November 25, 2002
Sequence was last modified on June 1, 2002 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 47)
Name and origin of the protein
Protein name LexA repressor
Synonym EC 3.4.21.88
Gene name
Name: lexA
OrderedLocusNames: Atu1395
ORFNames: AGR_C_2577
From
Agrobacterium tumefaciens (strain C58 / ATCC 33970) [TaxID: 176299] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1066804; PubMed=11743193 [NCBI, ExPASy, EBI, Israel, Japan]
Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K., Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y., Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P., Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R., Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G., Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y., Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S., Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F., Gordon M.P., Olson M.V., Nester E.W.;
"The genome of the natural genetic engineer Agrobacterium tumefaciens C58.";
Science 294:2317-2323(2001).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1066803; PubMed=11743194 [NCBI, ExPASy, EBI, Israel, Japan]
Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B., Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K., Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M., Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C., Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
"Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58.";
Science 294:2323-2328(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE007869; AAK87187.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR AC2748; AC2748.
B97529; B97529.
RefSeq NP_354402.1; -.
3D structure databases
HSSP P03033; 1JHC. [HSSP ENTRY / PDB]
ModBase Q8UFK2.
Protein family/group databases
MEROPS S24.001; -.
Ontologies
GO
GO:0003677; Molecular function: DNA binding (inferred from electronic annotation from HAMAP).
GO:0004252; Molecular function: serine-type endopeptidase activity (inferred from electronic annotation from HAMAP).
GO:0006281; Biological process: DNA repair (inferred from electronic annotation from HAMAP).
GO:0006260; Biological process: DNA replication (inferred from electronic annotation from HAMAP).
GO:0045892; Biological process: negative regulation of transcription, DNA-dependent (inferred from electronic annotation from HAMAP).
GO:0006508; Biological process: proteolysis (inferred from electronic annotation from InterPro).
GO:0009432; Biological process: SOS response (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00015; -; 1.
PBIL [Tree]
InterPro IPR006199; LexA_DNA_bd.
IPR006200; Pept_S24_LexA.
IPR006197; Pept_S24_SOS.
IPR011056; Peptidase_S24_S26_C.
IPR011991; Wing_hlx_DNA_bd.
Graphical view of domain structure.
Gene3D G3DSA:2.10.109.10; Pept_S24_S26_C; 1.
G3DSA:1.10.10.10; Wing_hlx_DNA_bd; 1.
Pfam PF01726; LexA_DNA_bind; 1.
PF00717; Peptidase_S24; 1.
Pfam graphical view of domain structure.
PRINTS PR00726; LEXASERPTASE.
TIGRFAMs TIGR00498; lexA; 1.
ProtoNet Q8UFK2.
Genome annotation databases
GeneID 1133433; -.
GenomeReviews AE007869_GR; Atu1395.
KEGG atc:AGR_C_2577; -.
atu:Atu1395; -.
Phylogenomic databases
HOGENOM Q8UFK2; -.
Genome annotation databases
CMR Q8UFK2; Atu1395.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Autocatalytic cleavage; Complete proteome; DNA damage; DNA repair; DNA replication; DNA-binding; Hydrolase; Repressor; SOS response; Transcription; Transcription regulation.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   240  240     LexA repressor. PRO_0000169998
DNA_BIND   26    46  21     H-T-H motif (By similarity). 
ACT_SITE   160   160        For autocatalytic cleavage activity (By similarity). 
ACT_SITE   198   198        For autocatalytic cleavage activity (By similarity). 
SITE   125   126  2     Cleavage; by autolysis (By similarity). 
Sequence information
Length: 240 AA [This is the length of the unprocessed precursor] Molecular weight: 26033 Da [This is the MW of the unprocessed precursor] CRC64: 2FA935A5EBA20180 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MLTRKQQELL LFIHERMKES GVPPSFDEMK DALDLASKSG IHRLITALEE RGFIRRLPNR 

        70         80         90        100        110        120 
ARALEVIKLP EAYTPGARPQ RGFSPSVIEG SLGKPKEPEP APAVKAPAND FAGAATIPVM 

       130        140        150        160        170        180 
GRIAAGVPIS AIQNNTHDLA VPVDMLGSGE HYALEVKGDS MIEAGIFDGD TVIIRNGNTA 

       190        200        210        220        230        240 
NPGDIVVALV DDEEATLKRF RRKGASIALE AANPAYETRI FGPDRVKIQG KLVGLIRRYH 

Q8UFK2 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by ch flag SIB Switzerland Mirror sites: Australia  Brazil  Canada  China  Korea
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!