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UniProtKB/Swiss-Prot entry Q8UD54


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name QUEF_AGRT5
Primary accession number Q8UD54
Secondary accession number Q7CXG8
Integrated into Swiss-Prot on November 22, 2005
Sequence was last modified on November 22, 2005 (Sequence version 2)
Annotations were last modified on    November 25, 2008 (Entry version 41)
Name and origin of the protein
Protein name NADPH-dependent 7-cyano-7-deazaguanine reductase
Synonyms EC 1.7.1.13
7-cyano-7-carbaguanine reductase
PreQ(0) reductase
NADPH-dependent nitrile oxidoreductase
Gene name
Name: queF
OrderedLocusNames: Atu2273
ORFNames: AGR_C_4128
From
Agrobacterium tumefaciens (strain C58 / ATCC 33970) [TaxID: 176299] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1066804; PubMed=11743193 [NCBI, ExPASy, EBI, Israel, Japan]
Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K., Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y., Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P., Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R., Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G., Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y., Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S., Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F., Gordon M.P., Olson M.V., Nester E.W.;
"The genome of the natural genetic engineer Agrobacterium tumefaciens C58.";
Science 294:2317-2323(2001).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1066803; PubMed=11743194 [NCBI, ExPASy, EBI, Israel, Japan]
Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B., Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K., Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M., Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C., Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
"Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58.";
Science 294:2323-2328(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE007869; AAK88014.2; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR AH2855; AH2855.
E97632; E97632.
RefSeq NP_355229.2; -.
3D structure databases
ModBase Q8UD54.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0003934; Molecular function: GTP cyclohydrolase I activity (inferred from electronic annotation from InterPro).
GO:0046857; Molecular function: oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor (inferred from electronic annotation from HAMAP).
GO:0033739; Molecular function: queuine synthase activity (inferred from electronic annotation from EC).
GO:0019438; Biological process: aromatic compound biosynthetic process (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0008616; Biological process: queuosine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00818; -; 1.
PBIL [Tree]
InterPro IPR016856; CN_OxRdtase_NADPH-dep_QueF.
IPR001474; GTP_CycOHase_I.
Graphical view of domain structure.
Pfam PF01227; GTP_cyclohydroI; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF027377; Nitrile_oxidored_QueF; 1.
TIGRFAMs TIGR03139; QueF-II; 1.
ProtoNet Q8UD54.
Genome annotation databases
GeneID 1134311; -.
GenomeReviews AE007869_GR; Atu2273.
KEGG atc:AGR_C_4128; -.
atu:Atu2273; -.
Phylogenomic databases
HOGENOM Q8UD54; -.
Genome annotation databases
CMR Q8UD54; Atu2273.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; NADP; Oxidoreductase; Queuosine biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   154  154     NADPH-dependent 7-cyano-7-deazaguanine reductase. PRO_0000162947
Sequence information
Length: 154 AA [This is the length of the unprocessed precursor] Molecular weight: 17042 Da [This is the MW of the unprocessed precursor] CRC64: 997C97FE9A2BD86B [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSVTDVSGLS QLGTKVDTPE SPEKAVLEKV PNGNAGTDYV VRFTAPEFTS LCPMTGQPDF 

        70         80         90        100        110        120 
AHIVIDYIPG DFLVESKSLK LFLQSFRNHG AFHEDCSVYI AKRLVELLQP KWLRIGAYWY 

       130        140        150 
PRGGIPIDVF WQTGAAPEGV WLPDQGVAPY RGRG 

Q8UD54 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
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